Skip to main content

The High-Risk Pediatric Surgical Patient

  • Chapter
  • First Online:
The High-risk Surgical Patient

Abstract

With the advancements in medical therapies, pediatric patients with highly complex medical conditions are increasingly presenting for surgery and other procedures such as medical imaging that require general anesthesia. The interplay of this vulnerable patient population’s comorbidities and the intrinsic surgical risk puts them at a higher risk for perioperative morbidity and mortality. Multiple risk scores have been developed to identify patients at risk of mortality and morbidity. Identifying these patients allows for adequate case planning, expert staffing, and appropriate resource allocation with the objective of decreasing perioperative morbidity and improving post-operative outcomes.

This chapter will review the risk factors and summarize perioperative risk scores. It will also describe in detail subsets of high-risk patients with emphasis on preoperative multidisciplinary care and perioperative optimization.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Flick RP, Sprung J, Harrison TE, Gleich SJ, Schroeder DR, Hanson AC, et al. Perioperative cardiac arrests in children between 1988 and 2005 at a tertiary referral center: a study of 92,881 patients. Anesthesiology. 2007;106(2):226–37; quiz 413–4.

    PubMed  Google Scholar 

  2. Hoffman GM. Outcomes of pediatric anesthesia. Semin Pediatr Surg. 2008;17(2):141–51.

    PubMed  Google Scholar 

  3. Kawashima Y, Takahashi S, Suzuki M, Morita K, Irita K, Iwao Y, et al. Anesthesia-related mortality and morbidity over a 5-year period in 2,363,038 patients in Japan. Acta Anaesthesiol Scand. 2003;47(7):809–17.

    CAS  PubMed  Google Scholar 

  4. Gobbo Braz L, Braz JR, Modolo NS, Do Nascimento P, Brushi BA, Raquel de Carvalho L. Perioperative cardiac arrest and its mortality in children. A 9-year survey in a Brazilian tertiary teaching hospital. Paediatr Anaesth. 2006;16(8):860–6.

    PubMed  Google Scholar 

  5. Bonasso PC, Dassinger MS, Ryan ML, Gowen MS, Burford JM, Smith SD. 24-hour and 30-day perioperative mortality in pediatric surgery. J Pediatr Surg. 2019;54(4):628–30.

    PubMed  Google Scholar 

  6. Kraemer K, Cohen ME, Liu Y, Barnhart DC, Rangel SJ, Saito JM, et al. Development and evaluation of the American College of Surgeons NSQIP pediatric surgical risk calculator. J Am Coll Surg. 2016;223(5):685–93.

    PubMed  Google Scholar 

  7. Nasr VG, DiNardo JA, Faraoni D. Development of a pediatric risk assessment score to predict perioperative mortality in children undergoing noncardiac surgery. Anesth Analg. 2017;124(5):1514–9.

    CAS  PubMed  Google Scholar 

  8. Nasr VG, Staffa SJ, Zurakowski D, DiNardo JA, Faraoni D. Pediatric risk stratification is improved by integrating both patient comorbidities and intrinsic surgical risk. Anesthesiology. 2019;130(6):971–80.

    PubMed  Google Scholar 

  9. van der Griend BF, Lister NA, McKenzie IM, Martin N, Ragg PG, Sheppard SJ, et al. Postoperative mortality in children after 101,885 anesthetics at a tertiary pediatric hospital. Anesth Analg. 2011;112(6):1440–7.

    PubMed  Google Scholar 

  10. Berry JG, Johnson C, Crofton C, Staffa SJ, DiTillio M, Leahy I, et al. Predicting postoperative physiologic decline after surgery. Pediatrics. 2019;143(4):e20182042.

    PubMed  Google Scholar 

  11. Liu JB, Liu Y, Cohen ME, Ko CY, Sweitzer BJ. Defining the intrinsic cardiac risks of operations to improve preoperative cardiac risk assessments. Anesthesiology. 2018;128(2):283–92.

    PubMed  Google Scholar 

  12. Habre W, Disma N, Virag K, Becke K, Hansen TG, Johr M, et al. Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe. Lancet Respir Med. 2017;5(5):412–25.

    PubMed  Google Scholar 

  13. Lee C, Mason L. Complications in paediatric anaesthesia. Curr Opin Anaesthesiol. 2006;19(3):262–7.

    PubMed  Google Scholar 

  14. Nasr VG, Valencia E, Staffa SJ, Faraoni D, DiNardo JA, Berry JG, et al. Comprehensive risk assessment of morbidity in pediatric patients undergoing noncardiac surgery: an institutional experience. Anesth Analg. 2020;131(5):1607–15.

