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Treatment Options for Acoustic Neuroma, Including Stereotactic Radiosurgery

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Surgery of the Cerebellopontine Angle

Abstract

Vestibular schwannoma (VS) represents a challenging intracranial tumor to treat. Almost a century ago, the most prominent neurosurgeons in Europe reported operative mortality rates greater than 70% [1–3]. Harvey Cushing, in the US, advocated for a wide bilateral posterior fossa decompression and intracapsular internal decompression of the tumor to achieve a safe subtotal resection (STR) and reduced the operative mortality to ~20% [4, 5]. Walter Dandy, on the other hand, described a unilateral craniectomy and complete tumor removal with the necessary sacrifice of cranial nerves VII and VIII but obviating the risk of tumor regrowth and need for additional treatment [6–9]. Over the next several decades, the integration of the operating microscope, improvement in neuroanesthetic techniques, and development of intraoperative electromyographic (EMG) monitoring have markedly improved the outcome from microsurgical resection of VS.

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References

  1. Ballance SCA. Some points in the surgery of the brain and its membranes. London: Macmillan; 1908.

    Google Scholar 

  2. Koerbel A, Gharabaghi A, Safavi-Abbasi S, Tatagiba M, Samii M. Evolution of vestibular schwannoma surgery: the long journey to current success. Neurosurg Focus. 2005;18:e10.

    Article  Google Scholar 

  3. Krause F. Discussion of von Eiselsberg’s paper. Tr Int Cong Med Lond VII. 1913;214.

    Google Scholar 

  4. Cushing H. Tumors of the nervus acusticus and the syndrome of the cerebellopontile angle. Philadelphia: W.B. Saunders; 1917.

    Google Scholar 

  5. Cushing H. Further concerning the acoustic neuromas. Laryngoscope. 1921;31:209–28.

    Article  Google Scholar 

  6. Dandy WE. An operation for the total extirpation of tumors in the cerebello-pontine angle. A preliminary report. Bull Johns Hopkins Hosp. 1922;33:344–5.

    Google Scholar 

  7. Dandy WE, Others. An operation for the total removal of cerebellopontine (acoustic) tumors. Surg Gynecol Obstet. 1925;41:129–48.

    Google Scholar 

  8. Dandy WE. Removal of cerebellopontile (acoustic) tumors through a unilateral approach. Arch Surg. 1934;29:337–44.

    Article  Google Scholar 

  9. Dandy WE. Results of removal of acoustic tumors by the unilateral approach. Arch Surg. 1941;42:1026–33.

    Article  Google Scholar 

  10. Leksell L. A note on the treatment of acoustic tumours. Acta Chir Scand. 1971;137:763–5.

    CAS  Google Scholar 

  11. Flickinger JC, Lunsford LD, Linskey ME, Duma CM, Kondziolka D. Gamma knife radiosurgery for acoustic tumors: multivariate analysis of four year results. Radiother Oncol. 1993;27:91–8.

    Article  CAS  Google Scholar 

  12. Smouha EE, Yoo M, Mohr K, Davis RP. Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm. Laryngoscope. 2005;115:450–4.

    Article  Google Scholar 

  13. Yoshimoto Y. Systematic review of the natural history of vestibular schwannoma. J Neurosurg. 2005;103:59–63.

    Article  Google Scholar 

  14. Hajioff D, Raut VV, Walsh RM, et al. Conservative management of vestibular schwannomas: third review of a 10-year prospective study. Clin Otolaryngol. 2008;33:255–9.

    Article  CAS  Google Scholar 

  15. Malhotra PS, Sharma P, Fishman MA, et al. Clinical, radiographic, and audiometric predictors in conservative management of vestibular schwannoma. Otol Neurotol. 2009;30:507–14.

    Article  Google Scholar 

  16. Hoistad DL, Melnik G, Mamikoglu B, Battista R, O’Connor CA, Wiet RJ. Update on conservative management of acoustic neuroma. Otol Neurotol. 2001;22:682–5.

