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New Insights in Spermatogonial Stem Cells

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Stem Cells in Reproductive Tissues and Organs

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL,volume 70))

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Abbreviations

ACVR1B:

Activin A receptor type 1B

ACVR2B:

Activin A receptor type 2B

AdVac:

A-dark spermatogonium with nuclear dilution zone

AdNoVac:

A-dark spermatogonium without nuclear vacuole

AMBRA1:

Autophagy and beclin 1 regulator 1

ALDOA:

Aldolase, fructose-bisphosphate A

BAMBI:

BMP and activin membrane-bound inhibitor

BCL2:

BCL2 apoptosis regulator

BMPR1B:

Bone morphogenetic protein receptor type 1B

C3orf22:

Chromosome 3 open reading frame 22

CADH1:

Cadherin 1 (CDH1)

CD:

Cluster of differentiation

CD9:

CD9 molecule

CDK:

Cyclin-dependent kinase

CELF4:

CUGBP Elav-like family member 4

C-MYC:

C-MYC proto-oncogene, BHLH transcription factor

COL1A2:

Collagen type I alpha 2 chain

DA:

Dopamine, dopaminergic neurons

DAZL:

Deleted in azoospermia like

DCAF4L1:

DDB1 and CUL4 associated factor 4 like 1

DDX4:

DEAD-box helicase 4 (VASA)

DEG:

Differentially expressed genes

DMRT1:

Doublesex and mab-3-related transcription factor 1

DOCK8:

Dedicator of cytokinesis 8

DUSP6:

Dual specificity phosphatase 6

DVL1:

Dishevelled segment polarity protein 1

EDNRA:

Endothelin receptor type A

EGC:

Embryonic germ cell

EGR4:

Early growth response 4

EIF2:

Eukaryotic translation initiation factor 2

EIF4B:

Eukaryotic translation initiation factor 4B

EIF4E:

Eukaryotic translation initiation factor 4E

EIF4EBP1:

Eukaryotic translation initiation factor 4E-binding protein 1

ELAVL2:

ELAV-like RNA binding protein 2

ENO2:

Enolase 2

ENO3:

Enolase 3

EOMES:

Eomesodermin

EPHA2:

EPH receptor A2

ESC:

Embryonic stem cell

ETV5:

ETS variant transcription factor 5

FACS:

Fluorescence-activated cell sorting

FGF:

Fibroblast growth factor

FGFR3:

Fibroblast growth factor receptor 3

FSD1:

Fibronectin type III and SPRY domain containing 1

Fibs:

Fibroblast

FSHR:

Follicle-stimulating hormone receptor

FST:

Follistatin

GAD1:

Glutamate decarboxylase 1

GATA4:

GATA binding protein 4

GDF3:

Growth differentiation factor

GDNF:

Glial cell-derived neurotrophic factor

GFP:

Green fluorescent protein

GFRA1:

GDNF family receptor alpha 1

GiPSC:

GSCs-derived iPSC

GPR125:

Adhesion G protein-coupled receptor A3 (ADGRA3)

GSC:

Germ stem cell

h:

Human

haGSC:

Human adult germ stem cell

hFibs:

Human fibroblasts

ICA1L:

Islet cell autoantigen 1 like

ID4:

Inhibitor of DNA binding 4, HLH protein

INTGA6:

Integrin A6

iPSC:

Induced pluripotent stem cell

KIT:

KIT proto-oncogene, receptor tyrosine kinase

KLF4:

Kruppel-like factor 4

KLF6:

Kruppel-like factor 6

LATS2:

Large tumor suppressor kinase 2

L1TD1:

LINE1-type transposase domain containing 1

LIF:

Leukemia inhibitory factor

LIN28:

Lin-28 homolog A

LPPR3:

Phospholipid phosphatase-related 3

LY6K:

Lymphocyte antigen 6 family member K

MACS:

Magnetic-activated cell sorting

MAGEA4:

MAGE family member A4

MAGEC1:

MAGE family member C1

MCM7:

Minichromosome maintenance complex component 7

MEF:

Mouse embryonic fibroblast

MKI67:

Marker of proliferation Ki-67

MLST8:

MTOR-associated protein, LST8 homolog

mRNA:

Messenger ribonucleic acid

MSC:

Mesenchymal stem cell

mTOR:

Mechanistic/mammalian target of rapamycin kinase

NANOG:

Nanog homeobox

NANOS2:

Nanos C2HC-type zinc finger 2

NANOS3:

Nanos C2HC-type zinc finger 3

NOG:

Noggin

OCT4:

