Skip to main content
SpringerLink
Log in

Spectroscopy Technologies for Biological Samples Throughout History

  • Conference paper
  • First Online:
Proceedings of the 7th Brazilian Technology Symposium (BTSym’21) (BTSym 2021)

Part of the book series: Smart Innovation, Systems and Technologies ((SIST,volume 207))

Included in the following conference series:

  • 474 Accesses

Abstract

The evolution of biotechnological processes has been facing a huge demand for developing low-cost, non-invasive, and highly accurate platforms for biological samples. Thus, biospectroscopy has emerged to meet this demand. Important applications arise from biomedical spectroscopy in the areas of identification of proteins, microorganisms, and others. Biological samples such as saliva, serum, blood, and urine are composed of proteins and metabolic that can be used to identify different diseases. Compounds present in biological fluids can be an excellent source of identification of viruses, bacterial infection, cancer, metabolic diseases, among others. In the last few years, the biospectroscopy has been introduced in biological process, acting in the band from 1800 to 900 cm−1, also known as “biofingerprint” (biological fingerprint), has a high density of information about important biomolecules, and is used to identify different nucleic acids and other biological constituents. In this review, we describe the main spectroscopy techniques and how they work. It is also presented works about the potential application of spectroscopic techniques for different biological samples, focusing on ultraviolet-visible, infrared (NIR and MIR), fluorescence, and Raman spectroscopy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Martins, R.A., Silva, C.C.: As pesquisas de Newton sobre a luz: Uma visão histórica. Revista Brasileira de Ensino de Física 37(4), 1–32 (2015)

    Article  Google Scholar 

  2. Tkachenko, N.V.: Optical Spectroscopy Methods and Instrumentations, 1st edn. Elsevier, Oxford (2006)

    Google Scholar 

  3. Skoog, D.A., Holler, F.J., Crouch, S.R.: Principles of Instrumental Analysis, 7th edn. Cengage, Boston (2007)

    Google Scholar 

  4. Meidyawati, R., Adiyasa, J., Djauharie, N.: Phosphate concentration in unstimulated saliva of patients with type 2 Diabetes Mellitus. J. Int. Dental Med. Res. 12(3), 1182–1188 (2019)

    Google Scholar 

  5. Heidari, A., Gobato, R.: Human cancer cells and tissues with the passage of time under synchrotron radiation. Parana J. Sci. Educ. 4(6), 18–33 (2018)

    Google Scholar 

  6. Horiba (2021), http://www.horiba.com. Accessed 01 Sep 2021

  7. Lakowicz, J.R.: Principles of Fluorescence Spectroscopy, 2nd edn. Springer, New York (1999)

    Book  Google Scholar 

  8. Santos, M.C.D., Monteiro, J.D., Araújo, J.M.G., Lima, K.M.G.: Molecular fluorescence spectroscopy with multi-way analysis techniques detects spectral variations distinguishing uninfected serum versus dengue or chikungunya viral infected samples. Nature 10(13758), 1–13 (2020)

    Google Scholar 

  9. Maurice, J., Lett, A.M., Skinner, C., Lim, A., Richardson, M., Thomas, A.P.: Transcutaneous fuorescence spectroscopy as a tool for non-invasive monitoring of gut function: first clinical experiences. Nature 10(16169), 1–13 (2020)

    Google Scholar 

  10. Stuart, H.B.: Infrared Spectroscopy: Fundamentals and Applications: Analytical Techniques in the Sciences.1nd edn. John Wiley & Sons Ltd, England (2004)

    Google Scholar 

  11. Rodrigues, R.P.C.B., Aguiar, E.M.G., Cardoso-Sousa, L., Caixeta, D.C., Guedes, C.C.F.V., Siqueira, W.L.: Differential molecular signature of human saliva using ATR-FTIR spectroscopy for chronic kidney disease diagnosis. Braz. Dent. J. 30(5), 437–445 (2019)

    Article  Google Scholar 

  12. Santos, M.C.D., Nascimentos, Y.M., Monteiro, J.D., Alves, B.E.B., Melo, M.F., Paive, A.A.P.: ATR-FTIR spectroscopy with chemometric algorithms of multivariate classification in the discrimination between healthy vs. dengue vs. chikungunya vs. zika clinical samples. Analytical Methods, 10(1280), 1–23 (2018)

    Google Scholar 

  13. Ferraro, J.R., Nakamoto, K.: Introductory Raman Spectroscopy: Academic Press, 2nd edn. Elsevier Science, California, USA (1994)

    Google Scholar 

  14. Stavelley, L.A.K.: The Chracterization of chemical purity organic compounds. 1nd edn. Pure and Applied Chemistry, Great Britain (1971)

    Google Scholar 

  15. Parachalil, D.R., Bruno, C., Bonnier, F., Blasco, H., Chourpa, I., McIntyre, J.: Raman Spectroscopic screening of high and low molecular weight fractions of human serum Analyst. Royal Soc. Chem. 144(7), 4295–4311 (2019)

    Google Scholar 

  16. Zhu, W., Wen, B.Y., Jie, L.J., Tian, X.D., Yang, Z.L., Radjenovic, P.M.: Rapid and low-cost quantitative detection of creatinine in human urine with a portable Raman spectrometer. Biosensors Biolectron. 154(112067), 1–8 (2020)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Fiberwork Optical Communication, Campinas, São Paulo, Brazil

    Talita Cristina Colomeu & Marina de Gea Neves

  2. iTech-Instituto de Inovações Fotônicas, Campinas, São Paulo, Brazil

    Euclides Lourenço Chuma

Authors
  1. Talita Cristina Colomeu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marina de Gea Neves
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Euclides Lourenço Chuma
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Talita Cristina Colomeu .

Editor information

Editors and Affiliations

  1. Faculty of Electrical and Computer Engineering, Unicamp, Campinas, São Paulo, Brazil

    Yuzo Iano

  2. Divisão de Engenharia Eletrônica, Instituto Tecnológico de Aeronáutica, São José dos Campos, São Paulo, Brazil

    Osamu Saotome

  3. Universidad Peruana de Ciencias Aplicadas, Santiago de Surco, Lima, Peru

    Guillermo Leopoldo Kemper Vásquez

  4. Pontifícia Universidade Católica de Campinas, Campinas, Brazil

    Claudia Cotrim Pezzuto

  5. Faculty of Electrical and Computer Engineering, Unicamp, Campinas, São Paulo, Brazil

    Rangel Arthur

  6. Universidade Estadual de Campinas, Hortolândia, Brazil

    Gabriel Gomes de Oliveira

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Colomeu, T.C., de Gea Neves, M., Chuma, E.L. (2023). Spectroscopy Technologies for Biological Samples Throughout History. In: Iano, Y., Saotome, O., Kemper Vásquez, G.L., Cotrim Pezzuto, C., Arthur, R., Gomes de Oliveira, G. (eds) Proceedings of the 7th Brazilian Technology Symposium (BTSym’21). BTSym 2021. Smart Innovation, Systems and Technologies, vol 207. Springer, Cham. https://doi.org/10.1007/978-3-031-04435-9_25

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-04435-9_25

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-04434-2

  • Online ISBN: 978-3-031-04435-9

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics

Search

Navigation