    Article  CAS  Google Scholar 

  17. Shin YJ, Fraysse B, Cognard C, et al. Effectiveness of conservative management of acoustic neuromas. Am J Otol. 2000;21:857–62.

    CAS  Google Scholar 

  18. Stangerup S-E, Caye-Thomasen P. Epidemiology and natural history of vestibular schwannomas. Otolaryngol Clin N Am. 2012;45:257–68.

    Article  Google Scholar 

  19. Pullicino R, Radon M, Biswas S, Bhojak M, Das K. A review of the current evidence on gadolinium deposition in the brain. Clin Neuroradiol. 2018;28:159–69. https://doi.org/10.1007/s00062-018-0678-0.

    Article  Google Scholar 

  20. Olson JJ, Kalkanis SN, Ryken TC. Congress of neurological surgeons systematic review and evidence-based guidelines on the treatment of adults with vestibular schwannomas: executive summary. Neurosurgery. 2018;82:129–34.

    Article  Google Scholar 

  21. Van Gompel JJ, Patel J, Danner C, et al. Acoustic neuroma observation associated with an increase in symptomatic tinnitus: results of the 2007–2008 Acoustic Neuroma Association survey. Collections. 2013;118:864–8.

    Google Scholar 

  22. Stangerup S-E, Thomsen J, Tos M, Cayé-Thomasen P. Long-term hearing preservation in vestibular schwannoma. Otol Neurotol. 2010;31:271–5.

    Article  Google Scholar 

  23. Balkany TA, Gates GA, Goldenberg RA, et al. Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). Otolaryngol Head Neck Surg. 1995;113:179–80.

    Article  Google Scholar 

  24. Kirchmann M, Karnov K, Hansen S, Dethloff T, Stangerup S-E, Caye-Thomasen P. Ten-year follow-up on tumor growth and hearing in patients observed with an intracanalicular vestibular schwannoma. Neurosurgery. 2017;80:49–56.

    Article  Google Scholar 

  25. Flint D, Fagan P, Panarese A. Conservative management of sporadic unilateral acoustic neuromas. J Laryngol Otol. 2005;119:424–8.

    Article  Google Scholar 

  26. Telian SA. Management of the small acoustic neuroma: a decision analysis. Am J Otol. 1994;15:358–65.

    CAS  Google Scholar 

  27. Murphy ES, Suh JH. Radiotherapy for vestibular schwannomas: a critical review. Int J Radiat Oncol Biol Phys. 2011;79:985–97.

    Article  Google Scholar 

  28. Link MJ, Driscoll CLW, Foote RL, Pollock BE. Radiation therapy and radiosurgery for vestibular schwannomas: indications, techniques, and results. Otolaryngol Clin N Am. 2012;45:353–66.

    Article  Google Scholar 

  29. Kondziolka D, Lunsford LD, McLaughlin MR, Flickinger JC. Long-term outcomes after radiosurgery for acoustic neuromas. N Engl J Med. 1998;339:1426–33.

    Article  CAS  Google Scholar 

  30. Chopra R, Kondziolka D, Niranjan A, Lunsford LD, Flickinger JC. Long-term follow-up of acoustic schwannoma radiosurgery with marginal tumor doses of 12 to 13 Gy. Int J Radiat Oncol Biol Phys. 2007;68:845–51.

    Article  Google Scholar 

  31. Hasegawa T, Fujitani S, Katsumata S, Kida Y, Yoshimoto M, Koike J. Stereotactic radiosurgery for vestibular schwannomas: analysis of 317 patients followed more than 5 years. Neurosurgery. 2005;57:257–65.

    Article  Google Scholar 

  32. Pollock BE, Lunsford LD, Kondziolka D, et al. Outcome analysis of acoustic neuroma management: a comparison of microsurgery and stereotactic radiosurgery. Neurosurgery. 1995;36:215–24.

    Article  CAS  Google Scholar 

  33. Friedman RA, Kesser B, Brackmann DE, Fisher LM, Slattery WH, Hitselberger WE. Long-term hearing preservation after middle fossa removal of vestibular schwannoma. Otolaryngol Head Neck Surg. 2003;129:660–5.

