Abstract
Frontal fibrosing alopecia, first described by Kossard in the early 1990s, is a form of primary lymphocytic cicatricial alopecia characterized by selective involvement of the frontotemporal hairline and eyebrows. Since the original description, an increasing number of cases have been reported worldwide and the clinical aspects of the disease have been better characterized. However, the pathogenesis is still unknown and several hypotheses have been made about possible triggering factors, including hormones, neurogenic inflammation, smoking, ultraviolet filters, and ingredients in leave-on facial products. A genetic basis has also been hypothesized as the disease can occur in siblings and members of the same family.
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References
Vano-Galvan S, Molina-Riuz AM, Serrano-Falcon C, et al. Frontal fibrosing alopecia: a multicenter review of 355 patients. J Am Acad Dermatol. 2014;70:670–8.
Alegre-Sánchez A, Saceda-Corralo D, Bernárdez C, et al. Frontal fibrosing alopecia in male patients: a report of 12 cases. J Eur Acad Dermatol Venereol. 2017;31:e112–4.
Miteva M, Whiting D, Harries M, et al. Frontal fibrosing alopecia in black patients. Br J Dermatol. 2012;167:208–10.
Dlova N, Jordaan HF, Skenjane A, et al. Frontal fibrosing alopecia: a clinical review of 20 black patients from South Africa. Br J Dermatol. 2013;169:939–41.
Inui S, Nakajima T, Shono F, Itami S. Dermoscopic findings in frontal fibrosing alopecia: report of four cases. Int J Dermatol. 2008;47:796–9.
Kossard S, Lee MS, Wilkinson B. Postmenopausal frontalfibrosing alopecia: a frontal variant of lichen planopilaris. J Am Acad Dermatol. 1997;36:59–66.
Ma SA, Imadojemu S, Beer K, et al. Inflammatory features of frontal fibrosing alopecia. J Cutan Pathol. 2017;44:672–6.
Karnik P, Tekeste Z, McCormick TS, et al. Hair follicle stem cell-specific PPAR-γ deletion causes scarring alopecia. J Investig Dermatol. 2009;129:1243–57.
Moreno-Arrones OM, Saceda-Corralo D, Fonda-Pascual P, et al. Frontal fibrosing alopecia: clinical and prognostic classification. J Eur Acad Dermatol Venereol. 2017;31:1739–45.
Pirmez R, Duque-Estrada B, Abraham LS, et al. It’s not all traction: the pseudo ‘fringe sign’ in frontal fibrosing alopecia. Br J Dermatol. 2015;173:1336–8.
Waśkiel-Burnat A, Rakowska A, Kurzeja M, et al. The value of dermoscopy in diagnosing eyebrow loss in patients with alopecia areata and frontal fibrosing alopecia. J Eur Acad Dermatol Venereol. 2018;33(1):213–9. https://doi.org/10.1111/jdv.15279.
Toledo-Pastrana T, Garcia-Hernandez MJ, Camacho-Martinez F. Perifollicular erythema as trichoscopy sign of progression in frontal fibrosing alopecia. Int J Trichol. 2013;5:151–3.
Fernandez-Crehuet P, Rodrigues-Barata AR, Vano-Galvan S, et al. Trichoscopic features of frontal fibrosing alopecia: results in 249 patients. J Am Acad Dermatol. 2015;72:357–9.
Doche I, Valente NS, Romiti R, Hordinsky M. “Normal-appearing” scalp areas are also affected in lichen planopilaris and frontal fibrosing alopecia: an observational histopathologic study of 40 patients. Clin Exp Dermatol. 2018;29(3):278–81. https://doi.org/10.1111/exd.13834.
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Ammar, A.M., Ibrahim, S.M., Elsaie, M.L. (2022). A 58-Year-Old Man with Alopecia on the Frontal Area. In: Waśkiel-Burnat, A., Sadoughifar, R., Lotti, T.M., Rudnicka, L. (eds) Clinical Cases in Hair Disorders. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-93423-1_25
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DOI: https://doi.org/10.1007/978-3-030-93423-1_25
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