Skip to main content
SpringerLink
Log in

Office-Based Injection Laryngoplasty

  • Chapter
  • First Online:
Office-Based Laryngeal Surgery

Abstract

Injection laryngoplasty is performed for treatment of vocal fold paralysis/paresis, atrophy, bowing, scar and/or sulcus vocalis, and other causes of glotti

c insufficiency or dysphonia. Recent advances in technology have facilitated the performance of this procedure in an office setting while the patient is awake. The most commonly adopted approaches are the peroral approach; the transcervical approach, via the thyroid cartilage referred to as transthyroid (TT), via the thyrohyoid membrane (TH), or via the cricothyroid membrane (CT); and the transnasal fiberoptic approach using a flexible endoscope with a working channel. The choice of approach depends on the patient’s tolerance and anatomic variations, physician’s expertise, the viscosity and volume of the material to be injected, and the availability of resources. Coincident with the evolution in surgical approaches and techniques, different types of injectate substances have been introduced over the last few decades, each with its advantages and limitations. The main challenges in finding the ideal filling substance are biocompatibility, availability, ease of harvesting, and cost. The choice of injection material also varies with the desired duration of effect. Injection laryngoplasty may be temporary if nerve recovery within 1 year is anticipated or may be long-lasting for patients with transection of the recurrent laryngeal nerve, for example.

This chapter reviews the timing of injection laryngoplasty, as well as the surgical outcomes and complications reported with the use of different substances. The impact of age, gender, and other patient-related factors is stressed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bruening W. Uber eine neue Behanlungsmethode der Rekurrenslahmung. Ver Deutsch Laryng. 1991:18–23.

    Google Scholar 

  2. Arnold GE. Vocal rehabilitation of paralytic dysphonia: I. cartilage injection into a paralyzed vocal cord. Arch Otolaryngol. 1955;62(1):1–17.

    Article  CAS  Google Scholar 

  3. Courey MS. Injection laryngoplasty. Otolaryngol Clin N Am. 2004;37(1):121–38.

    Article  Google Scholar 

  4. Zeitler DM, Amin MR. The thyrohyoid approach to in-office injection augmentation of the vocal fold. Curr Opin Otolaryngol Head Neck Surg. 2007;15(6):412–6.

    Article  PubMed  Google Scholar 

  5. Rosen CA, Amin MR, Sulica L, et al. Advances in office-based diagnosis and treatment in laryngology. Laryngoscope. 2009;119(S2):S185–212.

    Article  PubMed  Google Scholar 

  6. Sulica L, Rosen CA, Postma GN, et al. Current practice in injection augmentation of the vocal folds: indications, treatment principles, techniques, and complications. Laryngoscope. 2010;120(2):319–25.

    Article  PubMed  Google Scholar 

  7. Reich AR, Lerman JW. Teflon laryngoplasty: an acoustical and perceptual study. J Speech Hear Disord. 1978;43(4):496–505.

    Article  CAS  PubMed  Google Scholar 

  8. Montgomery WW. Laryngeal paralysis Teflon® injection. Ann Otol Rhinol Laryngol. 1979;88(5):647–57.

    Article  CAS  PubMed  Google Scholar 

  9. Ellis JC, Mccaffrey TV, Desanto LW, Reiman HV. Migration of Teflon after vocal cord injection. Otolaryngol Head Neck Surg. 1987;96(1):63–6.

    Article  CAS  PubMed  Google Scholar 

  10. Dedo HH, Carlsouou B. Histologic evaluation of Teflon granulomas of human vocal cords: a light and electron microscopic study. Acta Otolaryngol. 1982;93(1–6):475–84.

    Article  CAS  PubMed  Google Scholar 

  11. Matton G, Anseeuw A, De Keyser F. The history of injectable biomaterials and the biology of collagen. Aesthet Plast Surg. 1985;9(2):133–40.

    Article  CAS  Google Scholar 

  12. Woodson G. Evolving concepts of laryngeal paralysis. J Laryngol Otol. 2008;122(5):437–41.

    Article  CAS  PubMed  Google Scholar 

  13. Blitzer A, Jahn AF, Keidar A. Semon's law revisited: an electromyographic analysis of laryngeal synkinesis. Ann Otol Rhinol Laryngol. 1996;105(10):764–9.

