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Antiviral Drugs in Dermatology and Venereology

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European Handbook of Dermatological Treatments

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Abstract

Viral infections are quite frequent in the everyday dermatovenereological practice including herpes simplex virus (HSV) infections, human papillomavirus (HPV) infections and mollusca contagiosa in the majority of cases. As with other viral diseases, treatment options are still rather limited and therefore oftentimes challenging. New therapeutic agents, especially preventive and curative vaccines are continuously being studied. For the treatment of orolabial and/or genital HSV infections we strongly encourage the use of antiviral drugs such as oral acyclovir, valacyclovir and/or famciclovir. From the 36th week of gestation on, prophylactic treatment with oral acyclovir is also strongly encouraged to prevent (also) encephalitis in newborns. Treatment of HPV infections and mollusca contagiosa remains symptomatic and based on either chemical or physical destructions. Several immunomodulatory methods exist, as well including mostly home treatments, however, proactive sequential therapy combining both ablative (office provided) and immunomodulatory (patient applied) treatment modalities has recently demonstrated to be quite efficient option in the complex management of the anogenital HPV infections.

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Authors and Affiliations

  1. Department of Dermatology and Venereology, Zagreb University School of Medicine and Zagreb University Hospital, Zagreb, Croatia

    Mihael Skerlev

  2. Department of Dermatology and Venereology, Health center Zagreb West, Zagreb, Croatia

    Ivana Čulav

  3. School of Medicine, European University Cyprus, Nicosia, Cyprus

    Andrija Stanimirović

  4. Zagreb University School of Medicine, Zagreb, Croatia

    Dominik Kutlić

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  1. Mihael Skerlev
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  2. Ivana Čulav
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  4. Dominik Kutlić
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Correspondence to Mihael Skerlev .

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Editors and Affiliations

  1. Andreas Syggros Hospital, Athens State University, Athens, Greece

    Andreas D. Katsambas

  2. Research Center CSRMR, Marconi University, Rome, Roma, Italy

    Torello M. Lotti

  3. Andreas Syggros Hospital, Athens State University, Athens, Greece

    Clio Dessinioti

  4. Dermatoloy Unit, Livorno Hospital, Livorno, Italy

    Angelo Massimiliano D'Erme

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Skerlev, M., Čulav, I., Stanimirović, A., Kutlić, D. (2023). Antiviral Drugs in Dermatology and Venereology. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D'Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Cham. https://doi.org/10.1007/978-3-031-15130-9_137

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