Abstract
The use of cardiac ultrasound for right ventricular (RV) assessment has increased in critical care research, mostly notable in the critical care unit, but also in the emergency department and in anesthesia. Over the past few years, there has been an explosion of literature in the field of RV functional assessment. A multitude of disease processes has been assessed by ultrasound, particularly in patients with the otential for increased RV afterload, such as pulmonary embolism and acute respiratory distress syndrome. The RV has a complex morphology, wraps anteriorly around the left ventricle and is the first chamber of the heart in contact with the ultrasound waves. The fiber orientation in the right ventricle is largely longitudinal. Therefore, RV functional assessment includes measures of global function including tricuspid annular plane systolic excursion (TAPSE; the most common single index used to assess RV function in POCUS studies) as well as fractional area of change (FAC). RV dysfunction in critically ill infants has been associated with increased morbidity and mortality. An understanding of RV anatomy and the effect varying pathophysiologies can have on the RV morphology can allow clinicians to utilize POCUS to augment clinical acumen and potentially affect management.
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References
Bleeker GB. Assessing right ventricular function: the role of echocardiography and complementary technologies. Heart. 2006;92:i19–26.
Sengupta PP, Krishnamoorthy VK, Korinek J, Narula J, Vannan MA, Lester SJ, Tajik JA, Seward JB, Khandheria BK, Belohlavek M. Left ventricular form and function revisited: applied translational science to cardiovascular ultrasound imaging. J Am Soc Echocardiogr. 2007;20:539–51.
Piazza G, Goldhaber SZ. The acutely decompensated right ventricle. Chest. 2005;128:1836–52.
Levitov A, Frankel HL, Blaivas M, Kirkpatrick AW, Su E, Evans D, Summerfield DT, Slonim A, Breitkreutz R, Price S, McLaughlin M, Marik PE, Elbarbary M. Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients-part II: cardiac ultrasonography. Crit Care Med. 2016;44:1206–27.
Filopei J, Acquah SO, Bondarsky EE, Steiger DJ, Ramesh N, Ehrlich M, Patrawalla P. Diagnostic accuracy of point-of-care ultrasound performed by pulmonary critical care physicians for right ventricle assessment in patients with acute pulmonary embolism*. Crit Care Med. 2017;45:2040–5.
Huang SJ, Nalos M, Smith L, Rajamani A, McLean AS. The use of echocardiographic indices in defining and assessing right ventricular systolic function in critical care research. Intensive Care Med. 2018;44:868–83.
Malowitz JR, Forsha DE, Smith PB, Cotten CM, Barker PC, Tatum GH. Right ventricular echocardiographic indices predict poor outcomes in infants with persistent pulmonary hypertension of the newborn. Eur Heart J Cardiovasc Imaging. 2015;16:1224–31.
Jone P-N, Hinzman J, Wagner BD, Ivy DD, Younoszai A. Right ventricular to left ventricular diameter ratio at end-systole in evaluating outcomes in children with pulmonary hypertension. J Am Soc Echocardiogr. 2014;27:172–8.
Koestenberger M, Ravekes W, Everett AD, Stueger HP, Heinzl B, Gamillscheg A, Cvirn G, Boysen A, Fandl A, Nagel B. Right ventricular function in infants, children and adolescents: reference values of the tricuspid annular plane systolic excursion (TAPSE) in 640 healthy patients and calculation of z score values. J Am Soc Echocardiogr. 2009;22:715–9.
Breatnach CR, Levy PT, James AT, Franklin O, El-Khuffash A. Novel echocardiography methods in the functional assessment of the newborn heart. Neonatology. 2016;110:248–60.
Lee JZ, Low S-W, Pasha AK, Howe CL, Lee KS, Suryanarayana PG. Comparison of tricuspid annular plane systolic excursion with fractional area change for the evaluation of right ventricular systolic function: a meta-analysis. Open Heart. 2018;5:e000667.
Levy PT, Dioneda B, Holland MR, Sekarski TJ, Lee CK, Mathur A, Cade WT, Cahill AG, Hamvas A, Singh GK. Right ventricular function in preterm and term neonates: reference values for right ventricle areas and fractional area of change. J Am Soc Echocardiogr. 2015;28:559–69.