    PubMed  Google Scholar 

  15. Morray JP, Geiduschek JM, Caplan RA, Posner KL, Gild WM, Cheney FW. A comparison of pediatric and adult anesthesia closed malpractice claims. Anesthesiology. 1993;78(3):461–7.

    CAS  PubMed  Google Scholar 

  16. Morray JP, Geiduschek JM, Ramamoorthy C, Haberkern CM, Hackel A, Caplan RA, et al. Anesthesia-related cardiac arrest in children: initial findings of the pediatric perioperative cardiac arrest (POCA) registry. Anesthesiology. 2000;93(1):6–14.

    CAS  PubMed  Google Scholar 

  17. Kurth CD, Tyler D, Heitmiller E, Tosone SR, Martin L, Deshpande JK. National pediatric anesthesia safety quality improvement program in the United States. Anesth Analg. 2014;119(1):112–21.

    CAS  PubMed  Google Scholar 

  18. Bharti N, Batra YK, Kaur H. Paediatric perioperative cardiac arrest and its mortality: database of a 60-month period from a tertiary care paediatric Centre. Eur J Anaesthesiol. 2009;26(6):490–5.

    PubMed  Google Scholar 

  19. Bhananker SM, Ramamoorthy C, Geiduschek JM, Posner KL, Domino KB, Haberkern CM, et al. Anesthesia-related cardiac arrest in children: update from the pediatric perioperative cardiac arrest registry. Anesth Analg. 2007;105(2):344–50.

    PubMed  Google Scholar 

  20. Jimenez N, Posner KL, Cheney FW, Caplan RA, Lee LA, Domino KB. An update on pediatric anesthesia liability: a closed claims analysis. Anesth Analg. 2007;104(1):147–53.

    PubMed  Google Scholar 

  21. Tait AR, Malviya S, Voepel-Lewis T, Munro HM, Seiwert M, Pandit UA. Risk factors for perioperative adverse respiratory events in children with upper respiratory tract infections. Anesthesiology. 2001;95(2):299–306.

    CAS  PubMed  Google Scholar 

  22. Fiadjoe JE, Nishisaki A, Jagannathan N, Hunyady AI, Greenberg RS, Reynolds PI, et al. Airway management complications in children with difficult tracheal intubation from the pediatric difficult intubation (PeDI) registry: a prospective cohort analysis. Lancet Respir Med. 2016;4(1):37–48.

    PubMed  Google Scholar 

  23. Schleelein LE, Vincent AM, Jawad AF, Pruitt EY, Kreher GD, Rehman MA, et al. Pediatric perioperative adverse events requiring rapid response: a retrospective case-control study. Paediatr Anaesth. 2016;26(7):734–41.

    PubMed  Google Scholar 

  24. Christensen RE, Haydar B, Voepel-Lewis TD. Pediatric cardiopulmonary arrest in the Postanesthesia care unit, rare but preventable: analysis of data from wake up safe, the pediatric anesthesia quality improvement initiative. Anesth Analg. 2017;124(4):1231–6.

    PubMed  Google Scholar 

  25. Murat I, Constant I, Maud’huy H. Perioperative anaesthetic morbidity in children: a database of 24,165 anaesthetics over a 30-month period. Paediatr Anaesth. 2004;14(2):158–66.

    PubMed  Google Scholar 

  26. American Society of Anesthesiologists. ASA physical status classification system. https://www.asahq.org/standards-and-guidelines/asa-physical-status-classification-system

  27. Horvath B, Kloesel B, Todd MM, Cole DJ, Prielipp RC. The evolution, current value, and future of the American Society of Anesthesiologists Physical Status Classification System. Anesthesiology. 2021;135(5):904–19.

    PubMed  Google Scholar 

  28. Aplin S, Baines D, Lima JDE. Use of the ASA physical status grading system in pediatric practice. Paediatr Anaesth. 2007;17(3):216–22.

    PubMed  Google Scholar 

  29. Ranta S, Hynynen M, Tammisto T. A survey of the ASA physical status classification: significant variation in allocation among Finnish anaesthesiologists. Acta Anaesthesiol Scand. 1997;41(5):629–32.

    CAS  PubMed  Google Scholar 

  30. Valencia E, Staffa SJ, Faraoni D, DiNardo JA, Nasr VG. Prospective external validation of the pediatric risk assessment score in predicting perioperative mortality in children undergoing noncardiac surgery. Anesth Analg. 2019;129(4):1014–20.

    PubMed  Google Scholar 

  31. Jacqueline R, Malviya S, Burke C, Reynolds P. An assessment of interrater reliability of the ASA physical status classification in pediatric surgical patients. Paediatr Anaesth. 2006;16(9):928–31.

    PubMed  Google Scholar 

  32. Ferrari L, Leahy I, Staffa SJ, Berry JG. The pediatric-specific American Society of Anesthesiologists Physical Status Score: a multicenter study. Anesth Analg. 2021;132(3):807–17.

    PubMed  Google Scholar 

  33. Faraoni D, Vo D, Nasr VG, DiNardo JA. Development and validation of a risk stratification score for children with congenital heart disease undergoing noncardiac surgery. Anesth Analg. 2016;123(4):824–30.

    PubMed  Google Scholar 

  34. User guide for the 2014 ACS NSQIP participant use data file (PUF): American College of Surgeons, National Surgical Quality Improvement Program; October 2015.

    Google Scholar 

  35. Chawanpaiboon S, Vogel JP, Moller AB, Lumbiganon P, Petzold M, Hogan D, et al. Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health. 2019;7(1):e37–46.

    PubMed  Google Scholar 

  36. Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA. 2015;314(10):1039–51.

    CAS  PubMed  PubMed Central  Google Scholar 

  37. Saigal S, Doyle LW. An overview of mortality and sequelae of preterm birth from infancy to adulthood. Lancet. 2008;371(9608):261–9.

    PubMed  Google Scholar 

  38. Lillehei CW, Gauvreau K, Jenkins KJ. Risk adjustment for neonatal surgery: a method for comparison of in-hospital mortality. Pediatrics. 2012;130(3):e568–74.

    PubMed  Google Scholar 

  39. Michelet D, Brasher C, Kaddour HB, Diallo T, Abdat R, Malbezin S, et al. Postoperative complications following neonatal and infant surgery: common events and predictive factors. Anaesth Crit Care Pain Med. 2017;36(3):163–9.

    PubMed  Google Scholar 

  40. Boat AC, Sadhasivam S, Loepke AW, Kurth CD. Outcome for the extremely premature neonate: how far do we push the edge? Paediatr Anaesth. 2011;21(7):765–70.

    PubMed  Google Scholar 

  41. McCann ME, Lee JK, Inder T. Beyond anesthesia toxicity: anesthetic considerations to lessen the risk of neonatal neurological injury. Anesth Analg. 2019;129(5):1354–64.

    CAS  PubMed  PubMed Central  Google Scholar 

  42. McCann ME, Soriano SG. General anesthetics in pediatric anesthesia: influences on the developing brain. Curr Drug Targets. 2012;13(7):944–51.

    CAS  PubMed  PubMed Central  Google Scholar 

  43. McCann ME, Schouten AN. Beyond survival; influences of blood pressure, cerebral perfusion and anesthesia on neurodevelopment. Paediatr Anaesth. 2014;24(1):68–73.

    PubMed  Google Scholar 

  44. Disma N, Veyckemans F, Virag K, Hansen TG, Becke K, Harlet P, et al. Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). Br J Anaesth. 2021;126(6):1157–72.

    PubMed  Google Scholar 

  45. Kurth CD, Cote CJ. Postoperative apnea in former preterm infants: general anesthesia or spinal anesthesia—do we have an answer? Anesthesiology. 2015;123(1):15–7.

    PubMed  Google Scholar 

  46. Cote CJ, Zaslavsky A, Downes JJ, Kurth CD, Welborn LG, Warner LO, et al. Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. Anesthesiology. 1995;82(4):809–22.

    CAS  PubMed  Google Scholar 

  47. Davidson AJ, Morton NS, Arnup SJ, de Graaff JC, Disma N, Withington DE, et al. Apnea after awake regional and general anesthesia in infants: the general anesthesia compared to spinal anesthesia study—comparing apnea and neurodevelopmental outcomes, a randomized controlled trial. Anesthesiology. 2015;123(1):38–54.

    PubMed  Google Scholar 

  48. Somri M, Gaitini L, Vaida S, Collins G, Sabo E, Mogilner G. Postoperative outcome in high-risk infants undergoing herniorrhaphy: comparison between spinal and general anaesthesia. Anaesthesia. 1998;53(8):762–6.

    CAS  PubMed  Google Scholar 

  49. Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002;39(12):1890–900.