    Article  Google Scholar 

  34. Régis J, Pellet W, Delsanti C, et al. Functional outcome after gamma knife surgery or microsurgery for vestibular schwannomas. J Neurosurg. 2013;119:1091–100.

    Google Scholar 

  35. Yang I, Sughrue ME, Han SJ, et al. A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannoma. J Neurosurg. 2010;112:851–9.

    Article  Google Scholar 

  36. Kano H, Kondziolka D, Khan A, Flickinger JC, Lunsford LD. Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma. J Neurosurg. 2009;111:863–73.

    Article  Google Scholar 

  37. Hasegawa T, Kida Y, Kato T, Iizuka H, Yamamoto T. Factors associated with hearing preservation after Gamma Knife surgery for vestibular schwannomas in patients who retain serviceable hearing. J Neurosurg. 2011;115:1078–86.

    Article  Google Scholar 

  38. Hasegawa T, Kida Y, Kato T, Iizuka H, Kuramitsu S, Yamamoto T. Long-term safety and efficacy of stereotactic radiosurgery for vestibular schwannomas: evaluation of 440 patients more than 10 years after treatment with Gamma Knife surgery. J Neurosurg. 2013;118:557–65.

    Article  Google Scholar 

  39. Carlson ML, Jacob JT, Pollock BE, et al. Long-term hearing outcomes following stereotactic radiosurgery for vestibular schwannoma: patterns of hearing loss and variables influencing audiometric decline. J Neurosurg. 2013;118:579–87.

    Article  Google Scholar 

  40. Williams BJ, Xu Z, Salvetti DJ, McNeill IT, Larner J, Sheehan JP. Gamma Knife surgery for large vestibular schwannomas: a single-center retrospective case-matched comparison assessing the effect of lesion size. J Neurosurg. 2013;119:463–71.

    Article  Google Scholar 

  41. Chan AW, Black P, Ojemann RG, et al. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery. 2005;57:60–70.

    Article  Google Scholar 

  42. Wise SC, Carlson ML, Tveiten ØV, et al. Surgical salvage of recurrent vestibular schwannoma following prior stereotactic radiosurgery. Laryngoscope. 2016;126:2580–6.

    Article  Google Scholar 

  43. Coughlin AR, Willman TJ, Gubbels SP. Systematic review of hearing preservation after radiotherapy for vestibular schwannoma. Otol Neurotol. 2018;39:273–83.

    Article  Google Scholar 

  44. Hasegawa T, Kida Y, Kobayashi T, Yoshimoto M, Mori Y, Yoshida J. Long-term outcomes in patients with vestibular schwannomas treated using gamma knife surgery: 10-year follow up. J Neurosurg. 2005;102:10–6.

    Article  Google Scholar 

  45. Jacob JT, Pollock BE, Carlson ML, Driscoll CLW, Link MJ. Stereotactic radiosurgery in the management of vestibular schwannoma and glomus jugulare: indications, techniques, and results. Otolaryngol Clin N Am. 2015;48:515–26.

    Article  Google Scholar 

  46. Jacob JT, Carlson ML, Schiefer TK, Pollock BE, Driscoll CL, Link MJ. Significance of cochlear dose in the radiosurgical treatment of vestibular schwannoma: controversies and unanswered questions. Neurosurgery. 2014;74:466–74.

    Article  Google Scholar 

  47. Massager N, Nissim O, Delbrouck C, et al. Irradiation of cochlear structures during vestibular schwannoma radiosurgery and associated hearing outcome. J Neurosurg. 2007;107:733–9.

    Article  Google Scholar 

  48. Friedman WA, Bradshaw P, Myers A, Bova FJ. Linear accelerator radiosurgery for vestibular schwannomas. J Neurosurg. 2006;105:657–61.

    Article  Google Scholar 

  49. Foote KD, Friedman WA, Buatti JM, Meeks SL, Bova FJ, Kubilis PS. Analysis of risk factors associated with radiosurgery for vestibular schwannoma. J Neurosurg. 2001;95:440–9.