Octamer-binding transcription factor 4

p21:

Cyclin-dependent kinase inhibitor 1

p53:

Tumor protein P53

PABPC1:

Poly(A) binding protein cytoplasmic 1

PASD1:

PAS domain-containing repressor 1

PAX7:

Paired box 7

PDGFRA:

Platelet-derived growth factor receptor alpha

PFKL:

Phosphofructokinase, liver type

PGC:

Primordial germ cell

PHGDH:

Phosphoglycerate dehydrogenase

PIWIL4:

Piwi-like RNA-mediated gene silencing 4

PLZF:

Zinc finger and BTB domain containing 16 (ZBTB16)

POU5F1:

POU class 5 homeobox 1

PPP1R36:

Protein phosphatase 1 regulatory subunit 36

PPRC1:

PPARG-related coactivator 1

PTPN13:

Protein tyrosine phosphatase non-receptor type 13

PVR:

PVR cell adhesion molecule

RA:

Retinoic acid

RHOX10:

Rhox homeobox family member 10

RHOX13:

Rhox homeobox family member 13

RHOXF1:

Rhox homeobox family member 1

RNA:

Ribonucleic acid

RNAi:

Ribonucleic acid interference

RPTOR:

Regulatory-associated protein of MTOR complex 1

RT-PCR:

Reverse transcription polymerase chain reaction

SAGE1:

Sarcoma antigen 1

SALL4:

Spalt-like transcription factor 4

SCF:

Stem cell factor

SCOS:

Sertoli-cell-only-syndrome

scRNA:

Small conditional RNA

scRNA-seq:

Single-cell RNA sequencing

SERINC2:

Serine incorporator 2

SIX1:

SIX homeobox 1

SOX2:

SRY-box transcription factor 2

SPATS2L:

Spermatogenesis-associated serine-rich 2 like

SPG:

Spermatogonium, spermatogonia

SSC:

Spermatogonial stem cell

SSEA1:

Stage-specific embryonic antigen-1

SSEA4:

Stage-specific embryonic antigen-4

ST3GAL2:

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

STRA8:

Stimulated by retinoic acid 8

SUSD2:

Sushi domain containing 2

SV40T:

SV40 large T antigen

TAZ:

Tafazzi

TCF3:

Transcription factor 3

TCL1:

TCL1 family AKT coactivator

TCN1:

Transcobalamin 1

TCN2:

Transcobalamin 2

TERT:

Telomerase reverse transcriptase

TEX15:

Testis expressed 15, meiosis and synapsis associated

TGFA:

Transforming growth factor alpha

TGFBR:

Transforming growth factor beta receptor

TIMP2:

TIMP metallopeptidase inhibitor 2

TOP2A:

DNA topoisomerase II alpha

TPI1:

Triosephosphate isomerase 1

TRA-1-60:

 T cell receptor alpha locus

TRA-1-81:

 T cell receptor alpha locus

TSPAN8:

Tetraspanin 8

TSPAN33:

Tetraspanin 33

TPH1:

Tryptophan hydroxylase 1

TRP53:

Tumor protein P53

TSPYL1:

Testis-specific Y-encoded-like protein 1

TTC14:

Tetratricopeptide repeat domain 14

UCHL1:

Ubiquitin C-terminal hydrolase L1

USF3:

Upstream transcription factor family member 3

UTF1:

Undifferentiated embryonic cell transcription factor 1

VASA:

Vasa homolog (DDX4)

ZBTB16:

Zinc finger and BTB domain containing 16

ZBTB33:

Zinc finger and BTB domain containing 33

ZFHX3:

Zinc finger homeobox 3

ZNF654:

Zinc finger protein 654

YAP:

Yes1-associated transcriptional regulator

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None of the authors have any conflicts of interest to disclose, and all authors support the submission to this book.

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    Sabine Conrad

  2. Faculty of Biotechnology, Amol University of Special Modern Technologies, Amol, Iran

    Hossein Azizi

  3. Medical Faculty, Institute for Anatomy and Cell Biology, University of Heidelberg, INF 307, 69120, Heidelberg, Germany

    Mehdi Amirian, Maryam Hatami & Thomas Skutella

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    Irma Virant-Klun

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Conrad, S., Azizi, H., Amirian, M., Hatami, M., Skutella, T. (2022). New Insights in Spermatogonial Stem Cells. In: Virant-Klun, I. (eds) Stem Cells in Reproductive Tissues and Organs. Stem Cell Biology and Regenerative Medicine, vol 70. Humana, Cham. https://doi.org/10.1007/978-3-030-90111-0_6

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