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Polypharmacology

Principles and Methodologies

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  • © 2022

Overview

  • Provides comprehensive, in-depth mechanisms behind the knowledge and methodology of Polypharmacology
  • Emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTSD)” pharmacology
  • Contains a wide collection of the state-of-the-art Polypharmacology technologies

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About this book

There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This book aims to meet the needs making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of this book targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy.

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Keywords

Table of contents (21 chapters)

Authors and Affiliations

  • Department of Pharmacology, Harbin Medical University, Harbin, China

    Zhiguo Wang, Baofeng Yang

About the authors

 Zhiguo Wang PhD received his PhD in cardiovascular pharmacology from McGill University, Canada. He is presently the Director of the Division of Drug Discovery, Meditech Institute of Research and Advance (USA) and a Distinguished Professor in the Department of Pharmacology, Harbin Medical University. He is an author of over 150 research articles in prestigious scientific journals and of 6 monographs and 15 book chapters with renowned scientific publishers. His research interests cover cardiovascular disease and pharmacology, molecular pharmacology, epigenetic polypharmacology. His research group is one of the earliest investigators who proposed “one drug, multiple targets” polypharmacology concept and provided the experimental evidence in support of the epigenetic polypharmacology.

Bibliographic Information

  • Book Title: Polypharmacology

  • Book Subtitle: Principles and Methodologies

  • Authors: Zhiguo Wang, Baofeng Yang

  • DOI: https://doi.org/10.1007/978-3-031-04998-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-04997-2Published: 02 August 2022

  • Softcover ISBN: 978-3-031-05000-8Published: 03 August 2023

  • eBook ISBN: 978-3-031-04998-9Published: 01 August 2022

  • Edition Number: 1

  • Number of Pages: XXV, 856

  • Number of Illustrations: 3 b/w illustrations, 9 illustrations in colour

  • Topics: Pharmacology/Toxicology, Pharmaceutical Sciences/Technology, Biotechnology, Neurosciences

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