    Article  CAS  Google Scholar 

  50. Spiegelmann R, Lidar Z, Gofman J, Alezra D, Hadani M, Pfeffer R. Linear accelerator radiosurgery for vestibular schwannoma. J Neurosurg. 2001;94:7–13.

    Article  CAS  Google Scholar 

  51. Combs SE, Thilmann C, Debus J, Schulz-Ertner D. Long-term outcome of stereotactic radiosurgery (SRS) in patients with acoustic neuromas. Int J Radiat Oncol Biol Phys. 2006;64:1341–7.

    Article  Google Scholar 

  52. Fukuoka S, Takanashi M, Hojyo A, Konishi M, Tanaka C, Nakamura H. Gamma knife radiosurgery for vestibular schwannomas. Prog Neurol Surg. 2009;22:45–62.

    Article  Google Scholar 

  53. Iwai Y, Yamanaka K, Kubo T, Aiba T. Gamma knife radiosurgery for intracanalicular acoustic neuromas. J Clin Neurosci. 2008;15:993–7.

    Article  Google Scholar 

  54. Kalogeridi M-A, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G. Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: the Greek experience. J Cancer Res Ther. 2009;5:8–13.

    Article  Google Scholar 

  55. Kim K-M, Park C-K, Chung H-T, Paek SH, Jung H-W, Kim DG. Long-term outcomes of gamma knife stereotactic radiosurgery of vestibular schwannomas. J Korean Neurosurg Soc. 2007;42:286–92.

    Article  Google Scholar 

  56. Myrseth E, Moller P, Pedersen P-H, Vassbotn FS, Wentzel-Larsen T, Lund-Johansen M. Vestibular schwannomas: clinical results and quality of life after microsurgery or gamma knife radiosurgery. Neurosurgery. 2005;56:927–35.

    Google Scholar 

  57. Prasad D, Steiner M, Steiner L. Gamma surgery for vestibular schwannoma. J Neurosurg. 2000;92:745–59.

    Article  CAS  Google Scholar 

  58. Unger F, Walch C, Schröttner O, Eustacchio S, Sutter B, Pendl G. Cranial nerve preservation after radiosurgery of vestibular schwannomas. Acta Neurochir Suppl. 2002;84:77–83.

    CAS  Google Scholar 

  59. Linskey ME, Flickinger JC, Lunsford LD. Cranial nerve length predicts the risk of delayed facial and trigeminal neuropathies after acoustic tumor stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 1993;25:227–33.

    Article  CAS  Google Scholar 

  60. Combs SE, Welzel T, Schulz-Ertner D, Huber PE, Debus J. Differences in clinical results after LINAC-based single-dose radiosurgery versus fractionated stereotactic radiotherapy for patients with vestibular schwannomas. Int J Radiat Oncol Biol Phys. 2010;76:193–200.

    Article  Google Scholar 

  61. Murphy ES, Barnett GH, Vogelbaum MA, et al. Long-term outcomes of Gamma Knife radiosurgery in patients with vestibular schwannomas. J Neurosurg. 2011;114:432–40.

    Article  Google Scholar 

  62. Wallner KE, Sheline GE, Pitts LH, Wara WM, Davis RL, Boldrey EB. Efficacy of irradiation for incompletely excised acoustic neurilemomas. J Neurosurg. 1987;67:858–63.

    Article  CAS  Google Scholar 

  63. Maire J-P, Huchet A, Milbeo Y, et al. Twenty years’ experience in the treatment of acoustic neuromas with fractionated radiotherapy: a review of 45 cases. Int J Radiat Oncol Biol Phys. 2006;66:170–8.

    Article  Google Scholar 

  64. Fuss M, Debus J, Lohr F, et al. Conventionally fractionated stereotactic radiotherapy (FSRT) for acoustic neuromas. Int J Radiat Oncol Biol Phys. 2000;48:1381–7.

    Article  CAS  Google Scholar 

  65. Meijer OWM, Vandertop WP, Baayen JC, Slotman BJ. Single-fraction vs. fractionated linac-based stereotactic radiosurgery for vestibular schwannoma: a single-institution study. Int J Radiat Oncol Biol Phys. 2003;56:1390–6.

