Abstract
The COVID-19 pandemic remains a concrete challenge, especially in communities and rural areas where health resources are scarce. We recently developed several classifiers, useful to predict safe discharge, disease severity, and mortality risk from COVID-19, fed by routine analyses collected in the Emergency Department. In this paper, we discuss a system, made up of an app and a server, that enables doctors to use these models during the management of COVID-19 patients. The app has been developed involving the doctors since the early phases of the app design, then revised in the light of two usability cycles. We report its main features and its ease of use. So far, it has been used during the fourth wave, producing accurate results with patients that did not complete the vaccination protocol (i.e., up to the second dose).
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Notes
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P/F (PaO\(_2\)/FIO\(_2\)) = Oxygenation Index, NLR = Neutrophil-to-Lymphocyte Ratio, PLR = Platelet-to-Lymphocyte Ratio.
References
Andrews N et al (2022) Duration of protection against mild and severe disease by COVID-19 vaccines. N Engl J Med 386(4):340–350. https://doi.org/10.1056/NEJMOA2115481
Bath PA (2008) Health informatics: current issues and challenges. J Inf Sci 34(4):501–518. https://doi.org/10.1177/0165551508092267
Booth AL, Abels E, McCaffrey P (2021) Development of a prognostic model for mortality in COVID-19 infection using machine learning. Mod Pathol 34(3):522–531. an official journal of the United States and Canadian Academy of Pathology, Inc. https://doi.org/10.1038/S41379-020-00700-X
Breiman L (2001) Random forests. Mach Learn 45(1):5–32. https://doi.org/10.1023/A:1010933404324
Breiman L, Friedman JH, Olshen RA, Stone CJ (2017) Classification and Regression Trees. CRC Press, Boca Raton. https://doi.org/10.1201/9781315139470
Van Buuren S, Groothuis-Oudshoorn K (2011) MICE: multivariate imputation by chained equations in R. J Stat Softw 45(3):1–67. https://doi.org/10.18637/JSS.V045.I03
Casano N et al (2022) Application of machine learning approach in Emergency Department to support clinical decision making for SARS-CoV-2 infected patients. Submitted manuscript, under review
Chamoso P, De La Prieta F, Eibenstein A, Santos-Santos D, Tizio A, Vittorini P (2017) A device supporting the self management of tinnitus. In: Rojas I, Ortuño F (eds) IWBBIO 2017, vol 10209. LNCS. Springer, Cham, pp 399–410. https://doi.org/10.1007/978-3-319-56154-7_36
Chen T, Guestrin C (2016) XGBoost: a scalable tree boosting system. In: Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, pp 785–794. ACM, New York, NY, USA. https://doi.org/10.1145/2939672
Efron B (1983) Estimating the error rate of a prediction rule: improvement on cross-validation. J Am Stat Assoc 78(382):316–331. https://doi.org/10.1080/01621459.1983.10477973
He J, Baxter SL, Xu J, Xu J, Zhou X, Zhang K (2019) The practical implementation of artificial intelligence technologies in medicine. Nat Med 25(1):30–36. https://doi.org/10.1038/s41591-018-0307-0
Jimenez-Solem E et al (2021) Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients. Sci Rep 11(1):1–12. 2021 11:1. https://doi.org/10.1038/s41598-021-81844-x
Kearns P et al (2021) Examining the immunological effects of COVID-19 vaccination in patients with conditions potentially leading to diminished immune response capacity–the OCTAVE trial. SSRN Electron J. https://doi.org/10.2139/SSRN.3910058
Lipsitch M, Krammer F, Regev-Yochay G, Lustig Y., Balicer RD (2021) SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact. Nat Rev Immunol 22(1):57–65. 2021 22:1. https://doi.org/10.1038/s41577-021-00662-4
Liu Y, et al (2020) A COVID-19 risk assessment decision support system for general practitioners: design and development study. J Med Internet Res 22(6). https://doi.org/10.2196/19786
Mao JY, Vredenburg K, Smith PW, Carey T (2005) The state of user-centered design practice. Commun ACM 48(3):105–109. https://doi.org/10.1145/1047671.1047677
Mathieu E et al (2021) A global database of COVID-19 vaccinations. Nat Hum Behav 5(7):947–953. 2021 5:7. https://doi.org/10.1038/s41562-021-01122-8
McRae MP et al (2020) Managing COVID-19 with a clinical decision support tool in a community health network: algorithm development and validation. J Med Internet Res 22(8):e22033. https://doi.org/10.2196/22033
R Core Team: R (2018) A Language and Environment for Statistical Computing. https://www.R-project.org/
Richardson L, Ruby S (2007) RESTful Web Services. O’Reilly, Springfield
Skegg D et al (2021) Future scenarios for the COVID-19 pandemic. Lancet 397(10276):777–778. https://doi.org/10.1016/S0140-6736(21)00424-4
Tullis T, Albert W (2013) Measuring the User Experience: Collecting, Analyzing, and Presenting Usability Metrics. Elsevier, Amsterdam
Vittorini P, Tarquinio A, di Orio F (2009) XML technologies for the Omaha system: a data model, a java tool and several case studies supporting home healthcare. Comput Methods Program Biomed 93(3). https://doi.org/10.1016/j.cmpb.2008.10.009
World Health Organization: WHO Coronavirus (COVID-19) Dashboard. https://covid19.who.int/
Yamin M (2018) IT applications in healthcare management: a survey. Int J Inf Technol 10(4):503–509. https://doi.org/10.1007/s41870-018-0203-3
Yao H et al (2020) Severity detection for the coronavirus disease 2019 (COVID-19) patients using a machine learning model based on the blood and urine tests. Front Cell Dev Biol 8:683. https://doi.org/10.3389/fcell.2020.00683
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Vittorini, P., Casano, N., Sinatti, G., Santini, S.J., Balsano, C. (2023). The Covid-19 Decision Support System (C19DSS) – A Mobile App. In: Fdez-Riverola, F., Rocha, M., Mohamad, M.S., Caraiman, S., Gil-González, A.B. (eds) Practical Applications of Computational Biology and Bioinformatics, 16th International Conference (PACBB 2022). PACBB 2022. Lecture Notes in Networks and Systems, vol 553. Springer, Cham. https://doi.org/10.1007/978-3-031-17024-9_3
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