    Article  CAS  PubMed  Google Scholar 

  14. Sataloff RT, Praneetvatakul P, Heuer RJ, et al. Laryngeal electromyography: clinical application. J Voice. 2010;24(2):228–34.

    Article  PubMed  Google Scholar 

  15. Behlau M, Oliveira G. Vocal hygiene for the voice professional. Curr Opin Otolaryngol Head Neck Surg. 2009;17(3):149–54.

    Article  PubMed  Google Scholar 

  16. Rosen B, Horman M, Sataloff RT. Voice therapy. In: Sataloff RT, editor. Professional voice: the science and art of clinical care. 4th ed. San Diego, CA: Plural Publishing; 2017. p. 1171–94.

    Google Scholar 

  17. Yung KC, Likhterov I, Courey MS. Effect of temporary vocal fold injection medialization on the rate of permanent medialization laryngoplasty in unilateral vocal fold paralysis patients. Laryngoscope. 2011;121(10):2191–4.

    Article  PubMed  Google Scholar 

  18. Prendes BL, Yung KC, Likhterov I, Schneider SL, Al-Jurf SA, Courey MS. Long-term effects of injection laryngoplasty with a temporary agent on voice quality and vocal fold position. Laryngoscope. 2012;122(10):2227–33.

    Article  PubMed  Google Scholar 

  19. Milstein CF, Akst LM, Hicks MD, Abelson TI, Strome M. Long-term effects of micronized Alloderm injection for unilateral vocal fold paralysis. Laryngoscope. 2005;115(9):1691–6.

    Article  CAS  PubMed  Google Scholar 

  20. Borzacchiello A, Mayol L, Gärskog O, Dahlqvist Å, Ambrosio L. Evaluation of injection augmentation treatment of hyaluronic acid based materials on rabbit vocal folds viscoelasticity. J Mater Sci Mater Med. 2005;16(6):553–7.

    Article  CAS  PubMed  Google Scholar 

  21. Francis DO, Williamson K, Hovis K, et al. Effect of injection augmentation on need for framework surgery in unilateral vocal fold paralysis. Laryngoscope. 2016;126(1):128–34.

    Article  PubMed  Google Scholar 

  22. Merea VS, Husain S, Sulica L. Medialization laryngoplasty after injection augmentation. J Voice. 2018;32(2):249–55.

    Article  Google Scholar 

  23. Vila PM, Bhatt NK, Paniello RC. Early-injection laryngoplasty may lower risk of thyroplasty: a systematic review and meta-analysis. Laryngoscope. 2018;128(4):935–40.

    Article  PubMed  Google Scholar 

  24. Berke GS, Gerratt B, Kreiman J, Jackson K. Treatment of Parkinson hypophonia with percutaneous collagen augmentation. Laryngoscope. 1999;109(8):1295–9.

    Article  CAS  PubMed  Google Scholar 

  25. Luu Q, Tsai V, Mangunta V, Berke GS, Chhetri DK. Safety of percutaneous injection of bovine dermal crosslinked collagen for glottic insufficiency. Otolaryngol Head Neck Surg. 2007;136(3):445–9.

    Article  PubMed  Google Scholar 

  26. Kimura M, Nito T, Sakakibara KI, Tayama N, Niimi S. Clinical experience with collagen injection of the vocal fold: a study of 155 patients. Auris Nasus Larynx. 2008;35(1):67–75.

    Article  PubMed  Google Scholar 

  27. Min JY, Hong SD, Kim K, Son YI. Long-term results of Artecoll injection laryngoplasty for patients with unilateral vocal fold motion impairment: safety and clinical efficacy. Arch Otolaryngol Head Neck Surg. 2008;134(5):490–6.

    Article  PubMed  Google Scholar 

  28. Dursun G, Boynukalin S, Ozgursoy OB, Coruh I. Long-term results of different treatment modalities for glottic insufficiency. Am J Otolaryngol. 2008;29(1):7–12.

    Article  PubMed  Google Scholar 

  29. Gillespie MB, Dozier TS, Day TA, Martin-Harris B, Nguyen SA. Effectiveness of calcium hydroxylapatite paste in vocal rehabilitation. Ann Otol Rhinol Laryngol. 2009;118(8):546–51.

    Article  PubMed  Google Scholar 

  30. Carroll TL, Rosen CA. Long-term results of calcium hydroxylapatite for vocal fold augmentation. Laryngoscope. 2011;121(2):313–9.

    Article  CAS  PubMed  Google Scholar 

  31. Choi J, Son YI, So YK, Byun H, Lee EK, Yun YS. Posterior glottic gap and age as factors predicting voice outcome of injection laryngoplasty in patients with unilateral vocal fold paralysis. J Laryngol Otol. 2012;126(3):260–6.

    Article  CAS  PubMed  Google Scholar 

  32. Wen MH, Cheng PW, Liao LJ, Chou HW, Wang CT. Treatment outcomes of injection laryngoplasty using cross-linked porcine collagen and hyaluronic acid. Otolaryngol Head Neck Surg. 2013;149(6):900–6.

    Article  PubMed  Google Scholar 

  33. Birkent H, Sardesai M, Hu A, Merati AL. Prospective study of voice outcomes and patient tolerance of in-office percutaneous injection laryngoplasty. Laryngoscope. 2013l;123(7):1759–62.

    Article  PubMed  Google Scholar 

  34. Jamal N, Mundi J, Chhetri DK. Higher risk of superficial injection during injection laryngoplasty in women. Am J Otolaryngol. 2014;35(2):159–63.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Woo SH, Son YI, Lee SH, Park JJ, Pyeong Kim J. Comparative analysis on the efficiency of the injection laryngoplasty technique using calcium hydroxyapatite (CaHA): the thyrohyoid approach versus the cricothyroid approach. J Voice. 2013;27(2):236–41.

    Article  PubMed  Google Scholar 

  36. Powell J, Carding P, Birdi R, Wilson JA. Injection laryngoplasty in the outpatient clinic under local anaesthetic: a case series of sixty-eight patients. Clin Otolaryngol. 2014;39(4):224–7.

    Article  CAS  PubMed  Google Scholar 

  37. Halderman AA, Bryson PC, Benninger MS, Chota R. Safety and length of benefit of restylane for office-based injection medialization—a retrospective review of one institution's experience. J Voice. 2014;28(5):631–5.

    Article  PubMed  Google Scholar 

  38. Sardesai MG, Merati AL, Hu A, Birkent H. Impact of patient-related factors on the outcomes of office-based injection laryngoplasty. Laryngoscope. 2016;126(8):1806–9.

    Article  PubMed  Google Scholar 

  39. McLaughlin CW, Swendseid B, Courey MS, Schneider S, Gartner-Schmidt JL, Yung KC. Long-term outcomes in unilateral vocal fold paralysis patients. Laryngoscope. 2018;128(2):430–6.

    Article  PubMed  Google Scholar 

  40. Sielska-Badurek EM, Sobol M, Jędra K, Rzepakowska A, Osuch-Wojcikiewicz E, Niemczyk K. Injection laryngoplasty as miniinvasive office-based surgery in patients with unilateral vocal fold paralysis–voice quality outcomes. Wideochir Inne Tech Maloinwazyjne. 2017;12(3):277–84.

    PubMed  PubMed Central  Google Scholar 

  41. Hu HC, Hung YT, Lin SY, Tung TH, Chang SY. Office-based autologous fat injection laryngoplasty for glottic insufficiency in patients under 50 years old. J Voice. 2019;33(5):747–50.

    Article  PubMed  Google Scholar 

  42. Maccarini AR, Stacchini M, Mozzanica F, et al. Efficacy of trans-nasal fiberendoscopic injection laryngoplasty with centrifuged autologous fat in the treatment of glottic insufficiency due to unilateral vocal fold paralysis. Acta Otorhinolaryngol Ital. 2018;38(3):204–13.

    Article  PubMed Central  Google Scholar 

  43. Hamdan AL, Rizk M, Khalife E, Ziade G, Kasti M. Voice outcome measures after flexible endoscopic injection laryngoplasty. World J Otorhinolaryngol Head Neck Surg. 2018;4(2):130–4.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Sato T, Nito T, Ueha R, Goto T, Yamasoba T. Investigation of the safety of injection laryngoplasty under antithrombotic therapy. ORL J Otorhinolaryngol Relat Spec. 2019;81(4):215–23.