    PubMed  Google Scholar 

  50. Brown ML, DiNardo JA, Nasr VG. Anesthesia in pediatric patients with congenital heart disease undergoing noncardiac surgery: defining the risk. J Cardiothorac Vasc Anesth. 2020;34(2):470–8.

    PubMed  Google Scholar 

  51. Nasr VG, Staffa SJ, Faraoni D, DiNardo JA. Trends in mortality rate in patients with congenital heart disease undergoing noncardiac surgical procedures at children’s hospitals. Sci Rep. 2021;11(1):1543.

    CAS  PubMed  PubMed Central  Google Scholar 

  52. Sulkowski JP, Cooper JN, McConnell PI, Pasquali SK, Shah SS, Minneci PC, et al. Variability in noncardiac surgical procedures in children with congenital heart disease. J Pediatr Surg. 2014;49(11):1564–9.

    PubMed  PubMed Central  Google Scholar 

  53. Baum VC, Barton DM, Gutgesell HP. Influence of congenital heart disease on mortality after noncardiac surgery in hospitalized children. Pediatrics. 2000;105(2):332–5.

    CAS  PubMed  Google Scholar 

  54. Faraoni D, Zurakowski D, Vo D, Goobie SM, Yuki K, Brown ML, et al. Post-operative outcomes in children with and without congenital heart disease undergoing noncardiac surgery. J Am Coll Cardiol. 2016;67(7):793–801.

    PubMed  Google Scholar 

  55. Ramamoorthy C, Haberkern CM, Bhananker SM, Domino KB, Posner KL, Campos JS, et al. Anesthesia-related cardiac arrest in children with heart disease: data from the pediatric perioperative cardiac arrest (POCA) registry. Anesth Analg. 2010;110(5):1376–82.

    CAS  PubMed  Google Scholar 

  56. Faraoni D, Zou X, DiNardo JA, Nasr VG. Integration of the intrinsic surgical risk with patient comorbidities and severity of congenital cardiac disease does not improve risk stratification in children undergoing noncardiac surgery. Anesth Analg. 2020;131(4):1083–9.

    CAS  PubMed  Google Scholar 

  57. Miller R, Tumin D, Tobias JD, McKee C. Estimating surgical risk in younger and older children with congenital heart disease. J Surg Res. 2018;232:298–307.

    PubMed  Google Scholar 

  58. Torres A Jr, DiLiberti J, Pearl RH, Wohrley J, Raff GW, Bysani GK, et al. Noncardiac surgery in children with hypoplastic left heart syndrome. J Pediatr Surg. 2002;37(10):1399–403.

    PubMed  Google Scholar 

  59. Yuki K, Koutsogiannaki S, Lee S, DiNardo JA. Unanticipated hospital admission in pediatric patients with congenital heart disease undergoing ambulatory noncardiac surgical procedures. Paediatr Anaesth. 2018;28(7):607–11.

    PubMed  Google Scholar 

  60. Viviane G. Nasr, DiNardo JA. Single-ventricle lesions. The pediatric cardiac anesthesia handbook. 2017. p. 161-80. Wiley Hoboken, NJ

    Google Scholar 

  61. Burch TM, McGowan FX Jr, Kussman BD, Powell AJ, DiNardo JA. Congenital supravalvular aortic stenosis and sudden death associated with anesthesia: what’s the mystery? Anesth Analg. 2008;107(6):1848–54.

    PubMed  Google Scholar 

  62. Matisoff AJ, Olivieri L, Schwartz JM, Deutsch N. Risk assessment and anesthetic management of patients with Williams syndrome: a comprehensive review. Paediatr Anaesth. 2015;25(12):1207–15.

    PubMed  Google Scholar 

  63. Makavos G, Kappaairis C, Tselegkidi ME, Karamitsos T, Rigopoulos AG, Noutsias M, et al. Hypertrophic cardiomyopathy: an updated review on diagnosis, prognosis, and treatment. Heart Fail Rev. 2019;24(4):439–59.

    PubMed  Google Scholar 

  64. Williams GD, Hammer GB. Cardiomyopathy in childhood. Curr Opin Anaesthesiol. 2011;24(3):289–300.

    PubMed  Google Scholar 

  65. Navaratnam M, Maeda K, Hollander SA. Pediatric ventricular assist devices: bridge to a new era of perioperative care. Paediatr Anaesth. 2019;29(5):506–18.

    PubMed  Google Scholar 

  66. Gorbea M. A review of physiologic considerations and challenges in pediatric patients with failing single- ventricle physiology undergoing ventricular assist device placement. J Cardiothorac Vasc Anesth. 2022;36(6):1756–70.

    PubMed  Google Scholar 

  67. Rawat RS. Congenital syndromes affecting heart and airway alike. Ann Card Anaesth. 2017;20(4):393–4.

    PubMed  PubMed Central  Google Scholar 

  68. Foz C, Peyton J, Staffa SJ, Kovatsis P, Park R, DiNardo JA, et al. Airway abnormalities in patients with congenital heart disease: incidence and associated factors. J Cardiothorac Vasc Anesth. 2021;35(1):139–44.

    PubMed  Google Scholar 

  69. Butler MG, Hayes BG, Hathaway MM, Begleiter ML. Specific genetic diseases at risk for sedation/anesthesia complications. Anesth Analg. 2000;91(4):837–55.

    CAS  PubMed  PubMed Central  Google Scholar 

  70. Bertrand P, Navarro H, Caussade S, Holmgren N, Sanchez I. Airway anomalies in children with down syndrome: endoscopic findings. Pediatr Pulmonol. 2003;36(2):137–41.

    PubMed  Google Scholar 

  71. Huang RY, Shapiro NL. Structural airway anomalies in patients with DiGeorge syndrome: a current review. Am J Otolaryngol. 2000;21(5):326–30.

    CAS  PubMed  Google Scholar 

  72. Sacca R, Zur KB, Crowley TB, Zackai EH, Valverde KD, McDonald-McGinn DM. Association of airway abnormalities with 22q11.2 deletion syndrome. Int J Pediatr Otorhinolaryngol. 2017;96:11–4.

    PubMed  Google Scholar 

  73. Odegard KC, Vincent R, Baijal R, Daves S, Gray R, Javois A, et al. SCAI/CCAS/SPA expert consensus statement for anesthesia and sedation practice: recommendations for patients undergoing diagnostic and therapeutic procedures in the pediatric and congenital cardiac catheterization laboratory. Catheter Cardiovasc Interv. 2016;88(6):912–22.

    PubMed  Google Scholar 

  74. Wadia RS, Bernier ML, Diaz-Rodriguez NM, Goswami DK, Nyhan SM, Steppan J. Update on perioperative pediatric pulmonary hypertension management. J Cardiothorac Vasc Anesth. 2022;36(3):667–76.

    PubMed  Google Scholar 

  75. Heinrich D, Diewitz M. Pulmonary hypertension: definition, etiology, physiopathology and clinical picture. Med Welt. 1972;23(2):45–9.

    CAS  PubMed  Google Scholar 

  76. Rosenzweig EB, Abman SH, Adatia I, Beghetti M, Bonnet D, Haworth S, et al. Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management. Eur Respir J. 2019;53(1):1801916.

    PubMed  PubMed Central  Google Scholar 

  77. Bernier ML, Jacob AI, Collaco JM, McGrath-Morrow SA, Romer LH, Unegbu CC. Perioperative events in children with pulmonary hypertension undergoing non-cardiac procedures. Pulm Circ. 2018;8(1):2045893217738143.

    PubMed  Google Scholar 

  78. Balkin EM, Olson ED, Robertson L, Adatia I, Fineman JR, Keller RL. Change in pediatric functional classification during treatment and morbidity and mortality in children with pulmonary hypertension. Pediatr Cardiol. 2016;37(4):756–64.

    PubMed  PubMed Central  Google Scholar 

  79. Taylor CJ, Derrick G, McEwan A, Haworth SG, Sury MR. Risk of cardiac catheterization under anaesthesia in children with pulmonary hypertension. Br J Anaesth. 2007;98(5):657–61.

    CAS  PubMed  Google Scholar 

  80. Blaise G, Langleben D, Hubert B. Pulmonary arterial hypertension: pathophysiology and anesthetic approach. Anesthesiology. 2003;99(6):1415–32.

    PubMed  Google Scholar 

  81. Warner MA, Lunn RJ, O’Leary PW, Schroeder DR. Outcomes of noncardiac surgical procedures in children and adults with congenital heart disease. Mayo Perioperative Outcomes Group. Mayo Clin Proc. 1998;73(8):728–34.

    CAS  PubMed  Google Scholar 

  82. Carmosino MJ, Friesen RH, Doran A, Ivy DD. Perioperative complications in children with pulmonary hypertension undergoing noncardiac surgery or cardiac catheterization. Anesth Analg. 2007;104(3):521–7.

    PubMed  PubMed Central  Google Scholar 

  83. Latham GJ, Yung D. Current understanding and perioperative management of pediatric pulmonary hypertension. Paediatr Anaesth. 2019;29(5):441–56.

    PubMed  Google Scholar 

  84. O’Byrne ML, Glatz AC, Hanna BD, Shinohara RT, Gillespie MJ, Dori Y, et al. Predictors of catastrophic adverse outcomes in children with pulmonary hypertension undergoing cardiac catheterization: a multi-institutional analysis from the pediatric health information systems database. J Am Coll Cardiol. 2015;66(11):1261–9.

    PubMed  PubMed Central  Google Scholar 

  85. Taylor K, Moulton D, Zhao XY, Laussen P. The impact of targeted therapies for pulmonary hypertension on pediatric intraoperative morbidity or mortality. Anesth Analg. 2015;120(2):420–6.

    CAS  PubMed  Google Scholar 

  86. Parnis SJ, Barker DS, Van Der Walt JH. Clinical predictors of anaesthetic complications in children with respiratory tract infections. Paediatr Anaesth. 2001;11(1):29–40.

    CAS  PubMed  Google Scholar 

  87. Tait AR, Knight PR. The effects of general anesthesia on upper respiratory tract infections in children. Anesthesiology. 1987;67(6):930–5.

    CAS  PubMed  Google Scholar 

  88. Elwood T, Bailey K. The pediatric patient and upper respiratory infections. Best Pract Res Clin Anaesthesiol. 2005;19(1):35–46.

    PubMed  Google Scholar 

  89. Flick RP, Wilder RT, Pieper SF, van Koeverden K, Ellison KM, Marienau ME, et al. Risk factors for laryngospasm in children during general anesthesia. Paediatr Anaesth. 2008;18(4):289–96.

    PubMed  Google Scholar 

  90. Bordet F, Allaouchiche B, Lansiaux S, Combet S, Pouyau A, Taylor P, et al. Risk factors for airway complications during general anaesthesia in paediatric patients. Paediatr Anaesth. 2002;12(9):762–9.

    PubMed  Google Scholar 

  91. Zhang S, Ding S, Cai M, Bai J, Zhang M, Huang Y, et al. Impact of upper respiratory tract infections on perioperative outcomes of children undergoing therapeutic cardiac catheterisation. Acta Anaesthesiol Scand. 2018;62(7):915–23.

    CAS  PubMed  Google Scholar 

  92. Niermeyer WL, Ball J, Worobetz N, Bourgeois T, Onwuka A, Burrier C, et al. Respiratory viral panels and pediatric airway evaluation: the role of testing for upper respiratory infections to stratify perioperative risk. Int J Pediatr Otorhinolaryngol. 2020;134:110057.

    PubMed  PubMed Central  Google Scholar 

  93. Cote CJ. The upper respiratory tract infection (URI) dilemma: fear of a complication or litigation? Anesthesiology. 2001;95(2):283–5.

    CAS  PubMed  Google Scholar 

  94. von Ungern-Sternberg BS, Boda K, Chambers NA, Rebmann C, Johnson C, Sly PD, et al. Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study. Lancet. 2010;376(9743):773–83.

    Google Scholar 

  95. Drake-Brockman TF, Ramgolam A, Zhang G, Hall GL, von Ungern-Sternberg BS. The effect of endotracheal tubes versus laryngeal mask airways on perioperative respiratory adverse events in infants: a randomised controlled trial. Lancet. 2017;389(10070):701–8.

    PubMed  Google Scholar 

  96. Gharaei B, Jafari A, Poor Zamany M, Kamranmanesh M, Aghamohammadi H, Roodneshin F, et al. Topical versus intravenous Lidocaine in children with upper respiratory infection undergoing anesthesia: a randomized, double blind, clinical trial. Anesth Pain Med. 2015;5(4):e23501.

    PubMed  PubMed Central  Google Scholar 

  97. Lema GF, Berhe YW, Gebrezgi AH, Getu AA. Evidence-based perioperative management of a child with upper respiratory tract infections (URTIs) undergoing elective surgery: a systematic review. Int J Surg Open. 2018;12:17–24.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Viviane G. Nasr .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Foz, C., DiNardo, J.A., Nasr, V.G. (2023). The High-Risk Pediatric Surgical Patient. In: Aseni, P., Grande, A.M., Leppäniemi, A., Chiara, O. (eds) The High-risk Surgical Patient. Springer, Cham. https://doi.org/10.1007/978-3-031-17273-1_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-17273-1_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-17272-4

  • Online ISBN: 978-3-031-17273-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics