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Xanthohumol: Recent Advances on Resources, Biosynthesis, Bioavailability and Pharmacology

Biosynthesis Pathway and Pharmacology

  • Living reference work entry
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Handbook of Dietary Flavonoids

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Abstract

Xanthohumol is a prenylated flavonoid derived from the female flowers of the hop plant (Humulus lupulus L.) species in the family Cannabaceae, with potential pharmacological activities. Xanthohumol, a bitter tasting compound, belongs to a flavonoid class of secondary metabolites and particularly to a subclass of chalcone precursors of flavonoids. Investigations by academic and industrial scientists have generated keen interest in its useful properties in food, beverages, and medicine. Animal and human studies of xanthohumol have revealed its diverse biological features, including anti-inflammatory, anti-cancer, anti-oxidant, and anti-diabetic activities, as well as other related properties. The safety of xanthohumol is almost guaranteed, as there is an abundance of data demonstrating its safe use in food and beverages. Xanthohumol and xanthohumol-rich extracts from hops have proven their worth in clinical trials as well as marketed products.

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Authors and Affiliations

  1. Natural Products Chemistry Research Unit, Department of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon

    Maurice Ducret Awouafack

  2. Institute of Natural Medicine, University of Toyama, Toyama, Japan

    Yuan-E Lee & Hiroyuki Morita

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  1. Maurice Ducret Awouafack
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  2. Yuan-E Lee
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Correspondence to Hiroyuki Morita .

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  1. Department of Analytical Chemistry and Food Science, Universidade de Vigo, Vigo, Spain

    Jianbo Xiao

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Awouafack, M.D., Lee, YE., Morita, H. (2023). Xanthohumol: Recent Advances on Resources, Biosynthesis, Bioavailability and Pharmacology. In: Xiao, J. (eds) Handbook of Dietary Flavonoids. Springer, Cham. https://doi.org/10.1007/978-3-030-94753-8_52-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-94753-8

  • Online ISBN: 978-3-030-94753-8

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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