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Fungi in Pharmaceuticals and Production of Antibiotics

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Applied Mycology

Part of the book series: Fungal Biology ((FUNGBIO))

Abstract

The pharmaceutical industry develops, manufactures, and markets medicines and drugs, and is an indispensable part of healthcare sectors. Millions of patients with life-threatening diseases are treated each year with medicines made by fungi, a mostly understudied group of immense commercial importance. The discovery of the treasure trove of fungal secondary metabolites like antibiotics, cholesterol-lowering drug, etc. intrigues the determination of the chemical potential of fungal strains and adoption of new strategies to awake the associated biosynthetic genes. Fungal existence in diverse types of habitat provides them the ability of developing various types of survival mechanism, and these properties make them a rich resource for being used in pharmaceutical industries. The relatively easier mechanism of cultivation and extraction of products made the fungi an important and nonexpensive source for the industries for developing medicinal drugs. The unique bioactive ingredients and their derivatives have attracted researchers for the development of new antibiotics effective against common bacterial diseases and various biofilm-associated chronic infections. This chapter would focus predominantly on the analysis of pharmaceutical competence of fungi, cultivation-based and genetic engineering-based methods, and their applicability for human welfare.

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Authors and Affiliations

  1. Department of Biotechnology, Maulana Abul Kalam Azad University of Technology, Haringhata, West Bengal, India

    Bandita Dutta & Ankita Dey

  2. Department of Biotechnology, University of Engineering & Management, Kolkata, West Bengal, India

    Dibyajit Lahiri & Moupriya Nag

  3. Department of Microbiology, School of Science, RK University, Rajkot, Gujarat, India

    Sougata Ghosh & Rina Rani Ray

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  2. Dibyajit Lahiri
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  3. Moupriya Nag
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  4. Sougata Ghosh
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  5. Ankita Dey
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  6. Rina Rani Ray
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  1. Department of Botany, University of Lucknow, Lucknow, Uttar Pradesh, India

    Amritesh Chandra Shukla

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Dutta, B., Lahiri, D., Nag, M., Ghosh, S., Dey, A., Ray, R.R. (2022). Fungi in Pharmaceuticals and Production of Antibiotics. In: Shukla, A.C. (eds) Applied Mycology. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-030-90649-8_11

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