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Hierarchical and Global Modality Interaction for Brain Tumor Segmentation

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Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2021)

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Abstract

Multi-modality brain tumor segmentation is vital for the treatment of gliomas, which aims to predict the regions of the necrosis, edema and tumor core on multi-modality magnetic resonance images (MRIs). However, it is a challenging task due to the complex appearance and diversity shapes of tumors. Considering that multi modality of MRIs contain rich biological properties of the tumors, we propose a novel multi-modality tumor segmentation network for segmenting the brain tumor based on fusing the complementary information and global semantic dependency information upon the multi-modality imaging data. Specifically, we propose a hierarchical modality interaction block to build the internal relationship between complementary modality pair, and then enhance the complementary information between the them by using the channel and spatial co-attention. To capture the long-dependency relationship of cross-modality information, we propose a global modality interaction transformer block to build the global semantic interaction between the multi-modality local features. The global modality interaction Transformer block makes up for CNN’s poor perception of global semantic dependency information across modes. We evaluate our method on the validation set of multi-modality brain tumor segmentation challenge 2021 (BraTs2021). The proposed multi-modality brain tumor segmentation network achieves 0.8518, 0.8808 and 0.926 Dice score for the ET, CT and WT.

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Acknowledgment

This work was supported by the National Key R&D Program of China under Grant 2020AAA0105701, the Key-Area Research and Development Program of Guangdong Province(2019B010110001), the National Science Foundation of China (Grant Nos. 61936007, 61876140, 61806167 and U1801265), and the research funds for interdisciplinary subject, NWPU.

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Correspondence to Dingwen Zhang .

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Yang, Y., Wei, S., Zhang, D., Yan, Q., Zhao, S., Han, J. (2022). Hierarchical and Global Modality Interaction for Brain Tumor Segmentation. In: Crimi, A., Bakas, S. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2021. Lecture Notes in Computer Science, vol 12962. Springer, Cham. https://doi.org/10.1007/978-3-031-08999-2_38

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  • DOI: https://doi.org/10.1007/978-3-031-08999-2_38

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-031-08999-2

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