Abstract
Endoscopic screening and surveillance of Barrett’s esophagus (BE) are limited to the small volume of tissue sampled by random biopsies, leaving a large area of metaplasia that may contain unidentified dysplasia. Technologies to better assess the mucosa and direct further examination or to better diagnose the severity of disease represent an evolution of the endoscopic surveillance of BE. Wide-area transepithelial sampling of the esophagus with computer-assisted three-dimensional analysis (WATS3D) and endoscopic microscopy including confocal laser endomicroscopy (CLE) or optical coherence tomography (OTC) may improve the ability to diagnose and manage patients with BE. In this chapter, we will review these emerging technologies, their application, and the clinical evidence behind their use.
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JSW recieves consulting fees from Boston Scientific. EMP receives honoraria from Becton Dickinson, Medtronic, Ovesco, Cook Biotech, Boston Scientific, Actuated Biomedical, Baxter, Wells Fargo, CMR Surgical, and royalties from Up-To-Date and Springer.
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Winder, J.S., Pauli, E.M. (2023). Barrett’s Esophagus Surveillance: WATS, Real-Time Endoscopic Microscopy. In: Kroh, M., Docimo Jr., S., El Djouzi, S., Shada, A., Reavis, K.M. (eds) The SAGES Manual Operating Through the Endoscope. Springer, Cham. https://doi.org/10.1007/978-3-031-21044-0_15
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