Overview
- Describes the latest advancements in the area of cellular signaling mechanisms in the heart and blood vessels
- Helps investigators in the field towards achieving effective drug therapies for CVDs
- Covers the two major categories of CVDs: vascular and myocardial signaling
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Table of contents (18 chapters)
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Cardiac Signaling
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Vascular Signaling
Keywords
- cellular signaling in vascular health and disease
- signaling mechanisms in heart diseases
- cardiomyocyte signaling in ischemia and reperfusion damage
- myocardial fibroblast signaling in heart diseases
- protein kinases in cardiomyocytes
- phospholipase signaling in heart disease
- oxidant lipid signaling vascular diseases
- endothelial nitric oxide signaling
- vascular cellular signaling in atherosclerosis
- signaling in myocardial arrhthmia
- vascular cytoskeletal signaling
- blood vessel disorders and diseases
- myocardium and blood vessls
About this book
This book assembles the most important discoveries made by leaders on the cellular signaling mechanisms operating behind the development and progression of life-threatening CVDs. It is an extremely useful resource for the investigators in the field of CVDs, and opens the discussion for further discovery of efficient management and effective treatment of the CVDs.
Editors and Affiliations
About the editors
Dr. Hund is a Professor of Biomedical Engineering andInternal Medicine at The Ohio State University and a Fellow of the American Heart Association. He also serves as Director and the William D. And Jacquelyn L. Wells Chair at the Dorothy M. Davis Heart and Lung Research Institute in the OSU Wexner Medical Center. Research in the Hund lab has defined novel molecular pathways for local control of cardiac ion channel activity with important implications for human cardiac arrhythmia and heart failure. His group has developed novel computational models and tools to study cardiac electrophysiology and arrhythmia that are routinely used by labs around the world. His approach is distinguished by a highly interdisciplinary style combining state-of-the-art computational and experimental techniques. He has published >100 peer-reviewed articles and although he has contributed several book chapters in the past, Cardiovascular Signaling in Health and Disease represents his first volume as co-editor. In his roleas Director, Dr. Hund oversees strategic planning and operations for one of the largest interdisciplinary institutes in the country with >700 faculty, staff, and trainees dedicated to the integrated study of heart and lung disease. In addition to his research and leadership achievements, Dr. Hund has been recognized for his dedication to promoting undergraduate and graduate education through curriculum development, didactic teaching and mentoring. He has mentored dozens of students, postdocs and fellows, the large majority of whom go on to successful scientific careers in industry or academia. Pre- and postdoctoral trainees in the Hund lab have been very successful in securing independent fellowship awards, including NIH K99/R00 “Pathway to Independence” Awards, NIH Ruth L. Kirchstein National Research Service Awards, and Pre- and Postdoctoral Fellowship Awards from the American Heart Association. Dr. Hund has also regularly taught several courses in the Departmentof Biomedical Engineering, including a popular graduate course on Excitable Cell Engineering. Before joining Ohio State in July 2011, Dr. Hund was an Assistant Professor of Internal Medicine and Biomedical Engineering at University of Iowa. He received his B.S.E. in Biomedical Engineering from Duke University and his M.S. and Ph.D. in Biomedical Engineering from Case Western Reserve University, followed by postdoctoral training at Washington University School of Medicine in St. Louis.
Bibliographic Information
Book Title: Cardiovascular Signaling in Health and Disease
Editors: Narasimham L. Parinandi, Thomas J. Hund
DOI: https://doi.org/10.1007/978-3-031-08309-9
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-031-08308-2Published: 21 September 2022
Softcover ISBN: 978-3-031-08311-2Published: 22 September 2023
eBook ISBN: 978-3-031-08309-9Published: 21 September 2022
Edition Number: 1
Number of Pages: XVIII, 527
Number of Illustrations: 24 b/w illustrations, 59 illustrations in colour
Topics: Biomechanics, Biomedical Engineering and Bioengineering, Physiology, Cardiac Imaging, Biochemistry, general, Medical Biochemistry