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Intraductal Papillary Mucinous Neoplasm (IPMN)

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Imaging and Pathology of Pancreatic Neoplasms

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) are a group of exocrine mucin-producing tumors, diagnosed at a mean age of 60 years, with male prevalence.

Improvements in imaging techniques have led to an increasing incidental detection of IPMNs.

Age and clinical, laboratory, and imaging findings are accurate in stratifying these lesions, and imaging plays a pivot role in their management.

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References

  1. Kim YH, Saini S, Sahani D, et al. Imaging diagnosis of cystic pancreatic lesions: pseudocyst versus nonpseudocyst. Radiographics. 2005;25(3):671–85.

    Article  PubMed  Google Scholar 

  2. Manfredi R, Mehrabi S, Motton M, et al. MR imaging and MR cholangiopancreatography of multifocal intraductal papillary mucinous neoplasms of the side branches: MR pattern and its evolution. Radiol Med. 2008;113(3):414–28.

    Article  CAS  PubMed  Google Scholar 

  3. Berland LL, Silverman SG, Gore RM, et al. Managing incidental findings on abdominal CT: white paper of the ACR incidental findings committee. J Am Coll Radiol. 2010;7(10):754–73.

    Article  PubMed  Google Scholar 

  4. Zhang XM, Mitchell DG, Dohke M, et al. Pancreatic cysts: depiction on single-shot fast spin-echo MR images. Radiology. 2002;223(2):547–53.

    Article  PubMed  Google Scholar 

  5. Fernandez-del Castillo C, Targarona J, Thayer SP, et al. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003;138(4):427–34.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Lewin M, Hoeffel C, Azizi L, et al. Imaging of incidental cystic lesions of the pancreas. J Radiol. 2008;89(2):197–207.

    Article  CAS  PubMed  Google Scholar 

  7. Fukukura Y, Fujiyoshi F, Sasaki M, et al. Intraductal papillary mucinous tumors of the pancreas: thin-section helical CT findings. AJR Am J Roentgenol. 2000;174(2):441–7.

    Article  CAS  PubMed  Google Scholar 

  8. Manfredi R, Graziani R, Motton M, et al. Main pancreatic duct intraductal papillary mucinous neoplasms: accuracy of MR imaging in differentiation between benign and malignant tumors compared with histopathologic analysis. Radiology. 2009;253(1):106–15.

    Article  PubMed  Google Scholar 

  9. Procacci C, Megibow AJ, Carbognin G, et al. Intraductal papillary mucinous tumor of the pancreas: a pictorial essay. Radiographics. 1999;19(6):1447–63.

    Article  CAS  PubMed  Google Scholar 

  10. Ishida M, Egawa S, Aoki T, et al. Characteristic clinicopathological features of the types of intraductal papillary-mucinous neoplasms of the pancreas. Pancreas. 2007;35(4):348–52.

    Article  PubMed  Google Scholar 

  11. Schmidt CM, Yip-Schneider MT, Ralstin MC, et al. PGE(2) in pancreatic cyst fluid helps differentiate IPMN from MCN and predict IPMN dysplasia. J Gastrointest Surg. 2008;12(2):243–9.

    Article  PubMed  Google Scholar 

  12. Pitman MB, Genevay M, Yaeger K, et al. High-grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than “positive” cytology. Cancer Cytopathol. 2010;118(6):434–40.

    Article  PubMed  Google Scholar 

  13. Tanaka M, Fernandez-del Castillo C, Adsay V, et al. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology. 2012;12(3):183–97.

    Article  PubMed  Google Scholar 

  14. Adsay NV, Fukushima N, Furukawa T, et al. Intraductal neoplasms of the pancreas. In: Bosman FT, Carneiro F, Hruban RH, et al., editors. WHO classification of tumours of the digestive system. 4th ed. Lyon: IARC; 2010.

    Google Scholar 

  15. Luttges J, Zamboni G, Longnecker D, et al. The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncystic carcinoma and ductal adenocarcinoma. Am J Surg Pathol. 2001;25(7):942–8.

