Skip to main content

Abstract

We define insomnia as difficulty initiating sleep, difficulty in maintaining sleep, and/or early morning awakening, resulting in a sleep deficiency despite adequate opportunity for sleep and no change in the patient’s baseline “need for sleep.” Insomnia, therefore, is a symptom, reported in a patient’s history, and there is no standard objective measure of insomnia through polysomnography (PSG) or other means. The routine use of PSG alone to evaluate insomnia is not recommended, but it is important to note that a patient’s sleep report and objective data may not always agree, and the misperception of sleep quality or quantity may be an issue (Kryger, Roth, Dement. Elsevier, 2017). This chapter also endeavors to isolate sleep disruption as the primary symptom of focus, while definitions of insomnia as a disorder often describe secondary effects and impact on daytime functioning. Given the complexity of insomnia as a symptom, we discuss these secondary effects to some degree, but mainly to clarify the primary issue of sleep disturbance.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Note about prostate cancer: Prostate cancer is a rare cause of LUTS, but still the second most diagnosed cancer in men, with an overall incidence of 131 cases per 100,000 men annually in the United States [128]. Since the advent of PSA screening, most cases are discovered while still asymptomatic and localized. However, because PSA is not specific to prostate cancer, screening with PSA can lead to a variety of harms such as overdiagnosis of a condition that might not have become clinically relevant, poor biopsy outcomes, and lingering anxiety. Thus, physicians have adopted a shared decision-making model with patients in regard to screening, noting important risk factors to include such as age, race (Black men are at the highest risk), and family history. If the patient meets any of these risk factors and is interested in screening, it should be offered.

References

  1. Hammond WA. Sleep and its derangements. London: Forgotten Books; 2015.

    Google Scholar 

  2. Kryger MH. Atlas of clinical sleep medicine: expert consult - online and print. Saunders; 2014.

    Google Scholar 

  3. National Institutes of Health Consensus Development Conference Statement. Drugs and Insomnia: the use of medications to promote sleep [Internet]. 1983. https://consensus.nih.gov/1983/1983insomniadrugs039html.htm.

  4. National Institutes of Health. National Institutes of Health State of the Science Conference statement on manifestations and management of chronic insomnia in adults, June 13–15, 2005. Sleep. 2005;28:1049–57.

    Google Scholar 

  5. Edinger JD, Kryger MH, Roth T. Insomnia. In: Kryger MH, editor. Atlas of clinical sleep medicine. 2nd ed. Philadelphia: Saunders; 2014. p. 148–58.

    Google Scholar 

  6. Kryger MH, Roth T, Dement WC. Principles and practice of sleep medicine. Philadelphia, PA: Elsevier; 2017.

    Google Scholar 

  7. Spielman AJ, Caruso LS, Glovinsky PB. A behavioral perspective on insomnia treatment. Psychiatr Clin North Am. 1987;10(4):541–53.

    CAS  PubMed  Google Scholar 

  8. Perlis M, Shaw PJ, Cano G, Espie CA. Models of insomnia. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. Elsevier; 2011. p. 850–65.

    Google Scholar 

  9. Perlis ML, Gehrman P. Types of insomnia. In: Kushida CA, editor. Encyclopedia of sleep. Academic Press: London; 2013. p. 199–202.

    Google Scholar 

  10. Riemann D, Spiegelhalder K, Feige B, Voderholzer U, Berger M, Perlis M, et al. The hyperarousal model of insomnia: a review of the concept and its evidence. Sleep Med Rev. 2010;14(1):19–31.

    PubMed  Google Scholar 

  11. Bjorness TE, Greene RW. Adenosine and sleep. Curr Neuropharmacol. 2009;7(3):238–45.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Levenson JC, Kay DB, Buysse DJ. The pathophysiology of insomnia. Chest. 2015;147(4):1179–92.

    PubMed  PubMed Central  Google Scholar 

  13. Hirshkowitz M, Whiton K, Albert SM, Alessi C, Bruni O, DonCarlos L, et al. National Sleep Foundation’s sleep time duration recommendations: methodology and results summary. Sleep Health. 2015;1(1):40–3.

    PubMed  Google Scholar 

  14. “Sleep-Wake Disorders” in American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed., text rev. Washington, DC: American Psychiatric Association; 2022. pp 407–76.

    Google Scholar 

  15. Sleep-Wakefulness [Internet]. Nih.gov. [cited 2021 Nov 23]. https://www.nimh.nih.gov/research/research-funded-by-nimh/rdoc/constructs/sleep-wakefulness.

  16. Kelly MR, Killgore WDS, Haynes PL. Understanding recent insights in sleep and posttraumatic stress disorder from a research domain criteria (RDoC) framework. Curr Sleep Med Rep. 2016;2(4):223–32.

    Google Scholar 

  17. Whitehead K, Beaumont M. Insomnia: a cultural history. Lancet. 2018;391(10138):2408–9.

    PubMed  Google Scholar 

  18. Summers-Bremner E. Insomnia: a cultural history. London: Reaktion Books; 2008.

    Google Scholar 

  19. Katzman MA, Bleau P, Blier P, Chokka P, Kjernisted K, Van Ameringen M, et al. Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry. 2014;14(Suppl 1):S1.

    PubMed  PubMed Central  Google Scholar 

  20. Kessler RC, Petukhova M, Sampson NA, Zaslavsky AM, Wittchen H-U. Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States. Int J Methods Psychiatr Res. 2012;21(3):169–84. https://doi.org/10.1002/mpr.1359.

    Article  PubMed  PubMed Central  Google Scholar 

  21. DeMartini J, Patel G, Fancher TL. Generalized anxiety disorder. Ann Intern Med. 2019;170(7):ITC49–64.

    PubMed  Google Scholar 

  22. Ferre Navarrete F, Pérez Páramo M, Fermin Ordoño J, López Gómez V. Prevalence of insomnia and associated factors in outpatients with generalized anxiety disorder treated in psychiatric clinics. Behav Sleep Med. 2017;15(6):491–501.

    CAS  PubMed  Google Scholar 

  23. Hoge EA, Ivkovic A, Fricchione GL. Generalized anxiety disorder: diagnosis and treatment. BMJ. 2012;345(v27 2):e7500.

    PubMed  Google Scholar 

  24. “Substance/Medication-Induced Sleep Disorder” in American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed., text rev. Washington, DC: American Psychiatric Association; 2022. pp 468–74.

    Google Scholar 

  25. Sachdeva A, Choudhary M, Chandra M. Alcohol withdrawal syndrome: benzodiazepines and beyond. J Clin Diagn Res. 2015;9(9):VE01–7.

    CAS  PubMed  PubMed Central  Google Scholar 

  26. Perney P, Lehert P. Insomnia in alcohol-dependent patients: prevalence, risk factors and acamprosate effect: an individual patient data meta-analysis. Alcohol Alcohol. 2018;53(5):611–8.

    CAS  PubMed  Google Scholar 

  27. Garcia AN, Salloum IM. Polysomnographic sleep disturbances in nicotine, caffeine, alcohol, cocaine, opioid, and cannabis use: a focused review: polysomnographic changes in substance use. Am J Addict. 2015;24(7):590–8.

    Google Scholar 

  28. Withdrawal Syndromes Workup [Internet]. Medscape.com. 2021. [cited 2021 Nov 23]. https://emedicine.medscape.com/article/819502-workup.

  29. Hughes JR, Oliveto AH, Liguori A, Carpenter J, Howard T. Endorsement of DSM-IV dependence criteria among caffeine users. Drug Alcohol Depend. 1998;52(2):99–107.

    CAS  PubMed  Google Scholar 

  30. Copeland J, Pokorski I. Progress toward pharmacotherapies for cannabis-use disorder: an evidence-based review. Subst Abus Rehabil. 2016;7:41–53.

    Google Scholar 

  31. Rella JG. Recreational cannabis use: pleasures and pitfalls. Cleve Clin J Med. 2015;82(11):765–72.

    PubMed  Google Scholar 

  32. Livne O, Shmulewitz D, Lev-Ran S, Hasin DS. DSM-5 cannabis withdrawal syndrome: demographic and clinical correlates in U.S. adults. Drug Alcohol Depend. 2019;195:170–7.

    PubMed  Google Scholar 

  33. Schwartz BG, Rezkalla S, Kloner RA. Cardiovascular effects of cocaine. Circulation. 2010;122(24):2558–69.

    PubMed  Google Scholar 

  34. Van Gastel A. Drug-induced insomnia and excessive sleepiness. Sleep Med Clin. 2018;13(2):147–59.

    PubMed  Google Scholar 

  35. UpToDate [Internet]. Uptodate.com. [cited 2021 Nov 23]. https://www.uptodate.com/contents/risk-factors-comorbidities-and-consequences-of-insomnia-in-adults?search=insomnia&source=search_result&selectedTitle=5~150&usage_type=default&display_rank=5.

  36. Schutte-Rodin S, Broch L, Buysse D, Dorsey C, Sateia M. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med. 2008;4(5):487–504.

    PubMed  PubMed Central  Google Scholar 

  37. Edmunds AL. Psychotic and bipolar disorders: schizophrenia. FP Essent. 2017;455:11–7.

    PubMed  Google Scholar 

  38. Kahn RS, Sommer IE, Murray RM, Meyer-Lindenberg A, Weinberger DR, Cannon TD, et al. Schizophrenia. Nat Rev Dis Primers. 2015; https://doi.org/10.1038/nrdp.2015.67.

  39. Oliveira P, Coroa M, Madeira N. Treatment options for insomnia in schizophrenia: a systematic review. Pharmacopsychiatry. 2019;52(4):165–9.

    CAS  PubMed  Google Scholar 

  40. Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RMA, Petukhova M, et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the national comorbidity survey replication. Arch Gen Psychiatry. 2007;64(5):543.

    PubMed  PubMed Central  Google Scholar 

  41. Grande I, Berk M, Birmaher B, Vieta E. Bipolar disorder. Lancet. 2016;387(10027):1561–72.

    PubMed  Google Scholar 

  42. Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018;20(2):97–170.

    PubMed  PubMed Central  Google Scholar 

  43. Serretti A, Olgiati P. Profiles of “manic” symptoms in bipolar I, bipolar II and major depressive disorders. J Affect Disord. 2005;84(2–3):159–66.

    PubMed  Google Scholar 

  44. Harvey AG, Talbot LS, Gershon A. Sleep disturbance in bipolar disorder across the lifespan. Clin Psychol (New York). 2009;16(2):256–77.

    PubMed  Google Scholar 

  45. UpToDate [Internet]. Uptodate.com. [cited 2021 Nov 23]. https://www.uptodate.com/contents/sleep-wake-disorders-in-patients-with-traumatic-brain-injury?search=insomnia&topicRef=97867&source=see_link.

  46. Haider MN, Leddy JJ, Du W, Macfarlane AJ, Viera KB, Willer BS. Practical management: brief physical examination for sport-related concussion in the outpatient setting. Clin J Sport Med. 2018;30(5):513–7.

    Google Scholar 

  47. Overview | Head injury: assessment and early management | Guidance | NICE. [cited 2021 Nov 23]. https://www.nice.org.uk/guidance/cg176.

  48. McCrory P, Meeuwisse W, Dvorak J, Aubry M, Bailes J, Broglio S, et al. Consensus statement on concussion in sport—the 5th International Conference on Concussion in Sport Held in Berlin, October 2016. Br J Sports Med. 2017; https://doi.org/10.1136/bjsports-2017-097699.

  49. VA/DoD clinical practice guidelines [Internet]. Healthquality.va.gov. [cited 2021 Nov 23]. https://www.healthquality.va.gov/guidelines/rehab/mtbi/.

  50. Warner CH, Warner CM, Appenzeller GN, Hoge CW. Identifying and managing posttraumatic stress disorder. Am Fam Physician. 2013;88(12):827–34.

    PubMed  Google Scholar 

  51. Hines LA, Sundin J, Rona RJ, Wessely S, Fear NT. Posttraumatic stress disorder post Iraq and Afghanistan: prevalence among military subgroups. Can J Psychiatr. 2014;59(9):468–79.

    Google Scholar 

  52. Wallace DM, Shafazand S, Ramos AR, Carvalho DZ, Gardener H, Lorenzo D, et al. Insomnia characteristics and clinical correlates in Operation Enduring Freedom/Operation Iraqi Freedom veterans with post-traumatic stress disorder and mild traumatic brain injury: an exploratory study. Sleep Med. 2011;12(9):850–9.

    CAS  PubMed  Google Scholar 

  53. Kobayashi I, Boarts JM, Delahanty DL. Polysomnographically measured sleep abnormalities in PTSD: a meta-analytic review. Psychophysiology. 2007;44(4):660–9.

    PubMed  Google Scholar 

  54. Barbato G, Barker C, Bender C, Giesen HA, Wehr TA. Extended sleep in humans in 14 hour nights (LD 10:14): relationship between REM density and spontaneous awakening. Electroencephalogr Clin Neurophysiol. 1994;90(4):291–7.

    CAS  PubMed  Google Scholar 

  55. Mellman TA, Kumar A, Kulick-Bell R, Kumar M, Nolan B. Nocturnal/daytime urine noradrenergic measures and sleep in combat-related PTSD. Biol Psychiatry. 1995;38(3):174–9.

    CAS  PubMed  Google Scholar 

  56. Woodward SH, Murburg MM, Bliwise DL. PTSD-related hyperarousal assessed during sleep. Physiol Behav. 2000;70(1–2):197–203.

    CAS  PubMed  Google Scholar 

  57. Kanny D, Brewer RD, Mesnick JB, Paulozzi LJ, Naimi TS, Lu H. Vital signs: alcohol poisoning deaths - United States, 2010–2012. MMWR Morb Mortal Wkly Rep. 2015;63(53):1238–42.

    PubMed  PubMed Central  Google Scholar 

  58. Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, et al. Epidemiology of DSM-5 alcohol use disorder: results from the National Epidemiologic Survey on alcohol and related conditions III. JAMA Psychiat. 2015;72(8):757–66.

    Google Scholar 

  59. Thakkar MM, Sharma R, Sahota P. Alcohol disrupts sleep homeostasis. Alcohol. 2015;49(4):299–310.

    CAS  PubMed  Google Scholar 

  60. Conroy DA, Arnedt JT. Sleep and substance use disorders: an update. Curr Psychiatry Rep. 2014;16(10):487.

    PubMed  Google Scholar 

  61. Karg RS, Bose J, Batts KR, et al. Past year mental disorders among adults in the United States: results from the 2008–2012 Mental Health Surveillance Study. CBHSQ Data Review, vol. 232. Rockville, MD: Substance Abuse and Mental Health Services Administration (US); 2014. p. 10.

