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Primary Prevention: Smoking

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Cardiovascular Risk Assessment in Primary Prevention

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Tobacco use is the leading preventable cause of morbidity and mortality worldwide, and smoking cessation can reduce this impact, decreasing cardiovascular as well as cancer deaths. Exposure to tobacco, including secondhand smoke, promotes the progression of atherosclerosis and contributes to increased thrombogenicity and inflammation and thereby increases cardiovascular risk. Smoking cessation should be a priority for all health-care providers at each patient encounter to maximize the success rate for smoking cessation. Tools such as counseling, nicotine replacement therapy, and medications such as bupropion and varenicline can improve quit rates.

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References

  • Ahmed AA, Patel K, Nyaku MA, Kheirbek RE, Bittner V, et al. Risk of heart failure and death after prolonged smoking cessation: role of amount and duration of prior smoking. Circ Heart Fail. 2015;8(4):694–701.

    Article  Google Scholar 

  • Anthenelli RM, Gaffney M, Benowitz NL, West R, McRae T, Russ C, Lawrence D, St Aubin L, Krishen A, Evins AE. Predictors of neuropsychiatric adverse events with smoking cessation medications in the randomized controlled EAGLES trial. J Gen Intern Med. 2019;34(6):862–70.

    Article  Google Scholar 

  • Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Goldberger ZD, Hahn EJ, Himmelfarb CD, Khera A, Lloyd-Jones D, McEvoy JW, Michos ED, Miedema MD, Muñoz D, Smith SC Jr, Virani SS, Williams KA Sr, Yeboah J, Ziaeian B. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. Circulation. 2019;140(11):e596–646. https://doi.org/10.1161/CIR.0000000000000678. Epub 2019 Mar 17. Erratum in: Circulation. 2019;140(11):e649–e650. Erratum in: Circulation. 2020;141(4):e60. Erratum in: Circulation. 2020 Apr 21;141(16):e774. PMID: 30879355; PMCID: PMC7734661.

    Article  PubMed  PubMed Central  Google Scholar 

  • Asthana A, Johnson HM, Piper ME, Fiore MC, Baker TB, et al. Effects of smoking intensity ad cessation on inflammatory markers in a larger cohort of active smokers. Am Heart J. 2010;160:458–63.

    Article  Google Scholar 

  • Babb S, Malarcher A, Schauer G, Asman K, Jamal A. Quitting smoking among adults—United States, 2000–2015. Morb Mortal Wkly Rep. 2017;65(52):1457–64.

    Article  Google Scholar 

  • Barbieri SS, Zacchi E, Amadio P, Gianellini S, Mussoni L, Weksler BB, Tremoli E. Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction. Cardiovasc Res. 2011;90(3):475–83.

    Article  CAS  Google Scholar 

  • Barnoya J, Glantz SA. Cardiovascular effects of secondhand smoke: nearly as large as smoking. Circulation. 2005;111:2684–98.

    Article  Google Scholar 

  • Barua RS, Rigotti NA, Benowitz NL, Cummings KM, Jazayeri MA, Morris PB, Ratchford EV, Sarna L, Stecker EC, Wiggins BS. 2018 ACC expert consensus decision pathway on tobacco cessation treatment: a report of the American College of Cardiology task force on clinical expert consensus documents. J Am Coll Cardiol. 2018;72(25):3332–65. https://doi.org/10.1016/j.jacc.2018.10.027.

    Article  PubMed  Google Scholar 

  • Black N, Johnston M, Michie S, Hartmann-Boyce J, et al. Behaviour change techniques associated with smoking cessation in intervention and comparator groups of randomized controlled trials: a systemic review and meta-regression. Addiction. 2020;115:2008–20.

    Article  Google Scholar 

  • Burden of Cigarette Use in the US/data and statistics-CDC. https://www.cdc.gov › tobacco › data_statistics.

  • Cahill K, Stevens S, Perera R, Lancaster T. Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2013;2013(5):CD009329. https://doi.org/10.1002/14651858.CD009329.pub2. PMID: 23728690; PMCID: PMC8406789.

