Skip to main content

Introduction to Infectious and Tuberculous Pleural Effusion

  • Chapter
  • First Online:
Practical Manual of Pleural Pathology
  • 158 Accesses

Abstract

Infectious and Tuberculous pleural effusion in this manual will be treated in two separate chapters, but a common introduction is required owing to the strong similarities they may present at the beginning on a clinical level.

The different types of pleural effusions of infectious aetiology are Parapneumonic effusions, Tuberculous pleural effusion and Atypical pleuritis (often opportunistic infections in immunosuppressed patients).

The problems that usually occur in the management of the infectious pathology of the pleura are that the isolation of pathogens is not easy, and that the microbiological tests are not always requested or are only partially requested. An important diagnostic step that unfortunately is neglected in many hospitals is that of the differential cell count in the pleural fluid, which in effusions of infectious origin plays a decisive role in distinguishing with excellent approximation the effusions of tuberculous origin from the others. For this reason, we believe that the differential cell count of the pleural fluid is mandatory.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Cohen M, Sahn SA. Resolution of pleural effusions. Chest. 2001;119(5):1547–62. https://doi.org/10.1378/chest.119.5.1547. PMID: 11348966.

    Article  CAS  PubMed  Google Scholar 

  2. Roper WH, Waring JJ. Primary serofibrinous pleural effusion in military personnel. Am Rev Tuberc. 1955;71(5):616–34. https://doi.org/10.1164/artpd.1955.71.5.616. PMID: 14361976.

    Article  CAS  PubMed  Google Scholar 

  3. Casalini AG, Cusmano F, Sverzellati N, Mori PA, Majori M. An undiagnosed pleural effusion with surprising consequences. Respir Med Case Rep. 2017;22:53–6. https://doi.org/10.1016/j.rmcr.2017.05.007. PMID: 28702335; PMCID: PMC5487223.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Zhan N, Guo Y, Tian S, Huang B, Tian X, Zou J, Xiong Q, Tang D, Zhang L, Dong W. Clinical characteristics of COVID-19 complicated with pleural effusion. BMC Infect Dis. 2021;21(1):176. https://doi.org/10.1186/s12879-021-05856-8. PMID: 33588779; PMCID: PMC7883764.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Davies HE, Davies RJ, Davies CW, BTS Pleural Disease Guideline Group. Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010;65(Suppl 2):41–53. https://doi.org/10.1136/thx.2010.137000. PMID: 20696693.

    Article  Google Scholar 

  6. Antony VB, Godbey SW, Kunkel SL, Hott JW, Hartman DL, Burdick MD, Strieter RM. Recruitment of inflammatory cells to the pleural space. Chemotactic cytokines, IL-8, and monocyte chemotactic peptide-1 in human pleural fluids. J Immunol. 1993;151(12):7216–23. PMID: 8258721.

    Article  CAS  PubMed  Google Scholar 

  7. Spriggs AI, Boddington MM. The cytology of effusions. New York: Grune & Stratton; 1968. p. 12–40.

    Book  Google Scholar 

  8. Jeon D. Tuberculous pleurisy: an update. Tuberc Respir Dis. 2014;76(4):153–9. https://doi.org/10.4046/trd.2014.76.4.153. Epub 2014 Apr 25. PMID: 24851127; PMCID: PMC4021261.

    Article  Google Scholar 

  9. Valdés L, San José ME, Pose A, Gude F, González-Barcala FJ, Alvarez-Dobaño JM, Sahn SA. Diagnosing tuberculous pleural effusion using clinical data and pleural fluid analysis A study of patients less than 40 years-old in an area with a high incidence of tuberculosis. Respir Med. 2010;104(8):1211–7. https://doi.org/10.1016/j.rmed.2010.02.025. Epub 2010 Mar 26. PMID: 20347287.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Casalini, A.G. (2023). Introduction to Infectious and Tuberculous Pleural Effusion. In: Casalini, A.G. (eds) Practical Manual of Pleural Pathology. Springer, Cham. https://doi.org/10.1007/978-3-031-20312-1_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-20312-1_7

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-20311-4

  • Online ISBN: 978-3-031-20312-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics