Skip to main content

Chemistry or Biology: That Is the Question

  • Chapter
  • First Online:
Life in Science
  • 297 Accesses

Abstract

My first interest was for chemistry. I was fascinated by the possibility to make simple experiments with reagents commonly used in any house or readily available in a drugstore or in groceries such as baking soda, vinegar, bleach, ammonia, slaked lime, iodine, quicksilver. I also tried some electrochemical experiments with low voltage batteries and salt solutions obtaining the electrodeposition of copper, zinc or water electrolysis. Then I “discovered” organic chemistry with its almost infinite possibilities to generate new compounds with a marked interest for naturally occurring molecules like alkaloids, plant pigments and dyes, and natural flavors like terpenes, organic esters etc. Subsequently I realized that the most complex and sophisticated chemistry was invented by nature in the generation of living organisms. Living organisms in fact use organic chemistry to make an incredible variety of compounds and to construct the macromolecules (DNA, RNA, protein) and lipids that working together generate the complex phenomenon that we called “life”. At that point my choice was made and I decided to study biology with a focus for biochemistry and molecular biology and this opens the way to a long career in research laboratories and universities.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 64.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Alberghina L, Mariani L, Martegani E (1986) Cell cycle modelling. BioSystems 19:23–44

    Article  Google Scholar 

  • Baserga R (2006) Building a cathedral. Cancer Biol Ther 5:240–242

    Article  Google Scholar 

  • Broggi S, Martegani E, Colombo S (2013) Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae. Int J Biochem Cell Biol 45:384–394

    Article  Google Scholar 

  • Fleming A (1929) On the antibacterial action of cultures of a Penicillium with special reference to their use in the isolation of B. influenza. Br J Exp Pathol 10:226–236

    Google Scholar 

  • Jevons F (1965) The biochemical approach to life. Edizioni Scientifiche e Tecniche Mondadori

    Google Scholar 

  • Krebs HA, Johnson WA (1937) The role of citric acid in intermediate metabolism in animal tissues. Enzymologia 4:148–156

    Google Scholar 

  • Lander ES (2016) The heroes of CRISPR. Cell 164:18–28

    Article  Google Scholar 

  • Martegani E, Vanoni M, Baroni M (1984) Macromolecular syntheses in the cell cycle mutant cdc25 of budding yeast. Eur J Biochem 144:2015–2210

    Article  Google Scholar 

  • Martegani E, Baroni MD, Frascotti G, Alberghina L (1986) Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae. EMBO J 5:2363–2369

    Article  Google Scholar 

  • Martegani E, Vanoni M, Zippel R, Coccetti P, Brambilla R, Ferrari C, Sturani E, Alberghina L (1992) Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator. EMBO J 11:2151–2157

    Article  Google Scholar 

  • McClintock B (1951) Chromosome organization and genic expression. In: Cold spring harbor symposia on quantitative biology, Genes and Mutations, vol XVI, pp 13–48

    Google Scholar 

  • Peri F, Airoldi C, Colombo S, Martegani E et al (2005) Design, synthesis and biological evaluation of sugar-derived Ras inhibitors. ChemBioChem 6:1839–1848

    Article  Google Scholar 

  • Stephan P, Veugelers R, Wang J (2017) Reviewers are blinkered by bibliometrics. Nature 544:411–412

    Article  Google Scholar 

  • Watson J, Crick F (1953) Molecular structure of nuclei acids: a structure for deoxyribose nucleic acid. Nature 171:737–738

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Enzo Martegani .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Martegani, E. (2023). Chemistry or Biology: That Is the Question. In: Breviario, D., Tuszynski, J.A. (eds) Life in Science. Springer, Cham. https://doi.org/10.1007/978-3-031-23717-1_12

Download citation

Publish with us

Policies and ethics