Skip to main content
SpringerLink
Log in

Dermal Absorption and Decontamination

A Comprehensive Guide

  • Book
  • © 2022

Overview

Editors:
  1. Aileen M. Feschuk

    1. Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Rebecca M. Law

    1. School of Pharmacy, Memorial University of Newfoundland, St. John's, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Howard I. Maibach

    1. Department of Dermatology, University of California San Francisco, San Francisco, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • A comprehensive volume dedicated to dermal absorption and decontamination
  • Provides an up-to-date systemic review of each important dermal absorption and/or decontamination
  • Written primarily for dermatologists

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Skin Decontamination with Water: Evidence from In Vivo Human Studies

    • Nadia Kashetsky, Rebecca M. Law, Howard I. Maibach
    Pages 1-24

  3. Toward a Harmonized Protocol for Quantifying In Vitro Human Skin Decontamination Efficacy

    • Thaibinh Tran, Howard I. Maibach
    Pages 25-37

  4. In Vitro Human Skin Decontamination with Water: Chemical Warfare Agents or Simulants

    • Chavy Chiang, Nadia Kashetsky, Aileen M. Feschuk, Anuk Burli, Rebecca M. Law, Howard I. Maibach
    Pages 39-58

  5. In Vitro Human Skin Decontamination with Water: Occupational Contaminants

    • Chavy Chiang, Nadia Kashetsky, Aileen M. Feschuk, Anuk Burli, Rebecca M. Law, Howard I. Maibach
    Pages 59-81

  6. Skin Decontamination with Water: Evidence from In Vivo Animal Models

    • Anuk Burli, Nadia Kashetsky, Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach
    Pages 83-100

  7. Skin Decontamination with Water: Evidence from In Vitro Animal Models

    • Maxwell Green, Nadia Kashetsky, Aileen M. Feschuk, Howard I. Maibach
    Pages 101-114

  8. Dermal Decontamination with Readily Available Dry Products

    • Saisha Nandamuri, Aileen M. Feschuk, Howard I. Maibach
    Pages 115-132

  9. A Review of Reactive Skin Decontamination Lotion Efficacy

    • Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach
    Pages 133-145

  10. Aqueous Suspensions of Fuller’s Earth Potentiate the Adsorption Capacities of Paraoxon and Improve Skin Decontamination Properties

    • Alix Danoy, Kardelen Durmaz, Margaux Paoletti, Laetitia Vachez, Annick Roul, Jérôme Sohier et al.
    Pages 147-167

  11. Development of a Next Generation Military Skin Decontaminant: Initial Efficacy Studies of Zirconium Hydroxide

    • Hazem Matar, Shawn Stevenson, Robert P. Chilcott, Kevin Morrissey
    Pages 169-181

  12. Findings from the PHOENIX Project: ‘Protocols for Hair and the Optimisation of Existing and Novel Decontamination Interventions Through Experimentation’

    • Tim Marczylo, Tom James, Richard Amlot, Samuel Collins
    Pages 183-202

  13. Twenty Clinically Pertinent Factors/Observations for Percutaneous Absorption in Humans

    • Rebecca M. Law, Mai A. Ngo, Howard I. Maibach
    Pages 203-221

  14. Lateral Spread and Percutaneous Penetration: An Overview

    • Rebecca M. Law, Howard I. Maibach
    Pages 223-233

  15. Regional Variation in Percutaneous Absorption: Evidence from In Vitro Human Models

    • Aileen M. Feschuk, Nadia Kashetsky, Chavy Chiang, Anuk Burli, Halie Burdick, Howard I. Maibach
    Pages 235-257

  16. Experimental Variability in TEWL Data

    • Reva P. Peer, Anuk Burli, Howard I. Maibach
    Pages 259-294

  17. Relationships Between Skin of Color and the TEWL Barrier

    • Reva P. Peer, Anuk Burli, Howard I. Maibach
    Pages 295-314

  18. Zinc Oxide Nanoparticles In Vitro Human Skin Decontamination

    • Yachao Cao, Xiaoying Hui, Akram Elmahdy, Hanjiang Zhu, Howard I. Maibach
    Pages 315-334

  19. Back Matter

    Pages 335-339
    Download chapter PDF
Back to top

Keywords

About this book

This book is a comprehensive volume dedicated to dermal absorption and decontamination. Given risks including chemical warfare and accidents with toxic industrial chemicals, studies involving dermal absorption and decontamination are of the utmost importance. Each chapter consists of a systematic review on an important dermal absorption and/or decontamination topic. Chapters address key issues such as the general acceptance of water/ soap and water as the gold standard of dermal decontamination despite the fact that it commonly provides incomplete decontamination and may even result in a “wash-in effect” (an increased penetration of contaminant). Decontamination with other substances (e.g. RSDL) is explored, and factors that affect dermal penetration (e.g. anatomical variation) are summarized. All systematic reviews are comprehensive and up-to-date. 


Dermal Absorption and Decontamination will be useful for many fields and disciplines. Firstly,information on dermal decontamination may be used by governments for military and national defense purposes in the event of chemical warfare. Additionally, this information would be of use to many production companies, whose employees are at risk of an accident with toxic industrial chemicals. Topics covered in the book will also be of use to pharmaceutical companies, especially those exploring transdermal delivery of drugs and is of great relevance to those in the medical field, particularly dermatologists. 

Editors and Affiliations

  • Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada

    Aileen M. Feschuk

  • School of Pharmacy, Memorial University of Newfoundland, St. John's, Canada

    Rebecca M. Law

  • Department of Dermatology, University of California San Francisco, San Francisco, USA

    Howard I. Maibach

About the editors

Aileen M Feschuk Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada


Rebecca M Law, PharmD
School of Pharmacy, Memorial University of Newfoundland
Faculty of Medicine, Memorial University of NewfoundlandSt. John’s, NL, Canada


Howard I Maibach, MD
Department of Dermatology, University of California San Francisco, San Francisco, CA, USA


Bibliographic Information

  • Book Title: Dermal Absorption and Decontamination

  • Book Subtitle: A Comprehensive Guide

  • Editors: Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach

  • DOI: https://doi.org/10.1007/978-3-031-09222-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-09221-3Published: 06 October 2022

  • Softcover ISBN: 978-3-031-09224-4Published: 07 October 2023

  • eBook ISBN: 978-3-031-09222-0Published: 05 October 2022

  • Edition Number: 1

  • Number of Pages: VIII, 339

  • Number of Illustrations: 12 b/w illustrations, 21 illustrations in colour

  • Topics: Dermatology

Publish with us

Policies and ethics

Back to top

Search

Navigation