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Intra-arterial Chemotherapy for Retinoblastoma: A Team Effort

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Global Perspectives in Ocular Oncology

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Abstract

Intra-arterial chemotherapy (IAC) for retinoblastoma treatment, also called superselective ophthalmic artery chemotherapy or chemosurgery, is a technique that allows a localized drug delivery to the ocular target. Currently, it is restricted to retinoblastoma (RB), permitting primary and salvage treatment for moderate and advanced RB (stage B to selected E), especially in eyes that would otherwise undergo enucleation. Intra-arterial chemosurgery conserves many eyes with retinoblastoma avoiding at the same time the risks of systemic chemotherapy and radiotherapy.

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Author information

Authors and Affiliations

  1. Department of Medicine, Surgery and Neurosciences, Ophthalmology Unit, Oncology Service, Siena, Italy

    Theodora Hadjistilianou

  2. Clinical Department of Neurological and Human Movement Sciences, Interventional Neuroradiology Unit, Hospital S. Maria alle Scotte, Siena, Italy

    Sandra Bracco

  3. Department Medicine, Surgery and Neurosciences, Ophthalmology Unit, Siena, Italy

    Matteo Barchitta

  4. Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy

    Eugenio Bertelli

Authors
  1. Theodora Hadjistilianou
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  2. Sandra Bracco
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  3. Matteo Barchitta
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  4. Eugenio Bertelli
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Corresponding author

Correspondence to Theodora Hadjistilianou .

Editor information

Editors and Affiliations

  1. Ocular Oncology Service Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

    Bhavna V. Chawla

  2. Retina Service Massachusetts Eye and Ear Harvard Medical School, Boston, MA, USA

    Mary E. Aronow

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Hadjistilianou, T., Bracco, S., Barchitta, M., Bertelli, E. (2022). Intra-arterial Chemotherapy for Retinoblastoma: A Team Effort. In: Chawla, B.V., Aronow, M.E. (eds) Global Perspectives in Ocular Oncology. Springer, Cham. https://doi.org/10.1007/978-3-031-08250-4_7

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  • DOI: https://doi.org/10.1007/978-3-031-08250-4_7

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  • Online ISBN: 978-3-031-08250-4

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