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Potential of Herbal Drugs for Treatment of Tuberculosis

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Tubercular Drug Delivery Systems

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Abstract

Worldwide, TB is estimated as the 13th leading cause of death and the second leading infectious disease after COVID-19. In 2020, an estimated 10 million people fell ill with tuberculosis (TB) worldwide. The current first-line drug treatment against tuberculosis has various limitations, of poor efficiency in complicated TB cases, side effects and lengthy drug treatment regime. Antibiotics like rifampicin, ethambutol, isoniazid, and pyrazinamide are currently used to treat tuberculosis, but multiple drug resistance is a major problem associated with it. Many traditional practices and medicinal plants have been in use as adjuvant for the treatment and management of TB.

This chapter gives an overview of medicinal plants and some of the bioactives found to be reported with a prominent effect against TB. The mechanism behind the interaction of anti-TB drugs and herbal constituents and their novel delivery approaches are also discussed.

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  1. Institute of Pharmacy, Nirma University, Ahmedabad, India

    Vishwa Patel, Dipal Gandhi, Hetanshi Patel & Niyati Acharya

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Patel, V., Gandhi, D., Patel, H., Acharya, N. (2023). Potential of Herbal Drugs for Treatment of Tuberculosis. In: Shegokar, R., Pathak, Y. (eds) Tubercular Drug Delivery Systems. Springer, Cham. https://doi.org/10.1007/978-3-031-14100-3_15

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