    Article  CAS  PubMed  Google Scholar 

  16. Chadwick B, Willmore-Payne C, Tripp S, et al. Histologic, immunohistochemical, and molecular classification of 52 IPMNs of the pancreas. Appl Immunohistochem Mol Morphol. 2009;17(1):31–9.

    Article  CAS  PubMed  Google Scholar 

  17. Mohri D, Asaoka Y, Ijichi H, et al. Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression. J Gastroenterol. 2012;47(2):203–13.

    Article  CAS  PubMed  Google Scholar 

  18. Hruban RH, Pitman MB, Klimstra DS, et al. Tumors of the pancreas. In: American registry of pathology in collaboration with the armed forces, vol. XVIII. Institute of Pathology, Washington, DC; 2007. p. 422. http://www.worldcat.org/title/tumors-of-the-pancreas/oclc/143399484.

    Google Scholar 

  19. Zamboni G, Hirabayashi K, Castelli P, et al. Precancerous lesions of the pancreas. Best Pract Res Clin Gastroenterol. 2013;27(2):299–322.

    Article  PubMed  Google Scholar 

  20. Adsay NV. Intraductal papillary mucinous neoplasms of the pancreas: pathology and molecular genetics. J Gastrointest Surg. 2002;6(5):656–9.

    Article  PubMed  Google Scholar 

  21. Adsay NV. The “new kid on the block”: intraductal papillary mucinous neoplasms of the pancreas: current concepts and controversies. Surgery. 2003;133(5):459–63.

    Article  PubMed  Google Scholar 

  22. Adsay NV, Merati K, Basturk O, et al. Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms: delineation of an “intestinal” pathway of carcinogenesis in the pancreas. Am J Surg Pathol. 2004;28(7):839–48.

    Article  PubMed  Google Scholar 

  23. Furukawa T, Klöppel G, Volkan Adsay N, et al. Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study. Virchows Arch. 2005;447(5):794–9.

    Article  PubMed  Google Scholar 

  24. Mino-Kenudson M, Fernández-del Castillo C, Baba Y, et al. Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes. Gut. 2011;60(12):1712–20.

    Article  PubMed  Google Scholar 

  25. Sessa F, Solcia E, Capella C, et al. Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch. 1994;425(4):357–67.

    Article  CAS  PubMed  Google Scholar 

  26. Lim JH, Lee G, Oh YL. Radiologic spectrum of intraductal papillary mucinous tumor of the pancreas. Radiographics. 2001;21(2):323–37.

    Article  CAS  PubMed  Google Scholar 

  27. Pilleul F, Rochette A, Partensky C, et al. Preoperative evaluation of intraductal papillary mucinous tumors performed by pancreatic magnetic resonance imaging and correlated with surgical and histopathologic findings. J Magn Reson Imaging. 2005;21(3):237–44.

    Article  PubMed  Google Scholar 

  28. Procacci C, Graziani R, Bicego E, et al. Intraductal mucin-producing tumors of the pancreas: imaging findings. Radiology. 1996;198(1):249–57.

    Article  CAS  PubMed  Google Scholar 

  29. Campbell F, Azadeh B. Cystic neoplasms of the exocrine pancreas. Histopathology. 2008;52(5):539–51.

    Article  CAS  PubMed  Google Scholar 

  30. Adsay NV. Cystic neoplasia of the pancreas: pathology and biology. J Gastrointest Surg. 2008;12(3):401–4.

    Article  PubMed  Google Scholar 

  31. Perez-Johnston R, Narin O, Mino-Kenudson M, et al. Frequency and significance of calcification in IPMN. Pancreatology. 2013;13(1):43–7.

    Article  CAS  PubMed  Google Scholar 

  32. Kang MJ, Jang JY, Kim SJ, et al. Cyst growth rate predicts malignancy in patients with branch duct intraductal papillary mucinous neoplasms. Clin Gastroenterol Hepatol. 2011;9(1):87–93.

    Article  PubMed  Google Scholar 

  33. D’Onofrio M, Gallotti A, Pozzi Mucelli R. Imaging techniques in pancreatic tumors. Expert Rev Med Devices. 2010;7(2):257–73.

    Article  PubMed  Google Scholar 

  34. Martinez-Noguera A, D’Onofrio M. Ultrasonography of the pancreas. 1. Conventional imaging. Abdom Imaging. 2007;32(2):136–49.

    Article  CAS  PubMed  Google Scholar 

  35. Bennett GL, Hann LE. Pancreatic ultrasonography. Surg Clin North Am. 2001;81(2):259–81.

    Article  CAS  PubMed  Google Scholar 

  36. Hohl C, Schmidt T, Honnef D, et al. Ultrasonography of the pancreas. 2. Harmonic imaging. Abdom Imaging. 2007;32(2):150–60.

    Article  CAS  PubMed  Google Scholar 

  37. Piscaglia F, Nolsoe C, Dietrich CF, et al. The EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): update 2011 on non-hepatic applications. Ultraschall Med. 2012;33(1):33–59.

    Article  CAS  PubMed  Google Scholar 

  38. Kurihara N, Kawamoto H, Kobayashi Y, et al. Vascular patterns in nodules of intraductal papillary mucinous neoplasms depicted under contrast-enhanced ultrasonography are helpful for evaluating malignant potential. Eur J Radiol. 2012;81(1):66–70.

    Article  PubMed  Google Scholar 

  39. D’Onofrio M, Zamboni G, Malago R, et al. Pancreatic pathology. In: Quaia E, editor. Contrast media in ultrasonography. Berlin: Springer; 2005. p. 335–47.

    Chapter  Google Scholar 

  40. Itoh T, Hirooka Y, Itoh A, et al. Usefulness of contrast-enhanced transabdominal ultrasonography in the diagnosis of intraductal papillary mucinous tumors of the pancreas. Am J Gastroenterol. 2005;100(1):144–52.

    Article  PubMed  Google Scholar 

  41. Sahani DV, Sainani NI, Blake MA, et al. Prospective evaluation of reader performance on MDCT in characterization of cystic pancreatic lesions and prediction of cyst biologic aggressiveness. AJR Am J Roentgenol. 2011;197(1):W53–61.

    Article  PubMed  Google Scholar 

  42. Sainani NI, Saokar A, Deshpande V, et al. Comparative performance of MDCT and MRI with MR cholangiopancreatography in characterizing small pancreatic cysts. AJR Am J Roentgenol. 2009;193(3):722–31.

    Article  PubMed  Google Scholar 

  43. Shah AA, Sainani NI, Kambadakone AR, et al. Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma: radiologic-pathologic correlation. World J Gastroenterol. 2009;15(22):2739–47.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Kawamoto S, Lawler LP, Horton KM, et al. MDCT of intraductal papillary mucinous neoplasm of the pancreas: evaluation of features predictive of invasive carcinoma. AJR Am J Roentgenol. 2006;186(3):687–95.

    Article  PubMed  Google Scholar 

  45. Song SJ, Lee JM, Kim YJ, et al. Differentiation of intraductal papillary mucinous neoplasms from other pancreatic cystic masses: comparison of multirow-detector CT and MR imaging using ROC analysis. J Magn Reson Imaging. 2007;26(1):86–93.

    Article  PubMed  Google Scholar 

  46. Sahani DV, Kadavigere R, Blake M, et al. Intraductal papillary mucinous neoplasm of pancreas: multi-detector row CT with 2D curved reformations–correlation with MRCP. Radiology. 2006;238(2):560–9.

    Article  PubMed  Google Scholar 

  47. Sandrasegaran K, Lin C, Akisik FM, et al. State-of-the-art pancreatic MRI. AJR Am J Roentgenol. 2010;195(1):42–53.

    Article  PubMed  Google Scholar 

  48. Kim JH, Eun HW, Park HJ, et al. Diagnostic performance of MRI and EUS in the differentiation of benign from malignant pancreatic cyst and cyst communication with the main duct. Eur J Radiol. 2012;81(11):2927–35.

    Article  PubMed  Google Scholar 

  49. Lee HJ, Kim MJ, Choi JY, et al. Relative accuracy of CT and MRI in the differentiation of benign from malignant pancreatic cystic lesions. Clin Radiol. 2011;66(4):315–21.

    Article  PubMed  Google Scholar 

  50. Kartalis N, Lindholm TL, Aspelin P, et al. Diffusion-weighted magnetic resonance imaging of pancreas tumours. Eur Radiol. 2009;19(8):1981–90.

    Article  PubMed  Google Scholar 

  51. Pedrazzoli S, Sperti C, Pasquali C, et al. Comparison of international consensus guidelines versus 18-FDG PET in detecting malignancy of intraductal papillary mucinous neoplasms of the pancreas. Ann Surg. 2011;254(6):971–6.

    Article  PubMed  Google Scholar 

  52. Hong HS, Yun M, Cho A, et al. The utility of F-18 FDG PET/CT in the evaluation of pancreatic intraductal papillary mucinous neoplasm. Clin Nucl Med. 2010;35(10):776–9.

    Article  PubMed  Google Scholar 

  53. Takanami K, Hiraide T, Tsuda M, et al. Additional value of FDG PET/CT to contrast-enhanced CT in the differentiation between benign and malignant intraductal papillary mucinous neoplasms of the pancreas with mural nodules. Ann Nucl Med. 2011;25(7):501–10.

    Article  PubMed  Google Scholar 

  54. Tomimaru Y, Takeda Y, Tatsumi M, et al. Utility of 2-[18 F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas. Oncol Rep. 2010;24(3):613–20.

    PubMed  Google Scholar 

  55. Carlson SK, Johnson CD, Brandt KR, et al. Pancreatic cystic neoplasms: the role and sensitivity of needle aspiration and biopsy. Abdom Imaging. 1998;23(4):387–93.

    Article  CAS  PubMed  Google Scholar 

  56. Pais SA, Attasaranya S, Leblanc JK, et al. Role of endoscopic ultrasound in the diagnosis of intraductal papillary mucinous neoplasms: correlation with surgical histopathology. Clin Gastroenterol Hepatol. 2007;5(4):489–95.

    Article  PubMed  Google Scholar 

  57. Kubo H, Chijiiwa Y, Akahoshi K, et al. Intraductal papillary-mucinous tumors of the pancreas: differential diagnosis between benign and malignant tumors by endoscopic ultrasonography. Am J Gastroenterol. 2001;96(5):1429–34.

    Article  CAS  PubMed  Google Scholar 

  58. Nakagawa A, Yamaguchi T, Ohtsuka M, et al. Usefulness of multidetector computed tomography for detecting protruding lesions in intraductal papillary mucinous neoplasm of the pancreas in comparison with single-detector computed tomography and endoscopic ultrasonography. Pancreas. 2009;38(2):131–6.

    Article  PubMed  Google Scholar 

  59. Hong SK, Loren DE, Rogart JN, et al. Targeted cyst wall puncture and aspiration during EUS-FNA increases the diagnostic yield of premalignant and malignant pancreatic cysts. Gastrointest Endosc. 2012;75(4):775–82.

    Article  PubMed  Google Scholar 

  60. Rogart JN, Loren DE, Singu BS, et al. Cyst wall puncture and aspiration during EUS-guided fine needle aspiration may increase the diagnostic yield of mucinous cysts of the pancreas. J Clin Gastroenterol. 2011;45(2):164–9.

    Article  PubMed  Google Scholar 

  61. Buscarini E, Pezzilli R, Cannizzaro R, et al. Italian consensus guidelines for the diagnostic work-up and follow-up of cystic pancreatic neoplasms. Dig Liver Dis. 2014;46(6):479–93.

    Article  PubMed  Google Scholar 

  62. Yamaguchi K, Ohuchida J, Ohtsuka T, et al. Intraductal papillary-mucinous tumor of the pancreas concomitant with ductal carcinoma of the pancreas. Pancreatology. 2002;2(5):484–90.

    Article  PubMed  Google Scholar 

  63. Yamaguchi K, Kanemitsu S, Hatori T, et al. Pancreatic ductal adenocarcinoma derived from IPMN and pancreatic ductal adenocarcinoma concomitant with IPMN. Pancreas. 2011;40(4):571–80.

    Article  PubMed  Google Scholar 

  64. Yamaguchi K, Chijiiwa K, Shimizu S, et al. Intraductal papillary neoplasm of the pancreas: a clinical review of 13 benign and four malignant tumours. Eur J Surg. 1999;165(3):223–9.

    Article  CAS  PubMed  Google Scholar 

  65. Calculli L, Pezzilli R, Brindisi C, et al. Pancreatic and extrapancreatic lesions in patients with intraductal papillary mucinous neoplasms of the pancreas: a single-centre experience. Radiol Med. 2010;115(3):442–52.

    Article  CAS  PubMed  Google Scholar 

  66. Lee SY, Choi DW, Jang KT, et al. High expression of intestinal-type mucin (MUC2) in intraductal papillary mucinous neoplasms coexisting with extrapancreatic gastrointestinal cancers. Pancreas. 2006;32(2):186–9.

    Article  CAS  PubMed  Google Scholar 

  67. Pugliese L, Del Chiaro M, D’Haese J, et al. Extrapancreatic neoplasms in patients with IPMN: is there an increased risk? JOP. 2013;14(5 Suppl):590.

    Google Scholar 

  68. Yamada Y, Mori H, Hijiya N, et al. Intraductal papillary mucinous neoplasms of the pancreas complicated with intraductal hemorrhage, perforation, and fistula formation: CT and MR imaging findings with pathologic correlation. Abdom Imaging. 2012;37(1):100–9.

    Article  PubMed  Google Scholar 

  69. Kurihara K, Nagai H, Kasahara K, et al. Biliopancreatic fistula associated with intraductal papillary-mucinous pancreatic cancer: institutional experience and review of the literature. Hepato-Gastroenterology. 2000;47(34):1164–7.

    CAS  PubMed  Google Scholar 

  70. Koizumi M, Sata N, Yoshizawa K, et al. Post-ERCP pancreatogastric fistula associated with an intraductal papillary-mucinous neoplasm of the pancreas–a case report and literature review. World J Surg Oncol. 2005;3:70.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Motosugi U, Yamaguchi H, Furukawa T, et al. Imaging studies of intraductal tubulopapillary neoplasms of the pancreas: 2-tone-duct sign and cork-of-wine-bottle sign as indicators of intraductal tumor growth. J Comput Assist Tomogr. 2012;36(6):710–7.

    Article  PubMed  Google Scholar 

  72. Konigsrainer I, Glatzle J, Kloppel G, et al. Intraductal and cystic tubulopapillary adenocarcinoma of the pancreas-a possible variant of intraductal tubular carcinoma. Pancreas. 2008;36(1):92–5.

    Article  PubMed  Google Scholar 

  73. Tajiri T, Tate G, Inagaki T, et al. Intraductal tubular neoplasms of the pancreas: histogenesis and differentiation. Pancreas. 2005;30(2):115–21.

    Article  PubMed  Google Scholar 

  74. Tajiri T, Tate G, Kunimura T, et al. Histologic and immunohistochemical comparison of intraductal tubular carcinoma, intraductal papillary-mucinous carcinoma, and ductal adenocarcinoma of the pancreas. Pancreas. 2004;29(2):116–22.

    Article  PubMed  Google Scholar 

  75. Kalaitzakis E, Braden B, Trivedi P, et al. Intraductal papillary mucinous neoplasm in chronic calcifying pancreatitis: egg or hen? World J Gastroenterol. 2009;15(10):1273–5.

    Article  PubMed  PubMed Central  Google Scholar 

  76. Inan N, Arslan A, Akansel G, et al. Diffusion-weighted imaging in the differential diagnosis of cystic lesions of the pancreas. AJR Am J Roentgenol. 2008;191(4):1115–21.

    Article  PubMed  Google Scholar 

  77. Koito K, Namieno T, Ichimura T, et al. Mucin-producing pancreatic tumors: comparison of MR cholangiopancreatography with endoscopic retrograde cholangiopancreatography. Radiology. 1998;208(1):231–7.

    Article  CAS  PubMed  Google Scholar 

  78. Kim JH, Hong SS, Kim YJ, et al. Intraductal papillary mucinous neoplasm of the pancreas: differentiate from chronic pancreatitis by MR imaging. Eur J Radiol. 2012;81(4):671–6.

    Article  PubMed  Google Scholar 

  79. Zhang XM, Shi H, Parker L, et al. Suspected early or mild chronic pancreatitis: enhancement patterns on gadolinium chelate dynamic MRI. J Magn Reson Imaging. 2003;17(1):86–94.

    Article  CAS  PubMed  Google Scholar 

  80. Sahani DV, Kadavigere R, Saokar A, et al. Cystic pancreatic lesions: a simple imaging-based classification system for guiding management. Radiographics. 2005;25(6):1471–84.

    Article  PubMed  Google Scholar 

  81. Warshaw AL, Compton CC, Lewandrowski K, et al. Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg. 1990;212(4):432–43.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  82. Kim SY, Lee JM, Kim SH, et al. Macrocystic neoplasms of the pancreas: CT differentiation of serous oligocystic adenoma from mucinous cystadenoma and intraductal papillary mucinous tumor. AJR Am J Roentgenol. 2006;187(5):1192–8.

    Article  PubMed  Google Scholar 

  83. Attasaranya S, Pais S, LeBlanc J, et al. Endoscopic ultrasound-guided fine needle aspiration and cyst fluid analysis for pancreatic cysts. JOP. 2007;8(5):553–63.

    PubMed  Google Scholar 

  84. Repak R, Rejchrt S, Bartova J, et al. Endoscopic ultrasonography (EUS) and EUS-guided fine-needle aspiration with cyst fluid analysis in pancreatic cystic neoplasms. Hepato-Gastroenterology. 2009;56(91–92):629–35.

    PubMed  Google Scholar 

  85. Albores-Saavedra J. Acinar cystadenoma of the pancreas: a previously undescribed tumor. Ann Diagn Pathol. 2002;6(2):113–5.

    Article  PubMed  Google Scholar 

  86. Zamboni G, Terris B, Scarpa A, et al. Acinar cell cystadenoma of the pancreas: a new entity? Am J Surg Pathol. 2002;26(6):698–704.

    Article  PubMed  Google Scholar 

  87. Gumus M, Ugras S, Algin O, et al. Acinar cell cystadenoma (acinar cystic transformation) of the pancreas: the radiologic-pathologic features. Korean J Radiol. 2011;12(1):129–34.

    Article  PubMed  PubMed Central  Google Scholar 

  88. Khor TS, Badizadegan K, Ferrone C, et al. Acinar cystadenoma of the pancreas: a clinicopathologic study of 10 cases including multilocular lesions with mural nodules. Am J Surg Pathol. 2012;36(11):1579–91.

    Article  PubMed  Google Scholar 

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Morana, G. et al. (2022). Intraductal Papillary Mucinous Neoplasm (IPMN). In: D'Onofrio, M., Capelli, P., Pederzoli, P. (eds) Imaging and Pathology of Pancreatic Neoplasms. Springer, Cham. https://doi.org/10.1007/978-3-031-09831-4_5

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