Mourani PM, Sontag MK, Younoszai A, Ivy DD, Abman SH. Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics. 2008;121:317–25.
Orde S, Slama M, Yastrebov K, Mclean A, Huang S. Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures. Crit Care. 2019;23:70.
Currie PJ, Seward JB, Chan K-L, Fyfe DA, Hagler DJ, Mair DD, Reeder GS, Nishimura RA, Tajik AJ. Continuous wave doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol. 1985;6:750–6.
de Boode WP, Singh Y, Molnar Z, Schubert U, Savoia M, Sehgal A, Levy PT, McNamara PJ, El-Khuffash A, European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE). Application of neonatologist performed echocardiography in the assessment and management of persistent pulmonary hypertension of the newborn. Pediatr Res. 2018;84:68–77.
Kovács A, Lakatos B, Tokodi M, Merkely B. Right ventricular mechanical pattern in health and disease: beyond longitudinal shortening. Heart Fail Rev. 2019;24:511–20.
Musewe NN, Smallhorn JF, Benson LN, Burrows PE, Freedom RM. Validation of Doppler-derived pulmonary arterial pressure in patients with ductus arteriosus under different hemodynamic states. Circulation. 1987;76:1081–91.
Burkett DA, Patel SS, Mertens L, Friedberg MK, Ivy DD. Relationship between left ventricular geometry and invasive hemodynamics in pediatric pulmonary hypertension. Circ Cardiovasc Imaging. 2020;13:e009825.
Levy PT, Patel MD, Groh G, Choudhry S, Murphy J, Holland MR, Hamvas A, Grady MR, Singh GK. Pulmonary artery acceleration time provides a reliable estimate of invasive pulmonary hemodynamics in children. J Am Soc Echocardiogr. 2016;29:1056–65.
Koestenberger M, Nagel B, Ravekes W, Urlesberger B, Raith W, Avian A, Halb V, Cvirn G, Fritsch P, Gamillscheg A. Systolic right ventricular function in preterm and term neonates: reference values of the tricuspid annular plane systolic excursion (TAPSE) in 258 patients and calculation of Z-score values. Neonatology. 2011;100:85–92.
Forfia PR, Fisher MR, Mathai SC, Housten-Harris T, Hemnes AR, Borlaug BA, Chamera E, Corretti MC, Champion HC, Abraham TP. Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med. 2006;174:1034–41.
Koestenberger M, Apitz C, Abdul-Khaliq H, Hansmann G. Transthoracic echocardiography for the evaluation of children and adolescents with suspected or confirmed pulmonary hypertension. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and D6PK. Heart. 2016;102:ii14–22.
Sehgal A, Malikiwi A, Paul E, Tan K, Menahem S. Right ventricular function in infants with bronchopulmonary dysplasia: association with respiratory sequelae. Neonatology. 2016;109:289–96.
Jone P-N, Patel SS, Cassidy C, Ivy DD. Three-dimensional echocardiography of right ventricular function correlates with severity of pediatric pulmonary hypertension. Congenit Heart Dis. 2016;11:562–9.
Jone P-N, Schäfer M, Pan Z, Bremen C, Ivy DD. 3D echocardiographic evaluation of right ventricular function and strain: a prognostic study in paediatric pulmonary hypertension. Eur Heart J Cardiovasc Imaging. 2018;19:1026–33.
Koestenberger M, Friedberg MK, Nestaas E, Michel-Behnke I, Hansmann G. Transthoracic echocardiography in the evaluation of pediatric pulmonary hypertension and ventricular dysfunction. Pulm Circ. 2016;6:15–29.
Jone P-N, Ivy DD. Comprehensive noninvasive evaluation of right ventricle-pulmonary circulation axis in pediatric patients with pulmonary hypertension. Curr Treat Options Cardiovasc Med. 2019;21:6.
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Bhombal, S., Noori, S., Singh, Y., Fraga, M.V. (2023). Focused Ultrasound in Right Ventricular Function and Pulmonary Hypertension. In: Singh, Y., Tissot, C., Fraga, M.V., Conlon, T. (eds) Point-of-Care Ultrasound for the Neonatal and Pediatric Intensivist. Springer, Cham. https://doi.org/10.1007/978-3-031-26538-9_6
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