Abstract
The main triggers of functional hypothalamic amenorrhoea are stress, weight loss, or excessive exercise, but the pathogenesis is not always immediately clear. This chapter highlights what is known about the pathophysiology of this form of menstrual dysfunction, as well as the steps for diagnostic evaluation, with a particular focus on less defined clinical situations as borderline energy deficiency, amenorrhoea that persists after weight recovery, and overlap of hypothalamic amenorrhoea with polycystic ovary syndrome.
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Bruni, V., Dei, M., Ambroggio, S. (2023). The New Forms of Functional Hypothalamic Amenorrhoea. In: Genazzani, A.R., Hirschberg, A.L., Genazzani, A.D., Nappi, R., Vujovic, S. (eds) Amenorrhea. ISGE Series. Springer, Cham. https://doi.org/10.1007/978-3-031-22378-5_4
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DOI: https://doi.org/10.1007/978-3-031-22378-5_4
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