Skip to main content

Dental Comorbidities and Risk Factors of Sleep-Disordered Breathing

  • Chapter
  • First Online:
Dental Sleep Medicine

Abstract

Sleep-related breathing disorders refer to several pathologies, which include snoring, upper airway resistance syndrome, and obstructive sleep apnea. The pathophysiology of OSA is characterized by repetitive oropharyngeal collapse and occlusions during sleep, which obstructs the airway. It is associated with sleep fragmentation, hypoxemia, hypercapnia, marked swings in intrathoracic pressure, increased sympathetic activity and inflammatory markers and cytokines, and cardiovascular complications.

The prevalence of OSA in the adult population is estimated to be between 2 and 4%, with the major factors being age, sex, and weight. There are multiple structural, orthopedic, and physical contributing factors for OSA. Neck size and intraoral structures are common factors that contribute to the collapse of the oropharyngeal structures. These factors can include elongation of the soft palate and uvula from the pulling forces due to snoring and loss of vertical dimension shortening the lower one-third of the face. OSA can be influenced by bruxism, resulting in attrition of teeth, extraction of teeth causing a loss in jaw support, increase in tongue size due to fat deposition in the tongue, constriction of dental arches due to extraction of first bicuspids during orthodontics, and negative transmural pressure gradient and tissue weight.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

AHI:

Apnea-hypopnea index

BMI:

Body mass index

DSA:

Dental sleep appliance

HH:

Hypnic headache

OAT:

Oral appliance therapy

OHS:

Obstructive hypopnea syndrome

OSA:

Obstructive sleep apnea

RDI:

Respiratory distress index

REM:

Rapid eye movement

RERA:

Respiratory effort-related arousal

RME:

Rapid maxillary expansion

SB:

Sleep bruxism

SRBD:

Sleep-related breathing disorder

T&A:

Adenotonsillectomy

TMD:

Temporomandibular joint dysfunction

TTH:

Tension-type headache

UARS:

Upper airway resistance syndrome

VDO:

Vertical dimension of occlusion

References

  1. Epstein LJ, Kristo D, Strollo PJ, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263–76.

    Article  PubMed  Google Scholar 

  2. Demerjian GG, Goel P. Immunologic and physiologic effects of dental sleep appliance therapy. In: Temporomandibular joint and airway disorders. Cham: Springer Nature; 2018.

    Chapter  Google Scholar 

  3. Dinges DF, Douglas SD, Zaugg L, Campbell DE, Mcmann JM, Whitehouse WG, et al. Leukocytosis and natural-killer-cell function parallel neurobehavioral fatigue-induced by 64 hours of sleep-deprivation. J Clin Investig. 1994;93:1930–9.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Alberti A, Sarchielli P, Gallinella E, Floridi A, Floridi A, Mazzotta G, et al. Plasma cytokine levels in patients with obstructive sleep apnea syndrome: a preliminary study. J Sleep Res. 2003;12:305–11. https://doi.org/10.1111/j.1365-2869.2003.00361.x.

    Article  PubMed  Google Scholar 

  5. Bouloukaki I, Papadimitriou V, Sofras F, Mermigkis C, Moniaki V, Siafakas NM, et al. Abnormal cytokine profile in patients with obstructive sleep apnea–hypopnea syndrome and erectile dysfunction. Mediators Inflamm. 2014;2014:68951. https://doi.org/10.1155/2014/568951.

    Article  Google Scholar 

  6. Carpagnano GE, Spanevello A, Sabato R, Depalo A, Palladino GP, Bergantino L, et al. Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8. Transl Res. 2010;155:35–43. https://doi.org/10.1016/j.trsl.2009.09.004.

    Article  PubMed  Google Scholar 

  7. Ciftci TU, Kokturk O, Bukan N, Bilgihan A. The relationship between serum cytokine levels with obesity and obstructive sleep apnea syndrome. Cytokine. 2004;28:87–91. https://doi.org/10.1016/j.cyto.2004.07.003.

    Article  PubMed  Google Scholar 

  8. Yokoe T, Minoguchi K, Matsuo H, Oda N, Minoguchi H, Yoshino G, et al. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation. 2003;107:1129–34. https://doi.org/10.1161/01.CIR.0000052627.99976.18.

    Article  PubMed  Google Scholar 

  9. Tobin M. Sleep-disordered breathing, control of breathing, respiratory muscles, and pulmonary function testing in AJRCCM 2001. Am J Respir Crit Care Med. 2002;165:584–97.

    Article  PubMed  Google Scholar 

  10. Coleman RM, Roffwarg HP, Kennedy SJ, Guilleminault C, Cinque J, Cohn MA, Karacan I, Kupfer DJ, Lemmi H, Miles LE. Sleep–wake disorders based on a polysomnographic diagnosis: a national cooperative study. JAMA. 1982;247:997–1003.

    Article  PubMed  Google Scholar 

  11. Black AJ, Boysen PG, Wynne JW, Hunt LA. Sleep apnea, hypopnea and oxygen desaturation in normal subjects: a strong male predominance. N Engl J Med. 1979;300:513–7.

    Article  Google Scholar 

  12. Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto J, Stubbs R, Hla KM. Sleep disordered breathing and mortality: 18-year follow-up of the Wisconsin sleep cohort. Sleep. 2008;31(8):1071–8. https://doi.org/10.5665/sleep/31.8.1071.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Rotem AY, Sperber AD, Krugliak P, Freidman B, Tal A, Tarasiuk A. Polysomnographic and actigraphic evidence of sleep fragmentation in patients with irritable bowel syndrome. Sleep. 2003;26(6):747–52. https://doi.org/10.1093/sleep/26.6.747.

    Article  PubMed  Google Scholar 

  14. Kim AM, Keenan BT, Jackson N, Chan EL, Staley B, Poptani H, Torigian DA, Pack AI, Schwab RJ. Tongue fat and its relationship to obstructive sleep apnea. Sleep. 2014;37(10):1639–48. https://doi.org/10.5665/sleep.4072.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Sands SA, Eckert DJ, Jordan AS, Edwards BA, Owens RL, Butler JP, Schwab RJ, Loring SH, Malhotra A, White DP, Wellman A. Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea. Am J Respir Crit Care Med. 2014;190(8):15. https://doi.org/10.1164/rccm.201404-0783OC.

    Article  Google Scholar 

  16. Pirila-Parkinen K, Prittiniemi P, Nieminin P, Tolonen U, Pelttari U, Lopponen H. Dental arch morphology in children with sleep-disordered breathing. Eur J Orthod. 2009;31(2):160–7.

    Article  Google Scholar 

  17. Hendricks JC, Petrof BJ, Panckeri K, Pack AI. Upper airway dilating muscle hyperactivity during non-rapid eye movement sleep in bulldogs. Am Rev Respir Dis. 1993;148:185–94. https://doi.org/10.1093/ejo/cjn061.

    Article  PubMed  Google Scholar 

  18. Series F, Cote C, Simonea JA, Gelinas Y, St. Pierre S, Leclerc J, Ferland R, Marc I. Physiologic and metabolic profile of musculus uvulae in sleep apnea syndrome and in snorers. J Clin Investig. 1995;95:20–5. https://doi.org/10.1172/JCI117640.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Series F, Cote C, St. Pierre S. Dysfunctional mechanical coupling of upper airway tissues in sleep apnea syndrome. Am J Respir Crit Care Med. 1999;159:1551–5. https://doi.org/10.1164/ajrccm.159.5.9804124.

    Article  PubMed  Google Scholar 

  20. Sekosan C, Zakkar M, Wenig BL, Olopade CO, Rubinstein I. Inflammation in the uvula mucosa of patients with obstructive sleep apnea. Laryngoscope. 1996;106:1018–20.

    Article  PubMed  Google Scholar 

  21. Casale M, Pappacena M, Rinaldi V, Bressi F, Baptista P, Salvinellii F. Obstructive sleep apnea syndrome: from phenotype to genetic basis. Curr Genomics. 2009;10:119–26. https://doi.org/10.1097/00005537-199608000-00021.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Punjabi NM, Caffo BS, Goodwin JL, et al. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med. 2009;6(8):e1000132. https://doi.org/10.1371/journal.pmed.1000132.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Berry RB, Rudhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, SLD W, Tangredi MM. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. J Clin Sleep Med. 2012;8(5):597–619. https://doi.org/10.5664/jcsm.2172.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Lavigne GJ, Cistulli PA, Smith MT. Sleep medicine for dentists. Chicago: Quintessence; 2009.

    Google Scholar 

  25. Dempsey JA, Veasey SC, Morgan BJ, O’Donnel CP. Pathophysiology of sleep apnea. Physiol Rev. 2010;90(1):47–112. https://doi.org/10.1152/physrev.00043.2008.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Hiwa M, Rezaei M, Faghihi F, Khazaie H. Hypothalamic–pituitary–gonadal activity in paradoxical and psychophysiological insomnia. J Med Signals Sens. 2019;9(1):59–67.

    Article  Google Scholar 

  27. Davila DG. Allergies and sleep. 2017. Sleepfoundation.org. Accessed 18 May 2017.

    Google Scholar 

  28. Johns M. About the ESS—Epworth sleepiness scale. 2017. EpworthSleepinessScale.com. Accessed 30 May 2017.

    Google Scholar 

  29. Dweik RA, Laskowski D, Husam M, Abu-Soud HM, Kaneko FT, Hutte R, Dennis J, Stuehr DJ. Nitric oxide synthesis in the lung regulation by oxygen through a kinetic mechanism. J Clin Investig. 1998;101(3):660–6.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Valcheva Z, Arnautska H, Dimova M, Ivanova G, Atanasova I. The role of mouth breathing on dentition development and formation. J IMAB Annu Proc (Sci Pap). 2018;24(1):1878–82. https://doi.org/10.5272/jimab.2018241.1878.

    Article  Google Scholar 

  31. Pacheco MC, Casagrande CF, Teixeira LP, Finck NS, Martins de Araújo MT. Guidelines proposal for clinical recognition of mouth breathing children. Dent Press J Orthod. 2015;20(4):39–44. https://doi.org/10.1590/2176-9451.20.4.039-044.oar.

    Article  Google Scholar 

  32. Izu SC, Itamoto CH, Pradella-Hallinan M, Pizarro GU, Tufik S, Pignatari S, Fujita RR. Obstructive sleep apnea syndrome (OSAS) in mouth breathing children. Braz J Otorhinolaryngol. 2010;76(5):552–6. https://doi.org/10.1590/S1808-86942010000500003.

    Article  PubMed  Google Scholar 

  33. Gozal D. Sleep-disordered breathing and school performance in children. Pediatrics. 1998;102:616–20. https://doi.org/10.1542/peds.102.3.616.

    Article  PubMed  Google Scholar 

  34. Weissbluth M, Davis AT, Poncher J, Reiff J. Signs of airway obstruction during sleep and behavioral, developmental, and academic problems. J Dev Behav Pediatr. 1983;4:119–21.

    Article  PubMed  Google Scholar 

  35. Bar A, Tarasiuk A, Segev Y, Phillip M, Tal A. The effect of adenotonsillectomy on serum insulin-like growth factor-I and growth in children with obstructive sleep apnea syndrome. J Pediatr. 1999;135:76–80. https://www.researchgate.net/publication/12904877.

    Article  PubMed  Google Scholar 

  36. Foster GD, Borradaile KE, Sanders MH, et al. A randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes: the sleep AHEAD study. Arch Intern Med. 2009;169:1619–26.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177:1006–14. https://doi.org/10.1093/aje/kws342.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Nashi N, Kang S, Barkdull GC, Lucas J, Davidson TM. Lingual fat at autopsy. Laryngoscope. 2007;117:1467–73. https://doi.org/10.1097/MLG.0b013e318068b566.

    Article  PubMed  Google Scholar 

  39. Kovanlikaya A, Guclu C, Desai C, Becerra R, Gilsanz V. Fat quantification using three-point Dixon technique: in vitro validation. Acad Radiol. 2005;12:636–9. https://doi.org/10.1016/j.acra.2005.01.019.

    Article  PubMed  Google Scholar 

  40. Eckert DJ, Lo YL, Saboisky JP, Jordan AS, White DP, Malhotra A. Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea. J Appl Physiol. 2011;111:1644–53. https://doi.org/10.1152/japplphysiol.00653.2011.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Shelton KE, Woodson H, Gay S, Suratt PM. Pharyngeal fat in obstructive sleep apnea. Am Rev Respir Dis. 1993;148:462–6. https://doi.org/10.1164/ajrccm/148.2.462.

    Article  PubMed  Google Scholar 

  42. Schwab RJ, Pasirstein M, Pierson R, et al. Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. Am J Respir Crit Care Med. 2003;168:522–30. https://doi.org/10.1164/rccm.200208-866OC.

    Article  PubMed  Google Scholar 

  43. Li Y, Na L, Ye J, Chang Q, Han D, Sperry A. Upper airway fat tissue distribution differences in patients with obstructive sleep apnea and controls as well as its effect on retropalatal mechanical loads. Respir Care. 2012;57:1098–105. https://doi.org/10.4187/respcare.00929.

    Article  PubMed  Google Scholar 

  44. Guimaraes KC, Drager LF, Genta PR, Marcondes BF, Lorenzi-Filho G. Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome. Am J Respir Crit Care Med. 2009;179:962–6. https://doi.org/10.1164/rccm.200806-981OC.

    Article  PubMed  Google Scholar 

  45. Weiss TM, Atanasov S, Calhoun KH. The association of tongue scalloping with obstructive sleep apnea and related sleep pathology. Otolaryngol Head Neck Surg. 2005;133(6):966–71. https://doi.org/10.1016/j.otohns.2005.07.018.

    Article  PubMed  Google Scholar 

  46. Ohayon MM, Li KK, Guilleminault C. Risk factors for sleep bruxism in the general population. Chest. 2001;119(1):53–61.

    Article  PubMed  Google Scholar 

  47. Lobbezoo F, Ahlberg J, Raphael KG, Wetselaar P, Glaros AG, Kato T, Santiago V, Winocur E, De Laat A, De Leeuw R, Koyano K, Lagigine GJ, Svensson P, Manfredini D. International consensus on the assessment of bruxism: report of a work in progress. J Oral Rehabil. 2018;2018:12663. https://doi.org/10.1111/joor.12663.

    Article  Google Scholar 

  48. de Leeuw R, Klasser GD. Sixth edition orofacial pain: guidelines for assessment, diagnosis, and management/American Academy of Orofacial Pain. 6th ed. Chicago: Quintessence; 2018.

    Google Scholar 

  49. Seligman DA, Pullinger AG, Solberg WK. The prevalence of dental attrition and its association with factors of age, gender, occlusion, and TMJ symptomatology. J Dent Res. 1988;67(10):1323–33.

    Article  PubMed  Google Scholar 

  50. Hollowell DE, Suratt PM. Activation of masseter muscles with inspiratory resistance loading. J Appl Physiol. 1989;67(1):270–5.

    Article  PubMed  Google Scholar 

  51. Hollowell DE, Bhandary PR, Funsten AW, Suratt PM. Respiratory-related recruitment of the masseter: response to hypercapnia and loading. J Appl Physiol. 1991;70(6):2508–13.

    Article  PubMed  Google Scholar 

  52. Michael JA, Townsend GC, Greenwood LF, Kaidonis JA. Abfraction: separating fact from fiction. Aust Dent J. 2009;54:2–8. https://doi.org/10.1111/j.1834-7819.2008.01080.x.

    Article  PubMed  Google Scholar 

  53. El-Marakby AM, Al-Sabri FA, Alharbi SA, Halawani SM, Yousef MTB. Noncarious cervical lesions as abfraction: etiology, diagnosis, and treatment modalities of lesions: a review article. Dentistry. 2017;7:438.

    Article  Google Scholar 

  54. Pearson OM, Lieberman DE. The aging of Wolff’s “law”: ontogeny and responses to mechanical loading in cortical bone. Am J Phys Anthropol. 2004;47:63–99. https://doi.org/10.1002/ajpa.20155.

    Article  Google Scholar 

  55. Singh GD. On the etiology and significance of palatal and mandibular tori. Cranio. 2010;28(4):213–5. https://doi.org/10.1179/crn.2010.030.

    Article  PubMed  Google Scholar 

  56. Moss ML. The functional matrix hypothesis revisited. 2. The role of an Osseous connection cellular network. Am J Orthod Dentofacial Orthop. 1997;112(2):221–6. https://doi.org/10.1016/S0889-5406(97)70249-X.

    Article  PubMed  Google Scholar 

  57. Kerdpon D, Sirirungrojying S. A clinical study of oral tori in southern Thailand: prevalence and the relation to parafunctional activity. Eur J Oral Sci. 1999;107:9–13. https://doi.org/10.1038/sj.bdj.4800209.

    Article  PubMed  Google Scholar 

  58. Palm E, Franklin KA, Marklund M. Mandibular tori size is related to obstructive sleep apnea and treatment success with an oral appliance. Sleep Breath. 2014;18:431–8. https://doi.org/10.1007/s11325-013-0905-5.

    Article  PubMed  Google Scholar 

  59. Seah YH. Torus palatinus and torus mandibular is: a review of the literature. Aust Dent J. 1995;40(5):318–21. https://doi.org/10.1111/j.1834-7819.1995.tb04820.x.

    Article  PubMed  Google Scholar 

  60. Ruangsri S, Jorns TP, Puasiri S, Luecha T, Chaithap C, Sawanyawisuth K. Which oropharyngeal factors are significant factors for obstructive sleep apnea? An age-matched study and dentist perspectives. Nat Sci Sleep. 2016;8:215–9.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Douglass JB, Meader L, Kaplan A, Ellinger CW. Cephalometric evaluation of the changes in patients wearing complete dentures: a 20-year study. J Prosthet Dent. 1993;69(3):270–5. https://doi.org/10.1016/0022-3913(93)90105-W.

    Article  PubMed  Google Scholar 

  62. Bucca C, Carossa S, Colagrande P, Brussino L, Chiavassa G, Pera P, Rolla G, Preti G. Effect of edentulism on spirometric tests. Am J Respir Crit Care Med. 2001;162:1018–20. https://doi.org/10.1164/ajrccm.163.4.2005022.

    Article  Google Scholar 

  63. Bucca C, Cicolin A, Brussino L, et al. Tooth loss and obstructive sleep apnoea. Respir Res. 2006;7:8. https://doi.org/10.1186/1465-9921-7-8.

    Article  PubMed  PubMed Central  Google Scholar 

  64. Shigeta Y, Ogawa T, Tomoko I, Clark GT. Soft palate length and upper airway relationship in OSA and non-OSA subjects. Sleep Breath. 2010;14(4):353–8. https://doi.org/10.1007/s11325-009-0318-7.

    Article  PubMed  Google Scholar 

  65. Chang ET, Baik G, Torre C, Brietzke SE, Camacho M. The relationship of the uvula with snoring and obstructive sleep apnea: a systematic review. Sleep Breath. 2018;22:955–61. https://doi.org/10.1007/s11325-018-1651-5.

    Article  PubMed  Google Scholar 

  66. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002;165:1217–39.

    Article  PubMed  Google Scholar 

  67. Arens R, Marcus CL. Pathophysiology of upper airway obstruction: a developmental perspective. Sleep. 2004;27:997–1019. https://doi.org/10.1093/sleep/27.5.997.

    Article  PubMed  Google Scholar 

  68. Schechter MS, Section on Pediatric Pulmonology, Subcommittee on Obstructive Sleep Apnea Syndrome. Technical report: diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2002;109:e69.

    Article  PubMed  Google Scholar 

  69. Tal A, Leiberman A, Margulis G, Sofer S. Ventricular dysfunction in children with obstructive sleep apnea: radionuclide assessment. Pediatr Pulmonol. 1988;4:139–43.

    Article  PubMed  Google Scholar 

  70. Valcheva Z, Arnautska H, Dimova M, Ivanova G, Atanasova I. The role of mouth breathing on dentition development and formation. J IMAB. 2017;23(4):1878. https://doi.org/10.5272/jimab.2018241.1878.

    Article  Google Scholar 

  71. Hu Z, Yin X, Liao J, Zhou C, Yang Z, Zou S. The effect of teeth extraction for orthodontic treatment on the upper airway: a systematic review. Sleep Breath. 2015;19(2):441–51. https://doi.org/10.1007/s11325-015-1122-1.

    Article  PubMed  Google Scholar 

  72. Tsuchia M, Lowe AA, Pae EK, Fleetham JA. Obstructive sleep apnea subtypes by cluster analysis. Am J Orthod Dentofacial Orthop. 1992;101:533–42. https://doi.org/10.1016/0889-5406(92)70128-W.

    Article  Google Scholar 

  73. Germec-Cakan D, Taner T, Akan S. Uvulo-glossopharyngeal dimensions in non-extraction, extraction with minimum anchorage, and extraction with maximum anchorage. Eur J Orthod. 2011;33(5):515–20. https://doi.org/10.1093/ejo/cjq109.

    Article  PubMed  Google Scholar 

  74. Nargozian C. The airway in patients with craniofacial abnormalities. Pediatr Anesth. 2004;14(1):53–9.

    Article  Google Scholar 

  75. Handler SD. Upper airway obstruction in craniofacial anomalies: diagnosis and management. Birth Defects Orig Artic Ser. 1985;21(2):15–31.

    PubMed  Google Scholar 

  76. Hui S, Wing YK, Kew J, Chan YL, Abdullah V, Fok TF. Obstructive sleep apnea syndrome in a family with Crouzon’s syndrome. Sleep. 1998;21(3):298–303.

    PubMed  Google Scholar 

  77. Valiathan M, El H, Hans MG, Palomo MJ. Effects of extraction versus non-extraction treatment on oropharyngeal airway volume. Angle Orthod. 2010;80(6):1068–74. https://doi.org/10.2319/010810-19.1.

    Article  PubMed  PubMed Central  Google Scholar 

  78. Demko BG. Ten misconceptions that dentists have about treating obstructive sleep apnea. J Dent Sleep Med. 2018;5(3):7036. https://www.researchgate.net/publication/326306674.

    Article  Google Scholar 

  79. Larsen AJ, Rindal DB, Hatch JP, et al. Evidence supports no relationship between obstructive sleep apnea and premolar extraction: an electronic health records review. J Clin Sleep Med. 2015;11(12):10–5. https://doi.org/10.5664/jcsm.5284.

    Article  Google Scholar 

  80. Huang Y-S, Guilleminault C, Lee C-H, Hwang F-M. Treatment outcomes of adenotonsillectomy for children with obstructive sleep apnea: a prospective longitudinal study. Sleep. 2014;37(1):71–6. https://doi.org/10.5665/sleep.3310.

    Article  PubMed  PubMed Central  Google Scholar 

  81. Villa MP, Rizzoli A, Miano S, Malagola C. Efficacy of rapid maxillary expansion in children with obstructive sleep apnea syndrome: 36 months of follow-up. Sleep Breath. 2011;15:179–84. https://doi.org/10.1007/s11325-011-0505-1.

    Article  PubMed  Google Scholar 

  82. Pirelli P, Saponara M, Guilleminault C. Rapid maxillary expansion in children with obstructive sleep apnea syndrome. Sleep Med. 2004;27(4):761–6. https://doi.org/10.1093/sleep/27.4.761.

    Article  Google Scholar 

  83. Pirelli P, Saponara M, Guilleminault C. Rapid maxillary expansion (RME) for pediatric obstructive sleep apnea: a 12-year follow-up. Sleep Med. 2015;16(8):933–5. https://doi.org/10.1016/j.sleep.2015.04.012.

    Article  PubMed  Google Scholar 

  84. Quo SD, Hyunh N, Guilleminault C. Bimaxillary expansion therapy for pediatric sleep-disordered breathing. Sleep Med. 2017;30:45–51. https://doi.org/10.1016/j.sleep.2016.03.011.

    Article  PubMed  Google Scholar 

  85. Bach N, Tuomilehto H, Gauthier C, Papadakis A, et al. The effect of surgically assisted rapid maxillary expansion on sleep architecture: an exploratory risk study in healthy young adults. J Oral Rehabil. 2013;40(11):818–25. https://doi.org/10.1111/joor.12102.

    Article  PubMed  Google Scholar 

  86. Vinha PP, Eckeli AL, Faria AC, Xavier SP, de Mello-Filho FV. Effects of surgically assisted rapid maxillary expansion on obstructive sleep apnea and daytime sleepiness. Sleep Breath. 2016;20(2):501–8. https://doi.org/10.1007/s11325-015-1214-y.

    Article  PubMed  Google Scholar 

  87. Merrill RL. Temporomandibular disorder pain and dental treatment of obstructive sleep apnea. Dent Clin. 2012;56(2):415–31. https://doi.org/10.1016/j.cden.2012.01.004.

    Article  Google Scholar 

  88. Yatani H, Studts J, Cordova M, Carlson CR, Okeson JP. Comparison of sleep quality and clinical and psychologic characteristics in patients with temporomandibular disorders. J Orofac Pain. 2002;16:221–8.

    PubMed  Google Scholar 

  89. Quartana PJ, Wickwire EM, Klick B, Grace E, Smith MT. Naturalistic changes in insomnia symptoms and pain in temporomandibular joint disorder: a cross-lagged panel analysis. Pain. 2010;149:325–31.

    Article  PubMed  Google Scholar 

  90. Cunali PA, Almeida FR, Santos CD, Valdrighi NY, Nascimento LS, Dal'Fabbro C, Tufik S, Bittencourt LR. Prevalence of temporomandibular disorders in obstructive sleep apnea patients referred for oral appliance therapy. J Orofac Pain. 2009;23(4):339–44. https://www.researchgate.net/publication/38066249.

    PubMed  Google Scholar 

  91. Sanders AE, Essick GK, Fillingim R, Knott C, Ohrbach R, Greenspan JD, Diatchenko L, Maixner W, Dubner R, Bair E, Miller VE. Sleep apnea symptoms and risk of temporomandibular disorder: OPPERA cohort. J Dent Res. 2013;92(7_suppl):S70–7.

    Article  PubMed Central  Google Scholar 

  92. Smith MT, Wickwire EM, Grace EG, Edwards RR, Buenaver LF, Peterson S, Klick B, Haythornthwaite JA. Sleep disorders and their association with laboratory pain sensitivity in temporomandibular joint disorder. Sleep. 2009;32(6):779–90.

    Article  PubMed  PubMed Central  Google Scholar 

  93. Schiffman E, Ohrbach R, Truelove E, et al. Diagnostic criteria for temporomandibular disorders (DC/TMD) for clinical and research applications: recommendations of the international RDC/TMD consortium network and orofacial pain special interest group. J Oral Facial Pain Headache. 2014;28:6–27.

    Article  PubMed  PubMed Central  Google Scholar 

  94. Dubrovsky B, Raphael KG, Lavigne GJ, Janal MN, Sirois DA, Wigren PE, Nemelivsky LV, Klausner JJ, Krieger AC. Polysomnographic investigation of sleep and respiratory parameters in women with temporomandibular pain disorders. J Clin Sleep Med. 2014;10(2):195–201.

    Article  PubMed  PubMed Central  Google Scholar 

  95. Turk DC, Rudy TE. Toward an empirically derived taxonomy of chronic pain patients: integration of psychological assessment data. J Consult Clin Psychol. 1988;56:233–8.

    Article  PubMed  Google Scholar 

  96. Martínez-Gomis J, Willaert E, Nogues L, Pascual M, Somoza M, Monasterio C. Five years of sleep apnea treatment with a mandibular advancement device. Side effects and technical complications. Angle Orthod. 2010;80(1):30–6. https://doi.org/10.2319/030309-122.1.

    Article  PubMed  PubMed Central  Google Scholar 

  97. Gupta R, Mansoor AD. Catathrenia: a rare disorder presenting as daytime sleepiness and headache. Neurol India. 2017;65(3):633.

    Article  PubMed  Google Scholar 

  98. Olesen J, Bes A, Kunkel R, Lance JW, Nappi G, Pfaffenrath V, Rose FC, Schoenberg BS, Soyka D, Tfelt-Hansen P, Welch KM. The international classification of headache disorders, 3rd edition (beta version). Cephalalgia. 2013;33(9):629–808.

    Article  Google Scholar 

  99. Holle D, Naegel S, Obermann M. Hypnic headache. Cephalalgia. 2013;33(16):1349–57. https://doi.org/10.1177/0333102413495967.

    Article  PubMed  Google Scholar 

  100. Lanteri-Minet M. Hypnic headache. Headache. 2014;18:12447. https://doi.org/10.1111/head.12447.

    Article  Google Scholar 

  101. Chiu Y, Hu H, Lee F, Huang H. Tension-type headache associated with obstructive sleep apnea: a nationwide population-based study. J Headache Pain. 2015;16:34. https://doi.org/10.1186/s10194-015-0517-5.

    Article  PubMed  PubMed Central  Google Scholar 

  102. Vendrame M, Kaleyias J, Valencia I, Legido A, Kothare SV. Polysomnographic findings in children with headaches. Pediatr Neurol. 2008;39(1):6–11. https://doi.org/10.1016/j.pediatrneurol.2008.03.007.

    Article  PubMed  Google Scholar 

  103. Odegard SS, Engstrom M, Sand T, Stovner LJ, Zwart JA, Hagen K. Associations between sleep disturbance and primary headaches: the third Nord-Trondelag Health Study. J Headache Pain. 2010;11(3):197–206. https://doi.org/10.1007/s10194-010-0201-8.

    Article  PubMed  PubMed Central  Google Scholar 

  104. Johnson KG, Ziemba AM, Garb JL. Improvement in headaches with continuous positive airway pressure for obstructive sleep apnea: a retrospective analysis. Headache. 2013;53(2):333–43. https://doi.org/10.1111/j.1526-4610.2012.02251.x.

    Article  PubMed  Google Scholar 

  105. Barløse M, Lund N, Jensen R. Sleep in trigeminal autonomic cephalagias: a review. Cephalalgia. 2014;34(10):813–22. https://www.researchgate.net/publication/263777054.

    Article  Google Scholar 

  106. Kudrow L, Mac Ginty DJ, Phillips ER, Stevenson M. Sleep apnea in cluster headache. Cephalalgia. 1984;4(1):33–8. https://doi.org/10.1046/j.1468-2982.1984.0401033.x.

    Article  PubMed  Google Scholar 

  107. Graff-Radford SB, Newman A. Obstructive sleep apnea and cluster headache. Headache. 2004;44(6):607–10. https://doi.org/10.1111/j.1526-4610.2004.446010.x.

    Article  PubMed  Google Scholar 

  108. Bursztein C, Steinberg T, Sadeh A. Sleep, sleepiness, and behavior problems in children with headache. J Child Neurol. 2006;21(12):1012–9. https://www.researchgate.net/publication/6642269.

    Article  PubMed  Google Scholar 

  109. Carra MC, Bruni O, Huynh N. Topical review: sleep bruxism, headaches, and sleep-disordered breathing in children and adolescents. J Orofac Pain. 2012;26(4):267–76.

    PubMed  Google Scholar 

  110. Fernandes G, Franco-Michelone AL, Siqueira JT, Goncalves DA, Camparis CM. Parafunctional habits are associated cumulatively to painful temporomandibular disorders in adolescents. Braz Oral Res. 2016;30(1):0015. https://doi.org/10.1590/1807-3107BOR-2016.vol30.0015.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. Gary Demerjian .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Demerjian, G.G., Goel, P., Patel, M., Sims, A., Demerjian, RM., Barkhordarian, A. (2022). Dental Comorbidities and Risk Factors of Sleep-Disordered Breathing. In: Demerjian, G.G., Patel, M., Chiappelli, F., Barkhordarian, A. (eds) Dental Sleep Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-10646-0_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-10646-0_6

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-10645-3

  • Online ISBN: 978-3-031-10646-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics