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A Multipurpose Medicinal Plant Species: Tinospora cordifolia (Willd.) Miers

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Medicinal and Aromatic Plants of India Vol. 1

Part of the book series: Medicinal and Aromatic Plants of the World ((MAPW,volume 8))

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Abstract

Tinospora cordifolia (Willd.) Miers (Fam. – Menispermaceae) is a perennial, dioecious, deciduous climber found in India. It is used in the treatment of jaundice, fever, urinary diseases, asthma, gout, diabetes, diarrhoea, skin disease, rheumatism, and snakebites. The crude extracts of T. cordifolia are used in the treatment of bone fracture, wound healing, jaundice, fever, urinary diseases, asthma, gout, diabetes, diarrhoea, and skin diseases. Various chemical constituents have been identified from T. cordifolia viz., tinoscorside A-D, berberine, jatrorrhizine, cordifoliside A-B, and amritoside A-D. The crude extracts and isolated compounds possess antimicrobial, anti-inflammatory, antioxidant, antirheumatic, and antidiabetic properties. In clinical trials, T. cordifolia extracts reduced the fasting blood glucose levels in the type-2 diabetic patients and also restored the changed liver functions of patients, although the drug itself, demonstrated mild to moderate adverse changes (in kidney, liver, intestine, and stomach) at a therapeutic equivalent dose (×10 dose level). The anti-inflammatory, antidiabetic, antimicrobial, anticancer, antistress, and antioxidant activities of T. cordifolius have been evaluated. Farther clinical applications should be preceeded by in vivo model studies on the safety, potent doses, bioactive molecules, and the mechanisms of actions.

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  1. Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, India

    Bharat Singh & Vinay Sharma

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  1. Bharat Singh
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  1. Faculty of Agr. & Food Sc., Széchenyi István University, Mosonmagyaróvár, Hungary

    Ákos Máthé

  2. Nawab Shah Alam Khan Centre for Post Graduate Studies and Research, Affiliated to Osmania University, Hyderabad, Telangana, India

    Irfan Ali Khan

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Singh, B., Sharma, V. (2022). A Multipurpose Medicinal Plant Species: Tinospora cordifolia (Willd.) Miers. In: Máthé, Á., Khan, I.A. (eds) Medicinal and Aromatic Plants of India Vol. 1. Medicinal and Aromatic Plants of the World, vol 8. Springer, Cham. https://doi.org/10.1007/978-3-030-98701-5_14

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