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Cyclic Vomiting Syndrome, Dumping, and Marijuana-Induced Hyperemesis Syndrome

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The AFS Textbook of Foregut Disease

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Abstract

Cyclic vomiting syndrome (CVS) and marijuana-induced hyperemesis referred to as cannabinoid hyperemesis syndrome (CHS) are characterized by recurrent episodes of nausea and vomiting. This chapter addresses salient features of CVS, CHS, and abnormalities in gastric emptying/dumping syndrome. CHS is thought to be a subset of CVS and is related to chronic cannabis use concurrent with increased legalization of cannabis use. We discuss the role of cannabinoids in hyperemesis and highlight problems with high-potency cannabis products. The management of CVS and CHS is reviewed based on recent guidelines by the American Neurogastroenterology and Motility Society (ANMS) and the Cyclic Vomiting Syndrome Association (CVSA). Abnormalities in gastric emptying in CVS and CHS are also discussed and are likely epiphenomenon without any correlation with symptoms. There are significant gaps in knowledge about these disorders, which warrant further research to better understand the pathophysiology of these disorders.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA

    Thangam Venkatesan

  2. Division of Gastroenterology and Hepatology, University of Michigan Health System, Ann Arbor, MI, USA

    William L. Hasler

Authors
  1. Thangam Venkatesan
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  2. William L. Hasler
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Corresponding author

Correspondence to Thangam Venkatesan .

Editor information

Editors and Affiliations

  1. University of California, Irvine, Orange, CA, USA

    Ninh T. Nguyen

  2. Department of Gastroenterology & Hepatology, Stanford Digestive Health Clinic, Redwood City, CA, USA

    John O. Clarke

  3. Keck School of Medicine at USC, Los Angeles, CA, USA

    John C. Lipham

  4. Digestive Health Institute, University of California, Irvine, Orange, CA, USA

    Kenneth J. Chang

  5. Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York City, NY, USA

    Felice Schnoll-Sussman

  6. Institute of Esophageal & Reflux Surgery, Englewood, CO, USA

    Reginald C.W. Bell

  7. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

    Peter J. Kahrilas

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Venkatesan, T., Hasler, W.L. (2023). Cyclic Vomiting Syndrome, Dumping, and Marijuana-Induced Hyperemesis Syndrome. In: Nguyen, N.T., et al. The AFS Textbook of Foregut Disease. Springer, Cham. https://doi.org/10.1007/978-3-031-19671-3_45

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  • DOI: https://doi.org/10.1007/978-3-031-19671-3_45

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-19670-6

  • Online ISBN: 978-3-031-19671-3

  • eBook Packages: MedicineMedicine (R0)

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