    Article  CAS  Google Scholar 

  66. Selch MT, Pedroso A, Lee SP, et al. Stereotactic radiotherapy for the treatment of acoustic neuromas. J Neurosurg. 2004;101:362–72.

    Article  Google Scholar 

  67. Combs SE, Volk S, Schulz-Ertner D, Huber PE, Thilmann C, Debus J. Management of acoustic neuromas with fractionated stereotactic radiotherapy (FSRT): long-term results in 106 patients treated in a single institution. Int J Radiat Oncol Biol Phys. 2005;63:75–81.

    Article  Google Scholar 

  68. Kalapurakal JA, Silverman CL, Akhtar N, Andrews DW, Downes B, Thomas PR. Improved trigeminal and facial nerve tolerance following fractionated stereotactic radiotherapy for large acoustic neuromas. Br J Radiol. 1999;72:1202–7.

    Article  CAS  Google Scholar 

  69. Andrews DW, Werner-Wasik M, Den RB, et al. Toward dose optimization for fractionated stereotactic radiotherapy for acoustic neuromas: comparison of two dose cohorts. Int J Radiat Oncol Biol Phys. 2009;74:419–26.

    Article  Google Scholar 

  70. Koh E-S, Millar B-A, Menard C, et al. Fractionated stereotactic radiotherapy for vestibular schwannoma: single institutional experience at the Princess Margaret Hospital. Radiother Oncol. 2005;76:S29.

    Article  Google Scholar 

  71. Thomas C, Di Maio S, Ma R, et al. Hearing preservation following fractionated stereotactic radiotherapy for vestibular schwannomas: prognostic implications of cochlear dose. J Neurosurg. 2007;107:917–26.

    Article  Google Scholar 

  72. Jian BJ, Kaur G, Sayegh ET, Bloch O, Parsa AT, Barani IJ. Fractionated radiation therapy for vestibular schwannoma. J Clin Neurosci. 2014;21:1083–8.

    Article  Google Scholar 

  73. Litre F, Rousseaux P, Jovenin N, et al. Fractionated stereotactic radiotherapy for acoustic neuromas: a prospective monocenter study of about 158 cases. Radiother Oncol. 2013;106:169–74.

    Article  Google Scholar 

  74. Aoyama H, Onodera S, Takeichi N, et al. Symptomatic outcomes in relation to tumor expansion after fractionated stereotactic radiation therapy for vestibular schwannomas: single-institutional long-term experience. Int J Radiat Oncol Biol Phys. 2013;85:329–34.

    Article  Google Scholar 

  75. Nguyen T, Duong C, Sheppard JP, et al. Hypo-fractionated stereotactic radiotherapy of five fractions with linear accelerator for vestibular schwannomas: a systematic review and meta-analysis. Clin Neurol Neurosurg. 2018;166:116–23.

    Article  Google Scholar 

  76. Andrews DW, Suarez O, Goldman HW, et al. Stereotactic radiosurgery and fractionated stereotactic radiotherapy for the treatment of acoustic schwannomas: comparative observations of 125 patients treated at one institution. Int J Radiat Oncol Biol Phys. 2001;50:1265–78.

    Article  CAS  Google Scholar 

  77. Bush DA, Mcallister CJ, Loredo LN, Johnson WD, Slater JM, Slater JD. Fractionated proton beam radiotherapy for acoustic neuroma. Neurosurgery. 2002;50:270–5.

    Google Scholar 

  78. Harsh GR, Thornton AF, Chapman PH, Bussiere MR, Rabinov JD, Loeffler JS. Proton beam stereotactic radiosurgery of vestibular schwannomas. Int J Radiat Oncol Biol Phys. 2002;54:35–44.

    Article  Google Scholar 

  79. Vernimmen FJAI, Mohamed Z, Slabbert JP, Wilson J. Long-term results of stereotactic proton beam radiotherapy for acoustic neuromas. Radiother Oncol. 2009;90:208–12.