    Article  CAS  PubMed  Google Scholar 

  45. Bertroche JT, Radder M, Kallogjeri D, Paniello RC, Bradley JP. Patient-defined duration of benefit from juvederm (hyaluronic acid) used in injection laryngoplasty. Laryngoscope. 2019;129(12):2744–7.

    Article  CAS  PubMed  Google Scholar 

  46. Jeong GE, Lee DH, Lee YS, et al. Treatment efficacy of voice therapy following injection laryngoplasty for unilateral vocal fold paralysis. J Voice. 2020:S0892-1997(20)30188-0.

    Google Scholar 

  47. Novakovic D, Nguyen DD, Chacon A, Madill C. Injection laryngoplasty as adjunct treatment method for muscle tension dysphonia: preliminary findings. Laryngoscope. 2020;130(4):980–5.

    Article  PubMed  Google Scholar 

  48. Wang CC, Wu SH, Tu YK, Lin WJ, Liu SA. Hyaluronic acid injection Laryngoplasty for unilateral vocal fold paralysis—a systematic review and meta-analysis. Cell. 2020;9(11):2417.

    Article  CAS  Google Scholar 

  49. Zuniga S, Ebersole B, Jamal N. Improved swallow outcomes after injection laryngoplasty in unilateral vocal fold immobility. Ear Nose Throat J. 2018;97(8):250–6.

    Article  PubMed  Google Scholar 

  50. Anis MM, Memon Z. Injection medialization laryngoplasty improves dysphagia in patients with unilateral vocal fold immobility. World J Otorhinolaryngol Head Neck Surg. 2018;4(2):126–9.

    Article  PubMed  PubMed Central  Google Scholar 

  51. Han YJ, Jang YJ, Park GY, Joo YH, Im S. Role of injection laryngoplasty in preventing post-stroke aspiration pneumonia, case series report. Medicine (Baltimore). 2020 Feb;99(7):e19220.

    Article  Google Scholar 

  52. Chen DW, Price MD, LeMaire SA, Coselli JS, Liou NE, Ongkasuwan J. Early versus late inpatient awake transcervical injection laryngoplasty after thoracic aortic repair. Laryngoscope. 2018;128(1):144–7.

    Article  PubMed  Google Scholar 

  53. Choi N, Won S, Jin H, Kim HJ, Park W, Son YI. Additional injection laryngoplasty for patients with unilateral vocal fold paralysis. Laryngoscope. 2020;130(12):2863–8.

    Article  PubMed  Google Scholar 

  54. Pan S, Sadoughi B. Effectiveness of injection laryngoplasty for aspiration in acute iatrogenic vocal fold paralysis: a systematic review. Laryngoscope. 2020; https://doi.org/10.1002/lary.29326.

  55. Frontera WR, Hughes VA, Fielding RA, Fiatarone MA, Evans WJ, Roubenoff R. Aging of skeletal muscle: a 12-yr longitudinal study. J Appl Physiol. 2000;88(4):1321–6.

    Article  CAS  PubMed  Google Scholar 

  56. Nair KS. Aging muscle. Am J Clin Nutr. 2005;81(5):953–63.

    Article  CAS  PubMed  Google Scholar 

  57. Thomas LB, Harrison AL, Stemple JC. Aging thyroarytenoid and limb skeletal muscle: lessons in contrast. J Voice. 2008;22(4):430–50.

    Article  PubMed  Google Scholar 

  58. Davids T, Klein AM, Johns MM III. Current dysphonia trends in patients over the age of 65: is vocal atrophy becoming more prevalent? Laryngoscope. 2012;122(2):332–5.

    Article  PubMed  Google Scholar 

  59. Marino JP, Johns MM III. The epidemiology of dysphonia in the aging population. Curr Opin Otolaryngol Head Neck Surg. 2014;22(6):455–9.

    Article  PubMed  Google Scholar 

  60. Ziade G, Semaan S, Fakhri G, El Natout T, Hamdan AL. Thyroarytenoid muscle uptake and attenuation in PET/CT in elderly. Eur Arch Otorhinolaryngol. 2016;273(12):4385–9.

