Abstract
I. Description
A. Respiratory distress syndrome (RDS) is a primary pulmonary disorder that accompanies prematurity, specifically immaturity of the lungs, and to a lesser extent the airways. It is a disease of progressive atelectasis, which in its most severe form can lead to severe respiratory failure and death.
B. The incidence and severity of RDS is generally inversely related to gestational age. Approximate incidence:
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Cotton RB. Pathophysiology of hyaline membrane disease (excluding surfactant). In: Polin RA, Fox WW, editors. Fetal and neonatal physiology. 2nd ed. Philadelphia: W.B. Saunders; 1998. p. 1165–74.
Hamvas A. Pathophysiology and management of respiratory distress syndrome. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Neonatal-perinatal medicine. Diseases of the fetus and infant. 9th ed. St Louis: Elsevier Mosby; 2015. p. 1106–16.
Kattwinkel J. Surfactant: evolving issues. Clin Perinatol. 1998;25:17–32.
Martin GI, Sindel BD. Neonatal management of the very low birth weight infant: the use of surfactant. Clin Perinatol. 1992;19:461–8.
Nelson M, Becker MA, Donn SM. Basic neonatal respiratory disorders. In: Donn SM, editor. Neonatal and pediatric pulmonary graphics: principles and clinical applications. Armonk: Futura Publishing Co.; 1998. p. 253–78.
Robertson B, Halliday HL. Principles of surfactant replacement. Biochim Biophys Acta. 1998;1408:346–61.
Walsh MC, Carlo WA, Miller MJ. Respiratory diseases of the newborn. In: Carlo WA, Chatburn RL, editors. Neonatal respiratory care. 2nd ed. Chicago: Year Book Medical Publishers; 1988. p. 260–88.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Donn, S.M. (2022). Respiratory Distress Syndrome. In: Donn, S.M., Mammel, M.C., van Kaam, A.H. (eds) Manual of Neonatal Respiratory Care. Springer, Cham. https://doi.org/10.1007/978-3-030-93997-7_68
Download citation
DOI: https://doi.org/10.1007/978-3-030-93997-7_68
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-93996-0
Online ISBN: 978-3-030-93997-7
eBook Packages: MedicineMedicine (R0)