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Mechanisms of Airway Allergies

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Airway diseases

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Abstract

Both allergic rhinitis (AR) and allergic asthma are disorders involving chronic atopic inflammation which affects the airway. The mechanism causing AR is the attachment of an allergenic epitope to specific IgE in an individual who has undergone sensitization. This then manifests symptomatically as a nasal discharge, blocked nose, pruritus, sternutation, and tiredness [1]. There are associations between AR and several other conditions, both atopic and nonatopic, notably asthma, allergic conjunctivitis, allergic eczema, and chronic rhinosinusitis (CRS). The features of asthma are a chronic inflammatory state, excessive production of mucus, edema, airway obstruction of varying severity, and weariness. Asthma does not consist of just one syndrome, and there are several phenotypic presentations, both pediatric and adult, with the most frequently noted phenotypes being the allergic and nonallergic types of asthma [2].

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Author information

Authors and Affiliations

  1. Department of Pulmonology, Harran University, Medical Faculty, Şanlıurfa, Turkey

    Hamdiye Turan

  2. Department of Pulmonology, Ağrı State Hospital, Ağrı, Turkey

    Dursun Erol Afşin

  3. Pulmonology Department, Celal Bayar University, Medical Faculty, Manisa, Turkey

    Arzu Yorgancıoğlu

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  1. Hamdiye Turan
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  2. Dursun Erol Afşin
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  3. Arzu Yorgancıoğlu
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Editor information

Editors and Affiliations

  1. Department of Otorhinolaryngology, Eskişehir Osmangazi University, Eskisehir, Türkiye

    Cemal Cingi

  2. Department of Pulmonology, Celal Bayar University, Manisa, Türkiye

    Arzu Yorgancıoğlu

  3. Department of Otorhinolaryngology, Kırıkkale University, Kırıkkale, Türkiye

    Nuray Bayar Muluk

  4. Federal University of Bahia School of Medicine and ProAR Foundation, Salvador - Bahia, Brazil

    Alvaro A. Cruz

Section Editor information

  1. Otorhinolaryngology Section, Dilber Private Clinic, İstanbul, Turkey

    Muhammet Dilber

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Turan, H., Afşin, D.E., Yorgancıoğlu, A. (2023). Mechanisms of Airway Allergies. In: Cingi, C., Yorgancıoğlu, A., Bayar Muluk, N., Cruz, A.A. (eds) Airway diseases. Springer, Cham. https://doi.org/10.1007/978-3-031-22483-6_42-1

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  • DOI: https://doi.org/10.1007/978-3-031-22483-6_42-1

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