    Article  PubMed  Google Scholar 

  61. Wehrli NE, Bural G, Houseni M, Alkhawaldeh K, Alavi A, Torigian DA. Determination of age-related changes in structure and function of skin, adipose tissue, and skeletal muscle with computed tomography, magnetic resonance imaging, and positron emission tomography. Semin Nucl Med. 2007;37(3):195–205.

    Article  PubMed  Google Scholar 

  62. Sataloff RT, Kost KM, Linville SE. The effects of age on the voice. In: Sataloff RT, editor. Professional voice: the science and art of clinical care. 4th ed. San Diego, CA: Plural Publ; 2017. p. 585–604.

    Google Scholar 

  63. Hamdan AL, Khalifee E, Al Arab N, Asmar K, Hourani R. Volumetric measures of the paralyzed vocal fold using computerized tomography; its clinical implication. Logoped Phoniatr Vocol. 2020:1–5. https://doi.org/10.1080/14015439.2020.1753809.

  64. Mau T, Courey MS. Influence of gender and injection site on vocal fold augmentation. Otolaryngol Head Neck Surg. 2008;138(2):221–5.

    Article  PubMed  Google Scholar 

  65. Butler JE, Hammond TH, Gray SD. Gender-related differences of hyaluronic acid distribution in the human vocal fold. Laryngoscope. 2001;111(5):907–11.

    Article  CAS  PubMed  Google Scholar 

  66. Roy N, Merrill RM, Gray SD, Smith EM. Voice disorders in the general population: prevalence, risk factors, and occupational impact. Laryngoscope. 2005;115(11):1988–95.

    Article  PubMed  Google Scholar 

  67. Lin WY, Chang WD, Ko LW, Tsou YA, Chen SH. Impact of patient-related factors on successful autologous fat injection laryngoplasty in thyroid surgical treated related unilateral vocal fold paralysis-observational study. Medicine (Baltimore). 2020;99(1):e18579.

    Article  Google Scholar 

  68. Fang TJ, Pei YC, Li HY, Wong AM, Chiang HC. Glottal gap as an early predictor for permanent laryngoplasty in unilateral vocal fold paralysis. Laryngoscope. 2014;124(9):2125–30.

    Article  PubMed  Google Scholar 

  69. Pearson JJ, Ortiz AS, Montelongo S, Montelongo S, Simpson B, Guda T, Dion GR. Quantification of injection force mechanics during injection laryngoplasty. Laryngoscope. 2019;129(5):1060–6.

    Article  CAS  PubMed  Google Scholar 

  70. Lisi C, Hawkshaw MJ, Sataloff RT. Viscosity of materials for laryngeal injection: a review of current knowledge and clinical implications. J Voice. 2013;27(1):119–23.

    Article  PubMed  Google Scholar 

  71. Dang JH, Liou NE, Ongkasuwan J. Anticoagulation and antiplatelet therapy in awake transcervical injection laryngoplasty. Laryngoscope. 2017;127(8):1850–4.

    Article  CAS  PubMed  Google Scholar 

  72. Sakai N, Takizawa M, Furuta Y, Kumagai M, Anadolu YR, Inuyama Y. Histological study of atelocollagen infused into the human vocal cords. Auris Nasus Larynx. 1991;18(1):61–5.

    Article  CAS  PubMed  Google Scholar 

  73. "CYMETRA® Micronized AlloDerm® Tissue". WoundReference. https://woundreference.com/app/topic?id=cymetra-micronized-alloderm-tissue. 2018; Accessed Mar 2021.

  74. Courey MS. Homologous collagen substances for vocal fold augmentation. Laryngoscope. 2001;111(5):747–58.

    Article  CAS  PubMed  Google Scholar 

  75. Remacle M, Marbaix E, Bertrand B, Hamoir M, van den Eeckhaut J. Correction of glottic insufficiency by collagen injection. Ann Otol Rhinol Laryngol. 1990;99(6):438–44.

    Article  CAS  PubMed  Google Scholar 

  76. Anderson TD, Sataloff RT. Complications of collagen injection of the vocal fold: report of several unusual cases and review of the literature. J Voice. 2004;18(3):392–7.

    Article  PubMed  Google Scholar 

  77. Mikaelian DO, Lowry LD, Sataloff RT. Lipoinjection for unilateral vocal cord paralysis. Laryngoscope. 1991;101(5):465–8.

    Article  CAS  PubMed  Google Scholar 

  78. Elbadan HE, Hussein WK, Elmaghraby RM. Transcervical fat injection laryngoplasty for unilateral vocal fold paralysis: an easy way to do the job. Eur Arch Otorhinolaryngol. 2017;274(12):4161–7.

    Article  PubMed  Google Scholar 

  79. Hsiung MW, Woo P, Minasian A, Schaefer MJ. Fat augmentation for glottic insufficiency. Laryngoscope. 2000;110(6):1026–33.

    Article  CAS  PubMed  Google Scholar 

  80. Shindo ML, Zaretsky LS, Rice DH. Autologous fat injection for unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol. 1996;105(8):602–6.

    Article  CAS  PubMed  Google Scholar 

  81. DeFatta RA, DeFatta RJ, Sataloff RT. Laryngeal lipotransfer: review of a 14-year experience. J Voice. 2013;27(4):512–5.

    Article  PubMed  Google Scholar 

  82. Truzzi GM, Pauna HF, Bette P, Gusmao RJ, Crespo AN, Semenzati GO. Methods of fat tissue processing for human vocal fold injection: a systematic review. J Voice. 2017;31(2):244.e17–21.

    Article  Google Scholar 

  83. Rinker BD, Vyas KS. Do stem cells have an effect when we fat graft? Ann Plast Surg. 2016;76(S4):S359–63.

    Article  CAS  PubMed  Google Scholar 

  84. McCulloch TM, Andrews BT, Hoffman HT, Graham SM, Karnell MP, Minnick C. Long-term follow-up of fat injection laryngoplasty for unilateral vocal cord paralysis. Laryngoscope. 2002;112(7):1235–8.

    Article  PubMed  Google Scholar 

  85. Laccourreye O, Papon JF, Kania R, Crevier-Buchman L, Brasnu D, Hans S. Intracordal injection of autologous fat in patients with unilateral laryngeal nerve paralysis: long-term results from the patient's perspective. Laryngoscope. 2003;113(3):541–5. (SAME AS 79).

    Article  PubMed  Google Scholar 

  86. Umeno H, Shirouzu H, Chitose SI, Nakashima T. Analysis of voice function following autologous fat injection for vocal fold paralysis. Otolaryngol Head Neck Surg. 2005;132(1):103–7.

    Article  PubMed  Google Scholar 

  87. Fang TJ, Li HY, Gliklich RE, Chen YH, Wang PC, Chuang HF. Outcomes of fat injection laryngoplasty in unilateral vocal cord paralysis. Arch Otolaryngol Head Neck Surg. 2010;136(5):457–62.

    Article  PubMed  Google Scholar 

  88. Chheda NN, Rosen CA, Belafsky PC, Simpson CB, Postma GN. Revision laryngeal surgery for the suboptimal injection of calcium hydroxylapatite. Laryngoscope. 2008;118(12):2260–3.

    Article  CAS  PubMed  Google Scholar 

  89. DeFatta RA, Chowdhury FR, Sataloff RT. Complications of injection laryngoplasty using calcium hydroxylapatite. J Voice. 2012;26(5):614–8.

    Article  PubMed  Google Scholar 

  90. Lee M, Lee DY, Kwon TK. Safety of office-based percutaneous injection laryngoplasty with calcium hydroxylapatite. Laryngoscope. 2019;129(10):2361–5.

    Article  CAS  PubMed  Google Scholar 

  91. Wang C, Wu S, Tu Y, Liu S. Hyaluronic acid injection laryngoplasty for unilateral vocal fold paralysis- a systematic review and meta-analysis. Cell. 2020;9(11):2417.

    Article  CAS  Google Scholar 

  92. King JM, Simpson CB. Modern injection augmentation for glottic insufficiency. Curr Opin Otolaryngol Head Neck Surg. 2007;15(3):153–8.

    Article  PubMed  Google Scholar 

  93. Hertegård S, Hallén L, Laurent C, et al. Cross-linked hyaluronan versus collagen for injection treatment of glottal insufficiency: 2-year follow-up. Acta Otolaryngol. 2004;124(10):1208–14.

    Article  PubMed  CAS  Google Scholar 

  94. Hertegård S, Hallén L, Laurent C, et al. Cross-linked hyaluronan used as augmentation substance for treatment of glottal insufficiency: safety aspects and vocal fold function. Laryngoscope. 2002;112(12):2211–9.

    Article  PubMed  Google Scholar 

  95. Song PC, Sung CK, Franco RA Jr. Voice outcomes after endoscopic injection laryngoplasty with hyaluronic acid stabilized gel. Laryngoscope. 2010;120 Suppl 4:S199.

    Article  PubMed  Google Scholar 

  96. Rudolf R, Sibylle B. Laryngoplasty with hyaluronic acid in patients with unilateral vocal fold paralysis. J Voice. 2012;26(6):785–91.

    Article  PubMed  Google Scholar 

  97. Shamanna SG, Bosch JD. Injection laryngoplasty: a serious reaction to hyaluronic acid. J Otolaryngol Head Neck Surg. 2011;40(5):E39–42.

    PubMed  Google Scholar 

  98. Dominguez LM, Tibbetts KM, Simpson CB. Inflammatory reaction to hyaluronic acid: a newly described complication in vocal fold augmentation. Laryngoscope. 2017;127(2):445–9.

    Article  CAS  PubMed  Google Scholar 

  99. Hamdan AL, Khalifee E. Adverse reaction to restylane: a review of 63 cases of injection laryngoplasty. Ear Nose Throat J. 2019;98(4):212–6.

    Article  PubMed  Google Scholar 

  100. Perazzo PS, de Campos DA, Lancellotti CL. Histological behavior of the vocal fold after hyaluronic acid injection. J Voice. 2009;23(1):95–8.

    Article  PubMed  Google Scholar 

  101. Lee BJ, Wang SG, Goh EK, Chon KM, Lee CH. Intracordal injection of autologous auricular cartilage in the paralyzed canine vocal fold. Otolaryngol Head Neck Surg. 2004;131(1):34–43.

    Article  PubMed  Google Scholar 

  102. Lim YS, Lee YS, Lee JC, et al. Intracordal auricular cartilage injection for unilateral vocal fold paralysis. J Biomed Mater Res B Appl Biomater. 2015;103(1):47–51.

    Article  PubMed  CAS  Google Scholar 

  103. Hong SJ, Lee SH, Jin SM, et al. Plasma gel as a new augmentation material for injection laryngoplasty in rabbit model: histologic analysis. Otolaryngol Head Neck Surg. 2013;149(4):596–602.

    Article  PubMed  Google Scholar 

  104. Woo SH, Kim JP, Park JJ, Chung PS, Lee SH, Jeong HS. Autologous platelet-poor plasma gel for injection laryngoplasty. Yonsei Med J. 2013;54(6):1516.

    Article  PubMed  PubMed Central  Google Scholar 

  105. de Souza FC, Olival-Costa H, da Silva L, Pontes PA, Lancellotti CL. Bacterial cellulose as laryngeal medialization material: an experimental study. J Voice. 2011;25(6):765–9.

    Article  PubMed  Google Scholar 

  106. Sataloff RT. Voice surgery. In: Sataloff RT, editor. Professional voice: the science and art of clinical care. 4th ed. San Diego, CA: Plural Publishing; 2017. p. 1371–478.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Otolaryngology, Head & Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon

    Abdul-latif Hamdan

  2. Department of Otolaryngology Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, PA, USA

    Abdul-latif Hamdan

  3. Otolaryngology – Head and Neck Surgery, Drexel University, Philadelphia, PA, USA

    Robert Thayer Sataloff & Mary J. Hawkshaw

Authors
  1. Abdul-latif Hamdan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert Thayer Sataloff
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mary J. Hawkshaw
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Abdul-latif Hamdan .

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Hamdan, Al., Sataloff, R.T., Hawkshaw, M.J. (2022). Office-Based Injection Laryngoplasty. In: Office-Based Laryngeal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-91936-8_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-91936-8_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-91935-1

  • Online ISBN: 978-3-030-91936-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation