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Oral Cancer Management

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Peterson’s Principles of Oral and Maxillofacial Surgery

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Abstract

Worldwide, head and neck cancer accounts for approximately 650,000 new patients diagnosed annually and results in more than 330,000 deaths every year. In the United States, head and neck cancer makes up roughly 3% of malignancies, with approximately 53,000 new cases per year and with 10,800 dying from the disease annually (Bray et al. CA Cancer J Clin 68:394, 2018). Greater than 90% of these cancers are squamous cell carcinomas that arise from the oral cavity, oropharynx, and larynx. Oral cavity makes up 30% of these head and neck cancers. As healthcare professionals and specialists in the oral and maxillofacial region, it is imperative that we be well versed, and if not, at least familiar with the etiology, diagnosis, classification, and staging of oral cancer as presented in ► Chap. 32, and as well with the management and treatment of oral cancer presented in this chapter. This chapter will review the management of premalignant lesions and chemoprevention, treatment planning for oral cancer, and multimodality treatment including surgery, radiation therapy, chemotherapy, and immunotherapy. Special considerations for cancer of each individual subsite of the oral cavity will also be discussed in addition to management of both the N0 and N+ neck. Lastly, follow-up surveillance for recurrence and second primary cancers, and future therapies will be reviewed.

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Authors and Affiliations

  1. LSU Health Shreveport, Department of Oral & Maxillofacial Surgery/Head & Neck Surgery, Shreveport, LA, USA

    Andrew T. Meram

  2. UCSF Fresno, Department of Oral & Maxillofacial Surgery, Fresno, CA, USA

    Brian M. Woo

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Editors and Affiliations

  1. College of Dentistry, University of Illinois, Chicago, IL, USA

    Michael Miloro

  2. Department of Oral & Maxillofacial Surgery, Louisiana State University Health Science, Shreveport, LA, USA

    G. E. Ghali

  3. Oral and Maxillofacial Surgery, The Ohio State University, Columbus, OH, USA

    Peter E. Larsen

  4. Department of Oral and Maxillofacial Surgery, University of Alabama at Birmingham School of Dentistry and Medicine, Birmingham, AL, USA

    Peter Waite

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Meram, A.T., Woo, B.M. (2022). Oral Cancer Management. In: Miloro, M., Ghali, G.E., Larsen, P.E., Waite, P. (eds) Peterson’s Principles of Oral and Maxillofacial Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-91920-7_34

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