Abstract
Modern radiotherapy for NSCLC and SCLC involves the synthesis of decades of research and experience that have determined the optimal methods for treatment delivery, planning, and reproducibility. Depending on a lung tumor’s histology, the recommended radiation doses and fractionation can vary drastically. In addition, tumor location relative to normal structures and organs-at-risk (OARs), tumor staging, and nodal involvement will influence the radiation delivery method and recommended target volumes. In this chapter, we will discuss our approach to treating lung cancer. We will discuss practical considerations and recommended treatment dosing. Finally, we will provide examples of lung tumors treated with radiotherapy, including diagnostic imaging, OAR contours, target volume contours, and treatment plans.
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References
Chapet O, Kong FM, Quint LE, et al. CT-based definition of thoracic lymph node stations: an atlas from the University of Michigan. Int J Radiat Oncol Biol Phys. 2005;63:170–8.
Ritter T, Quint DJ, Senan S, Gaspar LE, Komaki RU, Hurkmans CW, Timmerman R, Bezjak A, Bradley JD, Movsas B, Marsh L. Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus. Int J Radiat Oncol Biol Phys. 2011;81(5):1442–57.
Kong FM, Ritter T, Quint DJ, et al. Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus. Int J Radiat Oncol Biol Phys. 2011;81(5):1442–57.
Rosenzweig KE, Sim SE, Mychalczak B, et al. Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys. 2001;50:681–5.
Rosenzweig KE, Sura S, Jackson A, et al. Involved-field radiation therapy for inoperable non small-cell lung cancer. J Clin Oncol. 2007;25:5557–61.
Yuan S, Sun X, Li M, et al. A randomized study of involved-field irradiation versus elec- tive nodal irradiation in combination with concurrent chemotherapy for inoperable stage III nonsmall cell lung cancer. Am J Clin Oncol. 2007;30:239–44.
Giraud P, Antoine M, Larrouy A, et al. Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning. Int J Radiat Oncol Biol Phys. 2000;48:1015–24.
Spoelstra FO, Senan S, Le Pechoux C, et al. Variations in target volume definition for postoperative radiotherapy in stage III non-small-cell lung cancer: analysis of an international contouring study. Int J Radiat Oncol Biol Phys. 2009;76:1106–13.
Marks LB, Yorke ED, Jackson A, et al. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys. 2010;76:S10–9.
American Joint Committee. Cancer staging manual. 8th ed. New York: Springer; 2010.
Rusch VW, Asamura H, Watanabe H, Giroux DJ, Rami-Porta R, Goldstraw P. The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer. J Thorac Oncol. 2009;4(5):568–77.
Watanabe Y, Shimizu J, Tsubota M, Iwa T. Mediastinal spread of metastatic lymph nodes in bronchogenic carcinoma: mediastinal nodal metastases in lung cancer. Chest. 1990;97(5):1059–65.
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Wijetunga, N.A., Liao, Z., Gomez, D.R. (2022). Lung Cancer. In: Lee, N.Y., Lu, J.J., Yu, Y. (eds) Target Volume Delineation and Field Setup. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-99590-4_13
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DOI: https://doi.org/10.1007/978-3-030-99590-4_13
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