Abstract
Brunsting-Perry pemphigoid is a form of mucous membrane pemphigoid. To date, the pathogenesis of Brunsting-Perry pemphigoid remains to be elucidated. The role of BP180, type VII collagen, laminin 332, BP230, and LAD-1 has been suggested. The disease is mostly observed in elderly. Men are more commonly affected compared to women. Clinically, Brunsting-Perry pemphigoid is characterized by the bullous and erosive lesions limited to the head, neck, scalp, and upper trunk with mild or no mucosal involvement. In the case of the scalp lesions, scarring alopecia may occur. The diagnosis of Brunsting-Perry pemphigoid is based on the clinical presentation and immunopathological and histopathological examination. Treatment of Brunsting-Perry pemphigoid is similar to the therapy of other forms of pemphigoid. Potent topical corticosteroids are usually the first-line therapeutic option. Low dose methotrexate, tetracyclines or dapsone are recommended for more severe or refractory cases.
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Muszel, M., Sikora, M. (2022). A 67-Year-Old Man with Erosions and Scarring on the Scalp. In: Waśkiel-Burnat, A., Sadoughifar, R., Lotti, T.M., Rudnicka, L. (eds) Clinical Cases in Scalp Disorders. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-93426-2_21
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DOI: https://doi.org/10.1007/978-3-030-93426-2_21
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