    Article  PubMed Central  Google Scholar 

  • Chen T, Li W, Wang Y, Xu B, Guo J. Smoking status on outcomes after percutaneous coronary intervention. Clin Cardiol. 2012;35(9):570–4.

    Article  Google Scholar 

  • Chow CK, Jolly S, Rao-Melachini P, Fox KA, Arand SS, et al. Associate of diet, exercise, and smoking modification with risk of early cardiovascular events after acute coronary syndromes. Circulation. 2010;121:750–8.

    Article  Google Scholar 

  • Cobos-Campos R, de Lafuente AS, Apiñaniz A, Parraza N, Llanos IP, Orive G. Effectiveness of mobile applications to quit smoking: systematic review and meta-analysis. Tob Prev Cessat. 2020;6:62.

    Article  Google Scholar 

  • Cornelius ME, Wang TW, Jamal A, Loretan CG, Neff LJ. Tobacco product use among adults-United States, 2019. MMWR Morb Mortal Wkly Rep. 2019;69:1736–42.

    Article  Google Scholar 

  • Doll R, Peto R, Wheatley K, Gray R, Sutherland I. Mortality in relation to smoking: 40 years’ observations on male British doctors. BMJ. 1994;309:901–11.

    Article  CAS  Google Scholar 

  • Duncan MS, Freiberg MS, Greevy RA Jr, Kundu S, Vasan RS, Tindle HA. Association of smoking cessation with subsequent risk of cardiovascular disease. JAMA. 2019;322(7):642–50.

    Article  Google Scholar 

  • GBD 2015 Tobacco Collaborators. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015; a systemic analysis from the Global Burden of Disease Study 2015. Lancet. 2017;389:1885–906.

    Google Scholar 

  • Gepner AD, Piper ME, Johnson HM, Fiore MC, Baker TB, Stein JH. Effects of smoking and smoking cessation on lipids and lipoproteins: outcomes from a randomized clinical trial. Am Heart J. 2011;161(1):145–51.

    Article  CAS  Google Scholar 

  • Gerber Y, Rosen LJ, Goulbourt U, Benyamini Y, Drory Y, Israel Study Group on First Acute Myocardial Infarction. Smoking status and long-term survival after first acute myocardial infarction a population-based cohort study. J Am Coll Cardiol. 2009;54(25):2382–7.

    Article  Google Scholar 

  • Grabovac I, Oberndorfer M, Fischer J, Wiesinger W, Haider S, Dorner TE. Effectiveness of electronic cigarettes in smoking cessation: a systematic review and meta-analysis. Nicotine Tob Res. 2021;23(4):625–34.

    Article  CAS  Google Scholar 

  • Hackshaw A, Morris JK, Boniface S, Tang JL, Milenkovic D. Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports. BMJ. 2018;360:j5855.

    Article  Google Scholar 

  • Haddock CK, Poston WS, Taylor JE, Conard M, Spertus J. Smoking and health outcomes after percutaneous coronary intervention. Am Heart J. 2003;145(4):652–7.

    Article  Google Scholar 

  • Hartmann-Boyce J, Hong B, Livingstone-Banks J, Wheat H, Fanshawe TR. Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation. Cochrane Database Syst Rev. 2019;6(6):CD009670. https://doi.org/10.1002/14651858.CD009670.pub4.

    Article  PubMed  Google Scholar 

  • Hartmann-Boyce J, Livingstone-Banks J, Ordóñez-Mena JM, Fanshawe TR, Lindson N, Freeman SC, Sutton AJ, Theodoulou A, Aveyard P. Behavioural interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2021;1:CD013229. https://doi.org/10.1002/14651858.CD013229.pub2.

    Article  PubMed  Google Scholar 

  • Hasdai D, Garratt KN, Grill DE, Lerman A, Holmes DR Jr. Effect of smoking status on the long-term outcomes after successful percutaneous coronary revascularization. NEJM. 1997;336:755–61.

    Article  CAS  Google Scholar 

  • https://www.ahrq.gov/sites/default/files/wysiwyg/professionals/clinicians-providers/guidelines-recommendations/tobacco/5rs.pdf.

  • Jamal A, Gentzke A, Hu SS, Cullen KA, Apelberg BJ, et al. Tobacco use among middle and high school students – United States, 2011–2016. MMWR Morb Mortal Wkly Rep. 2017;66:597–603.

    Article  Google Scholar 

  • Jamal A, Phillips E, Gentzke AS, Homa DM, Babb SD, King BA, Neff LJ. Current cigarette smoking among adults—United States, 2016. Morb Mortal Wkly Rep. 2018;67(2):53.

    Article  Google Scholar 

  • Jefferis BJ, Lowe GD, Welsh P, Rumley A, Lawlor DA, Ebrahim S, Carson C, Doig M, Feyerabend C, McMeekin L, Wannamethee SG. Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis. 2010;208(2):550–6.

    Article  CAS  Google Scholar 

  • Jha P, Ramasundarahettige C, Landsman V, Rostron B, Thun M, et al. 21st-century hazards of smoking and benefits of cessation in the United States. N Engl J Med. 2013;368:341–50.

    Article  CAS  Google Scholar 

  • Johnson HM, Gossett LK, Piper ME, Aeschlimann SE, Korcarz CE, et al. Effects of smoking and smoking cessation on endothelial function: 1-year outcomes from a randomized clinical trial. J Am Coll Cardiol. 2010;55(18):1988–95.

    Article  CAS  Google Scholar 

  • Jorenby DE, Leischow SJ, Nides MA, Rennard SI, Johnston JA, Hughes AR, Smith SS, Muramoto ML, Daughton DM, Doan K, Fiore MC, Baker TB. A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. N Engl J Med. 1999;340(9):685–91.

    Article  CAS  Google Scholar 

  • Kalio K, Jokinen E, Saarien M, Hamalainen M, Volanen I, et al. Arterial intima-media thickness, endothelial function, and apolipoproteins in adolescents frequently exposed to tobacco smoke. Circ Cardiovasc Qual Outcomes. 2010;3:196–203.

    Article  Google Scholar 

  • Kalkhoran S, Benowitz NL, Rigotti NA. Prevention and treatment of tobacco use: JACC health promotion series. JACC. 2018;72:1030–45.

    Article  Google Scholar 

  • Law MR, Wald NJ. Environmental tobacco smoke and ischemic heart disease. Prog Cardiovasc Dis. 2003;46:31–8.

    Article  Google Scholar 

  • Lindson N, Chepkin SC, Ye W, Fanshawe TR, Bullen C, Hartmann-Boyce J. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2019;4(4):CD013308.

    PubMed  Google Scholar 

  • Matkin W, Ordóñez-Mena JM, Hartmann-Boyce J. Telephone counselling for smoking cessation. Cochrane Database Syst Rev. 2019;5(5):CD002850. https://doi.org/10.1002/14651858.CD002850.pub4.

    Article  PubMed  Google Scholar 

  • Middlekauff HR. Cardiovascular impact of electronic-cigarette use. Trends Cardiovasc Med. 2020;30(3):133–40.

    Article  CAS  Google Scholar 

  • Mills EJ, Wu P, Lockhart I, Thorlund K, Puhan M, Ebbert JO. Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis. Ann Med. 2012;44(6):588–97.

    Article  CAS  Google Scholar 

  • Notley C, Gentry S, Livingstone-Banks J, Bauld L, Perera R, Hartmann-Boyce J. Incentives for smoking cessation. Cochrane Database Syst Rev. 2019;7(7):CD004307. https://doi.org/10.1002/14651858.CD004307.pub6. PMID: 31313293; PMCID: PMC6635501.

    Article  PubMed  Google Scholar 

  • Oono IP, Mackay DF, Pell JP. Meta-analysis of the association between secondhand smoke exposure and stroke. J Public Health. 2011;33:496–502.

    Article  CAS  Google Scholar 

  • Patnode CD, Henderson JT, Melnikow J, et al. Interventions for tobacco cessation in adults, including pregnant women: an evidence update for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Jan. (Evidence Synthesis, No. 196.) Chapter 2, Methods. Available from: https://www.ncbi.nlm.nih.gov/books/NBK567061/.

  • Prochaska JO, DiClemente CC, Norcross JC. In search of how people change. Applications to addictive behaviors. Am Psychol. 1992;47(9):1102–14.

    Article  CAS  Google Scholar 

  • Rajani NB, Mastellos N, Filippidis FT. Impact of gamification on the self-efficacy and motivation to quit of smokers: observational study of two gamified smoking cessation mobile apps. JMIR Serious Games. 2021;9(2):e27290.

    Article  Google Scholar 

  • Reid ZZ, Regan S, Kelley JH, Streck JM, Ylioja T, Tindle HA, Chang Y, Levy DE, Park ER, Singer DE, Carpenter KM. Comparative effectiveness of post-discharge strategies for hospitalized smokers: study protocol for the Helping HAND 2 randomized controlled trial. BMC Public Health. 2015;15(1):1–2.

    Article  Google Scholar 

  • Sadeghi R, Mokhber N, Mahmoudi LZ, Asgharipour N, Seyfi H. A systematic review and meta-analysis on controlled treatment trials of metacognitive therapy for anxiety disorders. J Res Med Sci. 2015;20(9):901–9.

    Article  CAS  Google Scholar 

  • Shah AM, Pfeffer MA, Hartley LH, Moye LA, Gersh BJ, et al. Risk of all-cause of all-cause mortality, recurrent myocardial infarction, and heart failure hospitalization associated with smoking status following myocardial infarction with left ventricular dysfunction. Am J Cardiol. 2010;106(7):911–6.

    Article  Google Scholar 

  • Thomson G, Eberson J, Lacey B, Peto R, Woodward M, et al. Childhood smoking ,adult cessation, and cardiovascular mortality: prospective study of 390,000 US adults. J Am Heart Assoc. 2020;9(21):e018431. https://doi.org/10.1161/JAHA.120.018431. Epub 2020 Oct 28. PMID: 33108954; PMCID: PMC7763404.

    Article  PubMed  PubMed Central  Google Scholar 

  • Thun MJ, Carter BD, Feskanich D, Freedman ND, Prentice R, et al. 50- year trends in smoking related mortality in the United States. NEJM. 2013;368:351–64.

    Article  CAS  Google Scholar 

  • US Department of Health and Human Services. The health consequences of smoking-50 years of progress: a report of the surgeon general. US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2014.

    Google Scholar 

  • Villanti AC, West JC, Klemperer EM, Graham AL, Mays D, Mermelstein RJ, Higgins ST. Smoking-cessation interventions for U.S. young adults: updated systematic review. Am J Prev Med. 2020;59(1):123–36.

    Article  Google Scholar 

  • www.ahrq.gov/sites/default/files/wysiwyg/professionals/clinicians-providers/guidelines-recommendations/tobacco/5steps.pdf https://www.ahrq.gov/.

  • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study) case-control study. Lancet. 2004;364:937–52.

    Article  Google Scholar 

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Authors and Affiliations

  1. Division of Cardiology, Brigham and Women’s Hospital, Boston, MA, USA

    Donna Polk

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  1. Donna Polk
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Correspondence to Donna Polk .

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  1. Section on Cardiovascular Disease, Wake Forest University School of Medicine, Winston Salem, NC, USA

    Michael D. Shapiro

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Polk, D. (2022). Primary Prevention: Smoking. In: Shapiro, M.D. (eds) Cardiovascular Risk Assessment in Primary Prevention. Contemporary Cardiology. Humana, Cham. https://doi.org/10.1007/978-3-030-98824-1_7

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  • DOI: https://doi.org/10.1007/978-3-030-98824-1_7

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