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Dihydrokaempferol: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology

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Handbook of Dietary Flavonoids

Abstract

Identifying and characterizing physiologically active chemicals from plant extracts for use in the pharmaceutical industry as well as in the promotion of sustainable diets has become progressively important to researchers. Flavonoids have long been known for their anti-inflammatory and antioxidant properties. Phytoconstituents research of various herbal medications has determined the presence of flavonoids such as kaempferol and its derivatives. Dihydrokaempferol (DHK) is one such flavonoid that may be found in a wide range of foods, fruits, plants, and natural sources. Because of its hydrophilic nature, dihydrokaempferol’s absorption is enhanced by passive diffusion, although study reveals that it may also be absorbed by facilitated dispersion across the membrane. It is known to possess the multiple biological properties including but not limited to anticancer, antihyperglycaemic, anti-inflammatory, and neuroprotective. This chapter in contrast highlights the latest research on dihydrokaempferol’s resources, biosynthesis pathway, bioavailability, biocompatibility, and pharmaceutics to give an insight to the readers and researchers.

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  1. Rajeev K. Singla, Hitesh Chopra and Ankit Kumar Dubey contributed equally with all other contributors.

Authors and Affiliations

  1. Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China

    Rajeev K. Singla, Ankit Kumar Dubey & Bairong Shen

  2. iGlobal Research and Publishing Foundation, New Delhi, India

    Ankit Kumar Dubey

  3. Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India

    Hitesh Chopra

  4. School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India

    Rajeev K. Singla

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  1. Rajeev K. Singla
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  2. Hitesh Chopra
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  3. Ankit Kumar Dubey
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  4. Bairong Shen
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Correspondence to Bairong Shen .

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  1. Department of Analytical Chemistry and Food Science, Universidade de Vigo, Vigo, Spain

    Jianbo Xiao

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Singla, R.K., Chopra, H., Dubey, A.K., Shen, B. (2023). Dihydrokaempferol: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology. In: Xiao, J. (eds) Handbook of Dietary Flavonoids. Springer, Cham. https://doi.org/10.1007/978-3-030-94753-8_87-1

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