    Article  Google Scholar 

  80. Weber DC, Chan AW, Bussiere MR, et al. Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery. 2003;53:577–88.

    Article  Google Scholar 

  81. Tanbouzi Husseini S, Piccirillo E, Taibah A, Paties CT, Rizzoli R, Sanna M. Malignancy in vestibular schwannoma after stereotactic radiotherapy: a case report and review of the literature. Laryngoscope. 2011;121:923–8.

    Article  Google Scholar 

  82. Fusco DJ, Williamson R, Yanamadala V, Eschbacher J, Porter R, Weisskopf P. Malignant transformation of a vestibular schwannoma following gamma knife radiosurgery: case report and review of the literature. J Neurol Surg B Skull Base. 2012;73:A293.

    Article  Google Scholar 

  83. Niranjan A, Kondziolka D, Lunsford LD. Neoplastic transformation after radiosurgery or radiotherapy: risk and realities. Otolaryngol Clin N Am. 2009;42:717–29.

    Article  Google Scholar 

  84. Kondziolka D, Mousavi SH, Kano H, Flickinger JC, Lunsford LD. The newly diagnosed vestibular schwannoma: radiosurgery, resection, or observation? Neurosurg Focus. 2012;33:E8.

    Article  Google Scholar 

  85. Wiet RJ, Mamikoglu B, Odom L, Hoistad DL. Long-term results of the first 500 cases of acoustic neuroma surgery. Otolaryngol Head Neck Surg. 2001;124:645–51.

    Article  CAS  Google Scholar 

  86. Sanna M, Taibah A, Russo A, Falcioni M, Agarwal M. Perioperative complications in acoustic neuroma (vestibular schwannoma) surgery. Otol Neurotol. 2004;25:379–86.

    Article  Google Scholar 

  87. Bambakidis NC, Megerian CA, Spetzler RF. Surgery of the cerebellopontine angle. Shelton, CT: PMPH-USA; 2009.

    Google Scholar 

  88. Ramsden RT. A brilliant surgical result, the first recorded: Annandale’s case, 3 May 1895. J Laryngol Otol. 1995;109:369–73.

    Article  CAS  Google Scholar 

  89. Olson JJ, Kalkanis SN, Ryken TC. Congress of neurological surgeons systematic review and evidence-based guidelines on the treatment of adults with vestibular schwannomas: introduction and methods. Neurosurgery. 2018;82:135.

    Article  Google Scholar 

  90. Parry RH. A case of tinnitus and vertigo treated by division of the auditory nerve. J Laryngol Otol. 1904;19:402–6.

    Article  Google Scholar 

  91. Quix FH. Ein Fall von translabyrintharisch operiertem Tumor acusticus. Verh Dtsch Otol Ges. 1912;21:245–55.

    Google Scholar 

  92. House WF. Transtemporal bone microsurgical removal of acoustic neuromas. Report of cases. Arch Otolaryngol. 1964;80:617–67.

    CAS  Google Scholar 

  93. Dandy WE, et al. An operation for the total removal of cerebellopontine (acoustic) tumors. Surg Gynecol Obstet. 1925;41:129–48.

    Google Scholar 

  94. Dandy WE. Removal of cerebellontine (acoustic) tumors through a unilateral approach. Arch Surg. 1934;29:337–44.

    Article  Google Scholar 

  95. Gonzalez LF, Lekovic GP, Porter RW, Syms MJ, Daspit CP, Spetzler RF. Surgical approaches for resection of acoustic neuromas. Barrow Q. 2004;20:1–11.

    Google Scholar 

  96. Day JD, Chen DA, Arriaga M. Translabyrinthine approach for acoustic neuroma. Neurosurgery. 2004;54:391–6.

    Article  Google Scholar 

  97. Nakatomi H, Jacob JT, Carlson ML, et al. Long-term risk of recurrence and regrowth after gross-total and subtotal resection of sporadic vestibular schwannoma. J Neurosurg. 2017;19:1–7.

    Google Scholar 

  98. Jacob JT, Carlson ML, Driscoll CL, Link MJ. Volumetric analysis of tumor control following subtotal and near-total resection of vestibular schwannoma. Laryngoscope. 2016;126:1877–82.

    Article  CAS  Google Scholar 

  99. Yamakami I, Uchino Y, Kobayashi E, Yamaura A. Conservative management, gamma-knife radiosurgery, and microsurgery for acoustic neurinomas: a systematic review of outcome and risk of three therapeutic options. Neurol Res. 2003;25:682–90.

    Article  Google Scholar 

  100. Monfared A, Corrales CE, Theodosopoulos PV, et al. Facial nerve outcome and tumor control rate as a function of degree of resection in treatment of large acoustic neuromas: preliminary report of the acoustic neuroma subtotal resection study (ANSRS). Neurosurgery. 2016;79:194–203.

    Article  Google Scholar 

  101. Mangham CA Jr. Retrosigmoid versus middle fossa surgery for small vestibular schwannomas. Laryngoscope. 2004;114:1455–61.

    Article  Google Scholar 

  102. Sanna M, Khrais T, Russo A, Piccirillo E, Augurio A. Hearing preservation surgery in vestibular schwannoma: the hidden truth. Ann Otol Rhinol Laryngol. 2004;113:156–63.

    Article  Google Scholar 

  103. Samii M, Matthies C. Management of 1000 vestibular schwannomas (acoustic neuromas): hearing function in 1000 tumor resections. Neurosurgery. 1997;40:248–62.

    Article  CAS  Google Scholar 

  104. McElveen JT Jr, Belmonte RG, Fukushima T, Bullard DE. A review of facial nerve outcome in 100 consecutive cases of acoustic tumor surgery. Laryngoscope. 2000;110:1667–72.

    Article  Google Scholar 

  105. Colletti V, Fiorino F. Middle fossa versus retrosigmoid-transmeatal approach in vestibular schwannoma surgery: a prospective study. Otol Neurotol. 2003;24:927–34.

    Article  Google Scholar 

  106. Arts HA, Telian SA, El-Kashlan H, Thompson BG. Hearing preservation and facial nerve outcomes in vestibular schwannoma surgery: results using the middle cranial fossa approach. Otol Neurotol. 2006;27:234–41.

    Article  Google Scholar 

  107. Fenton JE, Chin RY, Fagan PA, Sterkers O, Sterkers JM. Predictive factors of long-term facial nerve function after vestibular schwannoma surgery. Otol Neurotol. 2002;23:388–92.

    Article  Google Scholar 

  108. Lanman TH, Brackmann DE, Hitselberger WE, Subin B. Report of 190 consecutive cases of large acoustic tumors (vestibular schwannoma) removed via the translabyrinthine approach. J Neurosurg. 1999;90:617–23.

    Article  CAS  Google Scholar 

  109. Hadjipanayis CG, Carlson ML, Link MJ, et al. Congress of neurological surgeons systematic review and evidence-based guidelines on surgical resection for the treatment of patients with vestibular schwannomas. Neurosurgery. 2018;82:E40–3.

    Article  Google Scholar 

  110. Copeland WR, Mallory GW, Neff BA, Driscoll CLW, Link MJ. Are there modifiable risk factors to prevent a cerebrospinal fluid leak following vestibular schwannoma surgery? J Neurosurg. 2015;122:312–6.

    Article  Google Scholar 

  111. Murphy ME, McCutcheon BA, Kerezoudis P, et al. Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. Clin Neurol Neurosurg. 2016;148:105–9.

    Article  Google Scholar 

  112. Selesnick SH, Liu JC, Jen A, Carew JF. Management options for cerebrospinal fluid leak after vestibular schwannoma surgery and introduction of an innovative treatment. Otol Neurotol. 2004;25:580–6.

    Article  Google Scholar 

  113. Alattar AA, Hirshman BR, McCutcheon BA, et al. Risk factors for readmission with cerebrospinal fluid leakage within 30 d of vestibular schwannoma surgery. Neurosurgery. 2018;82:630–7. https://doi.org/10.1093/neuros/nyx197.

    Article  Google Scholar 

  114. Isaacson JE. Radiologic follow-up after vestibular schwannoma surgery. Otol Neurotol. 2005;26:552.

    Google Scholar 

  115. Costantino PD, Hiltzik DH, Sen C, et al. Sphenoethmoid cerebrospinal fluid leak repair with hydroxyapatite cement. Arch Otolaryngol Head Neck Surg. 2001;127:588–93.

    Article  CAS  Google Scholar 

  116. Gauden A, Weir P, Hawthorne G, Kaye A. Systematic review of quality of life in the management of vestibular schwannoma. J Clin Neurosci. 2011;18:1573–84.

    Article  Google Scholar 

  117. Gouveris HT, Mann WJ. Quality of life in sporadic vestibular schwannoma: a review. ORL J Otorhinolaryngol Relat Spec. 2010;72:69–74.

    Article  Google Scholar 

  118. Martin HC, Sethi J, Lang D, Neil-Dwyer G, Lutman ME, Yardley L. Patient-assessed outcomes after excision of acoustic neuroma: postoperative symptoms and quality of life. J Neurosurg. 2001;94:211–6.

    Article  CAS  Google Scholar 

  119. Nicoucar K, Momjian S, Vader J-P, De Tribolet N. Surgery for large vestibular schwannomas: how patients and surgeons perceive quality of life. J Neurosurg. 2006;105:205–12.

    Article  Google Scholar 

  120. Shaffer BT, Cohen MS, Bigelow DC, Ruckenstein MJ. Validation of a disease-specific quality-of-life instrument for acoustic neuroma: the Penn Acoustic Neuroma Quality-of-Life Scale. Laryngoscope. 2010;120:1646–54.

    Article  Google Scholar 

  121. Di Maio S, Akagami R. Prospective comparison of quality of life before and after observation, radiation, or surgery for vestibular schwannomas. J Neurosurg. 2009;111:855–62.

    Article  Google Scholar 

  122. Breivik CN, Varughese JK, Wentzel-Larsen T, Vassbotn F, Lund-Johansen M. Conservative management of vestibular schwannoma—a prospective cohort study: treatment, symptoms, and quality of life. Neurosurgery. 2012;70:1072–80.

    Article  Google Scholar 

  123. Myrseth E, Møller P, Pedersen P-H, Lund-Johansen M. Vestibular schwannoma: surgery or gamma knife radiosurgery? A prospective, nonrandomized study. Neurosurgery. 2009;64:654–63.

    Article  Google Scholar 

  124. Pollock BE, Driscoll CLW, Foote RL, et al. Patient outcomes after vestibular schwannoma management: a prospective comparison of microsurgical resection and stereotactic radiosurgery. Neurosurgery. 2006;59:77–85.

    Google Scholar 

  125. Carlson ML, Tveiten OV, Driscoll CL, Goplen FK. Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery. J Neurosurg. 2015;122:833–42.

    Article  Google Scholar 

  126. Soulier G, van Leeuwen BM, Putter H, et al. Quality of life in 807 patients with vestibular schwannoma: comparing treatment modalities. Otolaryngol Head Neck Surg. 2017;157:92–8.

    Article  Google Scholar 

  127. Link MJ, Lund-Johansen M, Lohse CM, et al. Quality of life in patients with vestibular schwannomas following gross total or less than gross total microsurgical resection: should we be taking the entire tumor out? Neurosurgery. 2018;82:541–7.

    Article  Google Scholar 

  128. Carlson ML, Tveiten ØV, Yost KJ, Lohse CM, Lund-Johansen M, Link MJ. The minimal clinically important difference in vestibular schwannoma quality-of-life assessment: an important step beyond P < .05. Otolaryngol Head Neck Surg. 2015;153:202–8.

    Article  Google Scholar 

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Kerezoudis, P., Weisskopf, P.A., Driscoll, C.L.W., Link, M.J. (2022). Treatment Options for Acoustic Neuroma, Including Stereotactic Radiosurgery. In: Bambakidis, N.C., Megerian, C.A., Spetzler, R.F. (eds) Surgery of the Cerebellopontine Angle. Springer, Cham. https://doi.org/10.1007/978-3-031-12507-2_10

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