    Google Scholar 

  62. Kessler RC, Ormel J, Petukhova M, McLaughlin KA, Green JG, Russo LJ, et al. Development of lifetime comorbidity in the World Health Organization world mental health surveys. Arch Gen Psychiatry. 2011;68(1):90–100.

    PubMed  PubMed Central  Google Scholar 

  63. Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ, et al. A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders. JAMA Psychiat. 2014;71(5):573–81.

    Google Scholar 

  64. Murphy MJ, Peterson MJ. Sleep disturbances in depression. Sleep Med Clin. 2015;10(1):17–23.

    PubMed  Google Scholar 

  65. Peterson MJ, Benca RM. Sleep in mood disorders. Psychiatr Clin North Am. 2006;29(4):1009–32. abstract ix

    PubMed  Google Scholar 

  66. Bjorøy I, Jørgensen VA, Pallesen S, Bjorvatn B. The prevalence of insomnia subtypes in relation to demographic characteristics, anxiety, depression, alcohol consumption and use of hypnotics. Front Psychol. 2020;11:527.

    PubMed  PubMed Central  Google Scholar 

  67. Coleman MY, McGlashan EM, Vidafar P, Phillips AJK, Cain SW. Advanced melatonin onset relative to sleep in women with unmedicated major depressive disorder. Chronobiol Int. 2019;36(10):1373–83.

    CAS  PubMed  Google Scholar 

  68. Emens J, Lewy A, Kinzie JM, Arntz D, Rough J. Circadian misalignment in major depressive disorder. Psychiatry Res. 2009;168(3):259–61.

    PubMed  Google Scholar 

  69. McGlashan EM, Nandam LS, Vidafar P, Mansfield DR, Rajaratnam SMW, Cain SW. The SSRI citalopram increases the sensitivity of the human circadian system to light in an acute dose. Psychopharmacology. 2018;235(11):3201–9.

    CAS  PubMed  Google Scholar 

  70. Robillard R, Carpenter JS, Rogers NL, Fares S, Grierson AB, Hermens DF, et al. Circadian rhythms and psychiatric profiles in young adults with unipolar depressive disorders. Transl Psychiatry. 2018;8(1):213.

    PubMed  PubMed Central  Google Scholar 

  71. American Psychiatric Association. Depressive disorders. In: American Psychiatric Association, editor. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington, VA: American Psychiatric Association; 2013. p. 155–88.

    Google Scholar 

  72. Beck AT. The evolution of the cognitive model of depression and its neurobiological correlates. Am J Psychiatry. 2008;165(8):969–77.

    PubMed  Google Scholar 

  73. Garcia-Borreguero D, Cano-Pumarega I. New concepts in the management of restless legs syndrome. BMJ. 2017;356:j104.

    PubMed  Google Scholar 

  74. Innes KE, Selfe TK, Agarwal P. Prevalence of restless legs syndrome in North American and Western European populations: a systematic review. Sleep Med. 2011;12(7):623–34.

    PubMed  PubMed Central  Google Scholar 

  75. Cho S-J, Hong JP, Hahm B-J, Jeon HJ, Chang SM, Cho MJ, et al. Restless legs syndrome in a community sample of Korean adults: prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders. Sleep. 2009;32(8):1069–76.

    PubMed  PubMed Central  Google Scholar 

  76. Hening W, Walters AS, Allen RP, Montplaisir J, Myers A, Ferini-Strambi L. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study. Sleep Med. 2004;5(3):237–46.

    PubMed  Google Scholar 

  77. Trenkwalder C, Högl B, Winkelmann J. Recent advances in the diagnosis, genetics and treatment of restless legs syndrome. J Neurol. 2009;256(4):539–53.

    CAS  PubMed  Google Scholar 

  78. Winkelmann J, Prager M, Lieb R, Pfister H, Spiegel B, Wittchen H-U, et al. “Anxietas tibiarum”. Depression and anxiety disorders in patients with restless legs syndrome: depression and anxiety disorders in patients with restless legs syndrome. J Neurol. 2005;252(1):67–71.

    CAS  PubMed  Google Scholar 

  79. Durmer JS, Quraishi GH. Restless legs syndrome, periodic leg movements, and periodic limb movement disorder in children. Pediatr Clin N Am. 2011;58(3):591–620.

    Google Scholar 

  80. Trenkwalder C, Paulus W. Restless legs syndrome: pathophysiology, clinical presentation and management. Nat Rev Neurol. 2010;6(6):337–46.

    PubMed  Google Scholar 

  81. Garcia-Borreguero D, Stillman P, Benes H, Buschmann H, Chaudhuri KR, Gonzalez Rodríguez VM, et al. Algorithms for the diagnosis and treatment of restless legs syndrome in primary care. BMC Neurol. 2011;11(1):28.

