Abstract
Radiotherapy plays an integral role in the management of laryngeal cancers of all stages. Hypofractionated radiotherapy offers excellent results for early-stage squamous cell carcinomas of the glottic larynx. Definitive chemoradiotherapy is a standard of care for advanced larynx cancers that are amenable to organ preservation therapy. For high-risk cases after surgery, postoperative radiotherapy or chemoradiotherapy can reduce the risk of locoregional recurrence. Physical exam, including laryngoscopy, is an essential part of pre-treatment evaluation and is critical for the assessment of the airway, fixation of the vocal cords, and target delineation. Imaging, including thin-cut CTs of the larynx, PET/CT, and MRI, may help in identifying lymph node metastases, paraglottic extension, and subglottic extension. This chapter discusses general principles of target delineation for a variety of common clinical scenarios. Detailed, slice-by-slice cases are shown for early-stage disease, organ preservation in advanced disease, and postoperative radiotherapy after total laryngectomy.
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Fan, D., Kang, J.J., Yu, Y., Cahlon, O., Riaz, N., Lee, N.Y. (2022). Larynx Cancer. In: Lee, N.Y., Lu, J.J., Yu, Y. (eds) Target Volume Delineation and Field Setup. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-99590-4_4
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DOI: https://doi.org/10.1007/978-3-030-99590-4_4
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