Abstract
The article describes the results of detection of anti-mycobacterial and anti-leukemic antibodies in the blood serum samples of cows. Samples were obtained from tuberculin-responsive and tuberculin non-responsive as well as from BLV-infected and non-infected animals. Data are presented proving that anti-leukemic antibodies are found in more than 30 percent of samples obtained from animals that react to tuberculin. Antimycobacterial antibodies are found in more than 40 percent of samples that are positive in the immunodiffusion reaction. The experiments were carried out in three experimental groups of cows. In the first group, samples were positive for the immunodiffusion reaction and were obtained from cows that did not respond to tuberculin. In the second group, samples were negative in the reaction of immunodiffusion and were received from animals that respond to tuberculin. In the third group, samples were positive in the reaction of immunodiffusion and were obtained from tuberculin-responsive cows. Ten samples were taken from each group. The presented research results allow us to conclude about the possible determinant commonality of the antigens of the bovine leukemia virus and avian mycobacteria. The cause of tuberculin reactions in animals may well be infection with BLV. When carrying out diagnostic measures for leukemia and tuberculosis in cattle, when differentiating nonspecific tuberculin reactions, it is necessary to take into account the epizootic situation for these infections.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Avilés, C., Polvillo, O., Pena, F., Juarez, M., Martinez, A.L., Molina, A.: Associations between DGAT1, FABP4, LEP, RORC, and SCD1 gene polymorphisms and fat deposition in Spanish commercial beef. Anim. Biotechnol. 26(1), 40–44 (2015)
Chessa, S., Chiatti, C.G.: Development of a single nucleotide polymorphism genotyping microarray platform for the identification of bovine milk protein genetic polymorphisms. J. Dairy Sci. 90, 451–464 (2007). https://doi.org/10.3168/JDS.S0022-0302%2807%2972647-4
Gustavsson, F., et al.: Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey cows. J. Dairy Sci. 97, 3866–3877 (2014). https://doi.org/10.3168/jds.2013-7312
Konnai, S., Murata, S., Ohashi, K.: Immune exhaustion during Chronic Infections in Cattle. J. Vet. Med. Sci. 79(1), 1–5 (2017). https://doi.org/10.1292/jvms.16-0354
Lien, S., Kantanen, J., Olsaker, I.: Comparison of milk protein allele frequencies in Nordic cattle breeds. Anim. Genet. 30, 85–91 (1999). https://doi.org/10.1046/J.1365-2052.1999.00434.X
Miluchová, M., Gábor, M., Trakovická, A.: Analysis of genetic structure in Slovak Pinzgau cattle using five candidate genes related to milk production traits. Genetika 46, 865–875 (2014). https://doi.org/10.1046/J.1365-2052.1999.00434.X
Willems, L., Burny, A., Collete, D., Dangoisse, O.: Genetic determinants of bovine leukemia virus pathogenesis. AIDS Res. Hum. Retroviruses 16(16), 1787–1795 (2000). https://doi.org/10.1089/08892220050193326
Yakupov, T.R., et al.: Diagnostic role of circulating immune complexes during cow leukemia. Biosci. Biotechnol. Res. Commun. 13(15), 27–29 (2020)
Yakupov, T.R., Valiev, M.M., Zinnatov, F.F., Alimov, A.M., Galiullin, A.K., Hairullin, D.D., Papaev, R.M., Smolentsev, S.Y.: Features of humoral immunity in cows infected with the leukaemia virus. Int. J. Res. Pharm. Sci. 11(1), 290–293 (2020). https://doi.org/10.26452/ijrps.v11i1.1819
Zinnatov, F.F., Zinnatova, F.F., Volkov, A.H., Akhmetov, T.M., Alimov, A.M., Yakupov, T.R., Hairullin, D.D., Safina, N.Y.: Studying the association of polymorphic variants of lep, tg5, csn3, lgb genes with signs of dairy productivity of cattle. Int. J. Res. Pharm. Sci. 11(2), 1428–1432 (2020). https://doi.org/10.26452/ijrps.v11i2.2013
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Yakupov, T.R. et al. (2023). Immunological Aspects of Bovine Leukemia and Tuberculosis. In: Beskopylny, A., Shamtsyan, M., Artiukh, V. (eds) XV International Scientific Conference “INTERAGROMASH 2022”. INTERAGROMASH 2022. Lecture Notes in Networks and Systems, vol 575. Springer, Cham. https://doi.org/10.1007/978-3-031-21219-2_313
Download citation
DOI: https://doi.org/10.1007/978-3-031-21219-2_313
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-21218-5
Online ISBN: 978-3-031-21219-2
eBook Packages: EngineeringEngineering (R0)