    PubMed  PubMed Central  Google Scholar 

  82. Benes H, Kohnen R. Validation of an algorithm for the diagnosis of restless legs syndrome: the Restless Legs Syndrome-Diagnostic Index (RLS-DI). Sleep Med. 2009;10(5):515–23.

    PubMed  Google Scholar 

  83. Trotti LM, Rye DB. Restless legs syndrome. Handb Clin Neurol. 2011;100:661–73.

    PubMed  Google Scholar 

  84. Stiasny-Kolster K, Kohnen R, Möller JC, Trenkwalder C, Oertel WH. Validation of the “L-DOPA test” for diagnosis of restless legs syndrome. Mov Disord. 2006;21(9):1333–9.

    PubMed  Google Scholar 

  85. Sivertsen B, Pallesen S, Stormark KM, Bøe T, Lundervold AJ, Hysing M. Delayed sleep phase syndrome in adolescents: prevalence and correlates in a large population based study. BMC Public Health. 2013;13(1):1163.

    PubMed  PubMed Central  Google Scholar 

  86. Yazaki M, Shirakawa S, Okawa M, Takahashi K. Demography of sleep disturbances associated with circadian rhythm disorders in Japan. Psychiatry Clin Neurosci. 1999;53(2):267–8.

    CAS  PubMed  Google Scholar 

  87. Magee M, Marbas EM, Wright KP Jr, Rajaratnam SMW, Broussard JL. Diagnosis, cause, and treatment approaches for delayed sleep-wake phase disorder. Sleep Med Clin. 2016;11(3):389–401.

    PubMed  Google Scholar 

  88. Pavlova M. Circadian rhythm sleep-wake disorders. Continuum (Minneap Minn). 2017;23(4):1051–63.

    PubMed  Google Scholar 

  89. American Academy of Sleep Medicine. International classification of sleep disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.

    Google Scholar 

  90. Morgenthaler TI, Lee-Chiong T, Alessi C, Friedman L, Aurora RN, Boehlecke B, et al. Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. Sleep. 2007;30(11):1445–59.

    PubMed  PubMed Central  Google Scholar 

  91. Marino M, Li Y, Rueschman MN, Winkelman JW, Ellenbogen JM, Solet JM, et al. Measuring sleep: accuracy, sensitivity, and specificity of wrist actigraphy compared to polysomnography. Sleep. 2013;36(11):1747–55.

    PubMed  PubMed Central  Google Scholar 

  92. Morgenthaler T, Alessi C, Friedman L, Owens J, Kapur V, Boehlecke B, et al. Practice parameters for the use of actigraphy in the assessment of sleep and sleep disorders: an update for 2007. Sleep. 2007;30(4):519–29.

    PubMed  Google Scholar 

  93. Smith MT, McCrae CS, Cheung J, Martin JL, Harrod CG, Heald JL, et al. Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med. 2018;14(07):1209–30.

    PubMed  PubMed Central  Google Scholar 

  94. Sack RL, Auckley D, Auger RR, Carskadon MA, Wright KP Jr, Vitiello MV, et al. Circadian rhythm sleep disorders: Part II, Advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine review. Sleep. 2007;30(11):1484–501.

    PubMed  PubMed Central  Google Scholar 

  95. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of COPD. GOLD 2020. 2020. Fontana, WI.

    Google Scholar 

  96. Halbert RJ, Isonaka S, George D, Iqbal A. Interpreting COPD prevalence estimates: what is the true burden of disease? Chest. 2003;123(5):1684–92.

    CAS  PubMed  Google Scholar 

  97. Centers for Disease Control and Prevention (CDC). Chronic obstructive pulmonary disease among adults—United States, 2011. MMWR Morb Mortal Wkly Rep. 2012;61(46):938–43.

    Google Scholar 

  98. Vukoja M, Kopitovic I, Milicic D, Maksimovic O, Pavlovic-Popovic Z, Ilic M. Sleep quality and daytime sleepiness in patients with COPD and asthma. Clin Respir J. 2018;12(2):398–403.

    PubMed  Google Scholar 

  99. Stephens MB, Yew KS. Diagnosis of chronic obstructive pulmonary disease. Am Fam Physician. 2008;78(1):87–92.

    PubMed  Google Scholar 

  100. de Mattos WLLD, Signori LGH, Borges FK, Bergamin JA, Machado V. Tital: Accuracy of clinical examination findings in the diagnosis of COPD. J Bras Pneumol. 2009;35(5):404–8.

    Google Scholar 

  101. Demirci H, Eniste K, Basaran EO, Ocakoglu G, Yilmaz Z, Tuna S. A multicenter family practitioners’ research on chronic obstructive pulmonary disease screening using the COPD assessment test. Prim Health Care Res Dev. 2017;18(6):603–7.

    PubMed  Google Scholar 

  102. Ban WH, Joo H, Lim JU, Kang HH, Moon HS, Lee SH. The relationship between sleep disturbance and health status in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:2049–55.

