Abstract
Non-invasive ventilation approaches are increasingly used in the neonatal intensive care unit to provide alternative methods of ventilation support. While in the delivery room most commonly cold dry air is used, in the neonatal intensive care unit, humidified and warmed air is used. This chapter will discuss the currently available evidence for using humidification during non-invasive respiratory support.
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References
Bahman-Bijari B, Malekiyan A, Niknafs P, Baneshi M-R. Bubble-CPAP vs. ventilatory-CPAP in preterm infants with respiratory distress. Iran J Pediatr. 2011;21:151–8.
Tagare A, Kadam S, Vaidya U, Pandit A, Patole S. Bubble CPAP versus ventilator CPAP in preterm neonates with early onset respiratory distress—a randomized controlled trial. J Trop Pediatr. 2013;59:113–9. https://doi.org/10.1093/tropej/fms061.
Bhatti A, Khan J, Murki S, Sundaram V, Saini SS, Kumar P. Nasal jet-CPAP (variable flow) versus bubble-CPAP in preterm infants with respiratory distress: an open label, randomized controlled trial. J Perinatol. 2015;35:935–40. https://doi.org/10.1038/jp.2015.98.
Bharadwaj SK, Alonazi A, Banfield L, Dutta S, Mukerji A. Bubble versus other continuous positive airway pressure forms: a systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed. 2020;105:318165. https://doi.org/10.1136/archdischild-2019-318165.
Chao K-Y, Chen Y-L, Tsai L-Y, Chien Y-H, Mu S-C. The role of heated humidified high-flow nasal cannula as noninvasive respiratory support in neonates. Pediatr Neonatol. 2017;58:295–302. https://doi.org/10.1016/j.pedneo.2016.08.007.
Yoder BA, Stoddard RA, Li M, King J, Dirnberger DR, Abbasi S. Heated, humidified high-flow nasal cannula versus nasal CPAP for respiratory support in neonates. Pediatrics. 2013;131:1482–90. https://doi.org/10.1542/peds.2012-2742.
Manley BJ, Owen LS, Doyle LW, Andersen CC, Cartwright DW, Pritchard MA, et al. High-flow nasal cannulae in very preterm infants after extubation. N Engl J Med. 2013;369:1425–33. https://doi.org/10.1056/nejmoa1300071.
Roberts CT, Owen L, Manley BJ, Frøisland DH, Donath S, Dalziel KM, et al. Nasal high-flow therapy for primary respiratory support in preterm infants. N Engl J Med. 2016;375:1142–51. https://doi.org/10.1056/nejmoa1603694.
Collins CL, Holberton JR, Barfield C, Davis PG. A randomized controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants. J Pediatr. 2013;162:949–54. https://doi.org/10.1016/j.jpeds.2012.11.016.
Kugelman A, Riskin A, Said W, Shoris I, Mor F, Bader D. A randomized pilot study comparing heated humidified high-flow nasal cannulae with NIPPV for RDS. Pediatr Pulmonol. 2015;50:576–83. https://doi.org/10.1002/ppul.23022.
Yengkhom R, Suryawanshi P, Gupta B, Deshpande S. Heated humidified high-flow nasal cannula vs. nasal continuous positive airway pressure for post-extubation respiratory support in preterm infants: a randomized controlled trial. J Trop Pediatr. 2020;67:82. https://doi.org/10.1093/tropej/fmaa082.
Öktem A, Yiğit Ş, Çelik HT, Yurdakök M. Comparison of four different non-invasive respiratory support techniques as primary respiratory support in preterm infants. Turk J Pediatr. 2021;63:23. https://doi.org/10.24953/turkjped.2021.01.003.
Fleeman N, Dundar Y, Shah PS, Shaw BN. Heated humidified high-flow nasal cannula for preterm infants: an updated systematic review and meta-analysis. Int J Technol Assess. 2019;35:298–306. https://doi.org/10.1017/s0266462319000424.
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O’Reilly, M., Schmölzer, G.M. (2023). Humidification During Non-invasive Respiratory Support of the Newborn. In: Esquinas, A.M. (eds) Humidification in the Intensive Care Unit. Springer, Cham. https://doi.org/10.1007/978-3-031-23953-3_20
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DOI: https://doi.org/10.1007/978-3-031-23953-3_20
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