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Chronicles of Hantaviruses: Foundations of Epidemiology and Ecology

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History of Arbovirology: Memories from the Field

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Abstract

The story of the hantaviruses is among the most exciting in all of virology. The disease now known as hemorrhagic fever with renal syndrome was likely present for decades in Asia. It gained attention of western medicine when United Nations soldiers suffered this new illness during the Korean Conflict. Through US Army sponsored research, Hantaan virus was identified as the cause and a link was born with the US military that continues to this day. Many discoveries were made by scientists at the US Army Medical Research Institute of Infectious Diseases while collaborating with experts worldwide. What was originally thought to be a single disease of Asia is today recognized as a complex of related infections found nearly worldwide. Here, we share our personal experiences conducting field studies on the hantaviruses, with special attention to Seoul virus that is found virtually worldwide where it exists in close association with its rodent host, Rattus norvegicus. It is not our goal to provide a comprehensive summary of the many breakthroughs made; rather, we hope to share the excitement and challenges we witnessed firsthand during this period of discovery as the scientific community came to better understand the complexity of the hantaviruses.

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Authors and Affiliations

  1. Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, USA

    James W. Le Duc

  2. Epidemiology of Microbial Diseases Department, Yale University School of Public Health, Yale University, New Haven, CT, USA

    James E. Childs

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  1. James W. Le Duc
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Correspondence to James W. Le Duc .

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Editors and Affiliations

  1. Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA

    Nikos Vasilakis

  2. School of Public Health, University at Albany, State University of New York, Albany, NY, USA

    Laura D. Kramer

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Le Duc, J.W., Childs, J.E. (2023). Chronicles of Hantaviruses: Foundations of Epidemiology and Ecology. In: Vasilakis, N., Kramer, L.D. (eds) History of Arbovirology: Memories from the Field. Springer, Cham. https://doi.org/10.1007/978-3-031-21999-3_7

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