    PubMed  PubMed Central  Google Scholar 

  103. Young T, Palta M, Dempsey J, Peppard PE, Nieto FJ, Hla KM. Burden of sleep apnea: rationale, design, and major findings of the Wisconsin Sleep Cohort study. WMJ. 2009;108(5):246–9.

    PubMed  PubMed Central  Google Scholar 

  104. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006–14.

    PubMed  PubMed Central  Google Scholar 

  105. Johns M. About the ESS [Internet]. Epworth Sleepiness Scale. [cited 2021 Dec 19]. https://epworthsleepinessscale.com/about-the-ess/.

  106. Myers KA, Mrkobrada M, Simel DL. Does this patient have obstructive sleep apnea?: the rational clinical examination systematic review. JAMA. 2013;310(7):731–41.

    CAS  PubMed  Google Scholar 

  107. Russell MB, Kristiansen HA, Kværner KJ. Headache in sleep apnea syndrome: epidemiology and pathophysiology. Cephalalgia. 2014;34(10):752–5.

    PubMed  Google Scholar 

  108. Lin C-H, Perger E, Lyons OD. Obstructive sleep apnea and chronic kidney disease. Curr Opin Pulm Med. 2018;24(6):549–54. https://doi.org/10.1097/MCP.0000000000000525.

    Article  PubMed  Google Scholar 

  109. Reutrakul S, Mokhlesi B. Obstructive sleep apnea and diabetes: a state of the art review. Chest. 2017;152(5):1070–86.

    PubMed  PubMed Central  Google Scholar 

  110. Flemons WW, Whitelaw WA, Brant R, Remmers JE. Likelihood ratios for a sleep apnea clinical prediction rule. Am J Respir Crit Care Med. 1994;150(5 Pt 1):1279–85.

    CAS  PubMed  Google Scholar 

  111. Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2017;13(03):479–504.

    PubMed  PubMed Central  Google Scholar 

  112. Friedman M, Hamilton C, Samuelson CG, Lundgren ME, Pott T. Diagnostic value of the Friedman tongue position and Mallampati classification for obstructive sleep apnea: a meta-analysis. Otolaryngol Head Neck Surg. 2013;148(4):540–7.

    PubMed  Google Scholar 

  113. Chiu H-Y, Chen P-Y, Chuang L-P, Chen N-H, Tu Y-K, Hsieh Y-J, et al. Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea: a bivariate meta-analysis. Sleep Med Rev. 2017;36:57–70.

    PubMed  Google Scholar 

  114. Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S, et al. STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology. 2008;108(5):812–21.

    PubMed  Google Scholar 

  115. Araujo AB, Yaggi HK, Yang M, McVary KT, Fang SC, Bliwise DL. Sleep related problems and urological symptoms: testing the hypothesis of bidirectionality in a longitudinal, population based study. J Urol. 2014;191(1):100–6.

    PubMed  Google Scholar 

  116. Patel SR, Hu FB. Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring). 2008;16(3):643–53.

    PubMed  Google Scholar 

  117. Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet. 1999;354(9188):1435–9.

    CAS  PubMed  Google Scholar 

  118. Yaggi HK, Araujo AB, McKinlay JB. Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care. 2006;29(3):657–61.

    PubMed  Google Scholar 

  119. Simpson N, Dinges DF. Sleep and inflammation. Nutr Rev. 2007;65(12 Pt 2):S244–52.

    PubMed  Google Scholar 

  120. Fitzgerald MP, Mulligan M, Parthasarathy S. Nocturic frequency is related to severity of obstructive sleep apnea, improves with continuous positive airways treatment. Am J Obstet Gynecol. 2006;194(5):1399–403.

    PubMed  Google Scholar 

  121. Pressman MR, Figueroa WG, Kendrick-Mohamed J, Greenspon LW, Peterson DD. Nocturia. A rarely recognized symptom of sleep apnea and other occult sleep disorders. Arch Intern Med. 1996;156(5):545–50.

    CAS  PubMed  Google Scholar 

  122. Wei JT, Calhoun E, Jacobsen SJ. Urologic diseases in America project: benign prostatic hyperplasia. J Urol. 2005;173(4):1256–61.

    PubMed  Google Scholar 

  123. Chute CG, Panser LA, Girman CJ, Oesterling JE, Guess HA, Jacobsen SJ, et al. The prevalence of prostatism: a population-based survey of urinary symptoms. J Urol. 1993;150(1):85–9.

    CAS  PubMed  Google Scholar 

  124. Roehrborn CG. Accurate determination of prostate size via digital rectal examination and transrectal ultrasound. Urology. 1998;51(4):19–22.

    PubMed  Google Scholar 

  125. Pinsky PF, Kramer BS, Crawford ED, Grubb RL, Urban DA, Andriole GL, et al. Prostate volume and prostate-specific antigen levels in men enrolled in a large screening trial. Urology. 2006;68(2):352–6.

    PubMed  Google Scholar 

  126. McVary KT, Roehrborn CG, Avins AL, Barry MJ, Bruskewitz RC, Donnell RF, et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol. 2011;185(5):1793–803.

    PubMed  Google Scholar 

  127. Khadra MH, Pickard RS, Charlton M, Powell PH, Neal DE. A prospective analysis of 1,930 patients with hematuria to evaluate current diagnostic practice. J Urol. 2000;163(2):524–7.

    CAS  PubMed  Google Scholar 

  128. Butler SS, Muralidhar V, Zhao SG, Sanford NN, Franco I, Fullerton ZH, et al. Prostate cancer incidence across stage, NCCN risk groups, and age before and after USPSTF Grade D recommendations against prostate-specific antigen screening in 2012. Cancer. 2020;126(4):717–24.

    CAS  PubMed  Google Scholar 

  129. Foster HE, Barry MJ, Dahm P, Gandhi MC, Kaplan SA, Kohler TS, et al. Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA guideline. J Urol. 2018;200(3):612–9.

    PubMed  Google Scholar 

  130. Liao C-H, Chung S-D, Kuo H-C. Diagnostic value of International Prostate Symptom Score voiding-to-storage subscore ratio in male lower urinary tract symptoms: diagnostic value of IPSS subscores. Int J Clin Pract. 2011;65(5):552–8. https://doi.org/10.1111/j.1742-1241.2011.02638.x.

    Article  PubMed  Google Scholar 

  131. Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction: terminology for female pelvic floor dysfunction. Neurourol Urodyn. 2010;29(1):4–20.

    PubMed  Google Scholar 

  132. Hartmann KE, McPheeters ML, Biller DH, Ward RM, McKoy JN, Jerome RN, et al. Treatment of overactive bladder in women. Evid Rep Technol Assess (Full Rep). 2009;(187):1–120, v.

    Google Scholar 

  133. Dmochowski RR, Gomelsky A. Overactive bladder in males. Ther Adv Urol. 2009;1(4):209–21.

    PubMed  PubMed Central  Google Scholar 

  134. Shamliyan T, Wyman J, Bliss DZ, Kane RL, Wilt TJ. Prevention of urinary and fecal incontinence in adults. Evid Rep Technol Assess (Full Rep). 2007;(161):1–379.

    Google Scholar 

  135. Fitzgerald MP, Thom DH, Wassel-Fyr C, Subak L, Brubaker L, Van Den Eeden SK, et al. Childhood urinary symptoms predict adult overactive bladder symptoms. J Urol. 2006;175(3 Pt 1):989–93.

    PubMed  PubMed Central  Google Scholar 

  136. Nygaard I. Clinical practice. Idiopathic urgency urinary incontinence. N Engl J Med. 2010;363(12):1156–62.

    CAS  PubMed  Google Scholar 

  137. Suskind AM, Dunn RL, Morgan DM, DeLancey JOL, McGuire EJ, Wei JT. The Michigan Incontinence Symptom Index (M-ISI): a clinical measure for type, severity, and bother related to urinary incontinence: Incontinence Symptom Index. Neurourol Urodyn. 2014;33(7):1128–34.

    PubMed  Google Scholar 

  138. Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R, Global Consensus Group. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101(8):1900–20. quiz 1943

    PubMed  Google Scholar 

  139. Richter JE. Typical and atypical presentations of gastroesophageal reflux disease. The role of esophageal testing in diagnosis and management. Gastroenterol Clin N Am. 1996;25(1):75–102.

    CAS  Google Scholar 

  140. Giannini EG, Zentilin P, Dulbecco P, Vigneri S, Scarlata P, Savarino V. Management strategy for patients with gastroesophageal reflux disease: a comparison between empirical treatment with esomeprazole and endoscopy-oriented treatment. Am J Gastroenterol. 2008;103(2):267–75.

    CAS  PubMed  Google Scholar 

  141. Dent J, Vakil N, Jones R, Bytzer P, Schoning U, Halling K, et al. Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study. Gut. 2010;59(6):714–21.

    PubMed  Google Scholar 

  142. Zagari RM, Fuccio L, Wallander M-A, Johansson S, Fiocca R, Casanova S, et al. Gastro-oesophageal reflux symptoms, oesophagitis and Barrett’s oesophagus in the general population: the Loiano-Monghidoro study. Gut. 2008;57(10):1354–9.

    CAS  PubMed  Google Scholar 

  143. Gyawali CP, Kahrilas PJ, Savarino E, Zerbib F, Mion F, Smout AJPM, et al. Modern diagnosis of GERD: the Lyon consensus. Gut. 2018;67(7):1351–62.

    PubMed  Google Scholar 

  144. Moayyedi P, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. ACG and CAG clinical guideline: management of dyspepsia. Am J Gastroenterol. 2017;112(7):988–1013.

    CAS  PubMed  Google Scholar 

  145. ASGE Standards of Practice Committee, Muthusamy VR, Lightdale JR, Acosta RD, Chandrasekhara V, Chathadi KV, et al. The role of endoscopy in the management of GERD. Gastrointest Endosc. 2015;81(6):1305–10.

    Google Scholar 

  146. Jones R, Junghard O, Dent J, Vakil N, Halling K, Wernersson B, et al. Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther. 2009;30(10):1030–8.

    CAS  PubMed  Google Scholar 

  147. Numans ME, Lau J, de Wit NJ, Bonis PA. Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics. Ann Intern Med. 2004;140(7):518.

    CAS  PubMed  Google Scholar 

  148. Kellerman R, Kintanar T. Gastroesophageal reflux disease. Prim Care. 2017;44(4):561–73.

    PubMed  Google Scholar 

  149. Harnik IG. Gastroesophageal reflux disease. Ann Intern Med. 2015;163(1):ITC1–16.

    PubMed  Google Scholar 

  150. Xu X, Chen Q, Liang S, Lv H, Qiu Z. Comparison of gastroesophageal reflux disease questionnaire and multichannel intraluminal impedance pH monitoring in identifying patients with chronic cough responsive to antireflux therapy. Chest. 2014;145(6):1264–70. https://doi.org/10.1378/chest.13-1634.

    Article  PubMed  Google Scholar 

  151. Treede R-D, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, et al. Chronic pain as a symptom or a disease: the IASP classification of chronic pain for the International Classification of Diseases (ICD-11). Pain. 2019;160(1):19–27.

    PubMed  Google Scholar 

  152. Currow DC, Agar M, Plummer JL, Blyth FM, Abernethy AP. Chronic pain in South Australia - population levels that interfere extremely with activities of daily living. Aust N Z J Public Health. 2010;34(3):232–9.

    PubMed  Google Scholar 

  153. Goldberg DS, McGee SJ. Pain as a global public health priority. BMC Public Health. 2011;11(1):770.

    PubMed  PubMed Central  Google Scholar 

  154. Henderson JV, Harrison CM, Britt HC, Bayram CF, Miller GC. Prevalence, causes, severity, impact, and management of chronic pain in Australian general practice patients. Pain Med. 2013;14(9):1346–61.

    PubMed  Google Scholar 

  155. Patel KV, Guralnik JM, Dansie EJ, Turk DC. Prevalence and impact of pain among older adults in the United States: findings from the 2011 National Health and Aging Trends Study. Pain. 2013;154(12):2649–57.

    PubMed  Google Scholar 

  156. Pitcher MH, Von Korff M, Bushnell MC, Porter L. Prevalence and profile of high-impact chronic pain in the United States. J Pain. 2019;20(2):146–60.

    PubMed  Google Scholar 

  157. International Association for the Study of Pain. Chronic pain management: measurement-based step care solutions. Pain Clin Updates. 2012;10:1–8.

    Google Scholar 

  158. Mathias JL, Cant ML, Burke ALJ. Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis. Sleep Med. 2018;52:198–210.

    CAS  PubMed  Google Scholar 

  159. Reid MC, Eccleston C, Pillemer K. Management of chronic pain in older adults. BMJ. 2015;350(feb13 2):h532.

    PubMed  PubMed Central  Google Scholar 

  160. Erdemoglu AK, Koc R. Brief Pain Inventory score identifying and discriminating neuropathic and nociceptive pain. Acta Neurol Scand. 2013;128(5):351–8.

    CAS  PubMed  Google Scholar 

  161. Paine S-J, Fink J, Gander PH, Warman GR. Identifying advanced and delayed sleep phase disorders in the general population: a national survey of New Zealand adults. Chronobiol Int. 2014;31(5):627–36.

    PubMed  Google Scholar 

  162. Curtis BJ, Ashbrook LH, Young T, Finn LA, Fu Y-H, Ptáček LJ, et al. Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep-wake phase disorder in a sleep clinic population. Sleep. 2019; https://doi.org/10.1093/sleep/zsz148.

  163. Rahman SA, Kayumov L, Tchmoutina EA, Shapiro CM. Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndrome. Sleep Med. 2009;10(5):549–55.

    PubMed  Google Scholar 

  164. Dijk D-J, Duffy JF. Novel approaches for assessing circadian rhythmicity in humans: a review. J Biol Rhythm. 2020;35(5):421–38.

    Google Scholar 

  165. Martin J, Shochat T, Ancoli-Israel S. Assessment and treatment of sleep disturbances in older adults. Clin Psychol Rev. 2000;20(6):783–805.

    CAS  PubMed  Google Scholar 

  166. Neubauer DN. Sleep problems in the elderly. Am Fam Physician. 1999;59(9):2551–8, 2559–60.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lan-Anh T. Tran .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Tran, LA.T., Gray, K.J., Shukla, S.D., Goldstein, M.J., Capaldi, V.F. (2023). Insomnia. In: Meyer, E.G., Cozza, K.L., Bourgeois, J.A. (eds) The Medical Evaluation of Psychiatric Symptoms. Springer, Cham. https://doi.org/10.1007/978-3-031-14372-4_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-14372-4_4

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-14371-7

  • Online ISBN: 978-3-031-14372-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics