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Colorectal Liver Metastasis

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  • © 2022

Overview

  • Covers recent developments in molecular biology and its impact for diagnosing and treating colorectal cancer

  • Provides a comprehensive overview of the latest surveillance strategies

  • Features instructional guidance on how to perform a two stage hepatectomy

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Table of contents (59 chapters)

  1. Introduction

  2. Surgery

Keywords

About this book

This book provides a practically applicable guide to the management of liver metastases in cases of colorectal cancer. It features detailed reviews of the latest diagnostic and therapeutic options. Instruction on how to appropriately apply surgical techniques including two stage hepatectomy as well as both laprascopic and open resection in a variety of scenarios is covered. The use of systemic therapies involving oxaliplatin, immunotherapy and infusional therapy are also described along with a range of surveillance strategies. 

Vauthey and Adam Colorectal Liver Metastasis comprehensively covers the latest advances in how to successfully diagnose and treat colorectal liver metastases and is an indispensable resource for all trainee and practicing medical professionals who encounter these patients within their clinical practice.    



Editors and Affiliations

  • Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA

    Jean-Nicolas Vauthey

  • Hepato-Biliary-Pancreatic Surgery Division Department of Surgery, Graduate School of Medicine The University of Tokyo, Tokyo, Japan

    Yoshikuni Kawaguchi

  • AP-HP Hôpital Paul Brousse Centre Hépato-Biliaire Research Team “Chronothérapie, Cancers et Transplantation” Université Paris-Saclay, Villejuif, France

    René Adam

About the editors

Dr. Jean-Nicolas Vauthey is Chief of the Hepato-Pancreato-Biliary Section in the Department of Surgical Oncology at The University of Texas MD Anderson Cancer Center and the Dallas Fort Worth Living Legend in Clinical Cancer Research Chair in Houston, USA. Dr. Vauthey co-authored more than 600 publications in peer-reviewed journals (h-index, 107) and more than 100 reviews and book chapters in major textbooks. Dr. Vauthey’s clinical research focuses on methods to measure and to improve outcome after hepatic resection for hepatobiliary malignancies. Dr. Vauthey proposed a standardized method for calculating the volume of the anticipated liver remnant prior to liver surgery. Dr. Vauthey has evaluated the use of preoperative chemotherapy in the multidisciplinary treatment of patients with hepatic colorectal metastases. He has pioneered the use of 2-stage hepatectomy for patients with advanced metastatic colorectal carcinoma to liver. Dr. Vauthey’s most recent work has focused on somatic mutations, circulating tumor DNA and their role in defining response, treatment, surveillance and prognosis after resection of colorectal liver metastases.

Dr. Yoshikuni Kawaguchi is Deputy Chief (Inpatient Care) of Hepato-Biliary-Pancreatic Surgery Division in the Department of Surgery at The University of Tokyo. Dr. Kawaguchi co-authored more than 130 publications in peer-reviewed journals (h-index, 25). Dr. Kawaguchi’s interest in clinical research is to improve short- and long-term outcomes of patients undergoing surgery for hepato-biliary-pancreatic diseases. Dr. Kawaguchi proposed a novel 3-level classification system for open and minimally-invasive liver resection, which is associated with liver resection complexity and postoperative complications. Dr. Kawaguchi has recently worked with Dr. Vauthey to improve the understanding of multiple somatic mutations of colorectal liver metastases for clinical practices including accurate prognostication after resection and recurrence risk-adjusted surveillance algorithm.




Professor René Adam is president of the Medical Board of the Paul Brousse Hospital, Villejuif, France and head of the Oncological Surgery Unit of the Hepato Biliary Center. Since 1994, he has held the position of professor of surgery at the Faculty of Medicine Kremlin Bicêtre at Paris South University, Paris. Professor Adam’s main fields of activity and research are surgery of the liver, biliary tract and pancreas, and hepatic transplantation. He is particularly involved in the treatment of hepatocellular carcinoma and of liver metastases. 

Bibliographic Information

  • Book Title: Colorectal Liver Metastasis

  • Editors: Jean-Nicolas Vauthey, Yoshikuni Kawaguchi, René Adam

  • DOI: https://doi.org/10.1007/978-3-031-09323-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-09322-7Published: 25 November 2022

  • Softcover ISBN: 978-3-031-09325-8Published: 25 November 2023

  • eBook ISBN: 978-3-031-09323-4Published: 24 November 2022

  • Edition Number: 1

  • Number of Pages: XXIV, 569

  • Number of Illustrations: 31 b/w illustrations, 276 illustrations in colour

  • Topics: Surgical Oncology, Oncology

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