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Management of COVID-19 in the Intensive Care Unit

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References

  • Alhazzani W, Møller MH, Arabi YM et al (2019) Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19). Crit Care Med.

    Google Scholar 

  • ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT et al (2012) Acute respiratory distress syndrome: the Berlin Definition. JAMA. 307(23):2526–2533

    Google Scholar 

  • Cai Q, Yang M, Liu D et al (2020) Experimental treatment with favipiravir for COVID-19: an open-label control study. Engineering (Beijing). https://doi.org/10.1016/j.eng.2020.03.007

  • Ding L, Wang L, Ma W et al (2020) Efficacy and safety of early prone positioning combined with HFNC or NIV in moderate to severe ARDS: a multi-center prospective cohort study. Crit Care 24:28

    Article  Google Scholar 

  • Gautret P, Lagier JC, Parola P et al (2020) Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents. 2020:105949

    Article  Google Scholar 

  • Grasselli G, Zangrillo A, Zanella A et al (2020) Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA. 323(16):1574–1581

    Article  CAS  Google Scholar 

  • Guan WJ, Ni ZY, Hu Y et al (2020) Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. published online Feb 28

    Google Scholar 

  • Huang BH, Wu CH, Hsia CP, Yin Chen C (2007) Azithromycin-induced torsade de pointes. Pacing Clin Electrophysiol 30:1579–1582

    Article  Google Scholar 

  • Huang C, Wang Y, Li X et al (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 395(10223):497–506

    Article  CAS  Google Scholar 

  • Inci K (2020) Safe intrahospital transport of critically ill COVID-19 patients. J Crit Intensive Care 11(Suppl. 1):18–19

    Google Scholar 

  • Li L, Zhang W, Hu Y et al (2020) Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial. JAMA. https://doi.org/10.1001/jama.2020.10044

  • Martins IJ (2020) COVID-19 infection and anti-aging gene inactivation. Acta Scientific Nutritional Health 4(5):01–02

    Article  Google Scholar 

  • Mehta P, McAuley DF, Brown M et al (2020) COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 395(10229):1033–1034

    Article  CAS  Google Scholar 

  • Morgan ND, Patel SV, Dvorkina O (2013) Suspected hydroxychloroquine-associated QT-interval prolongation in a patient with systemic lupus erythematosus. J Clin Rheumatol 19:286–288

    Article  Google Scholar 

  • National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wiedemann HP, Wheeler AP et al (2006) Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 354(24):2564–2575

    Article  Google Scholar 

  • Pan C, Chen L, Lu C et al (2020) Lung recruitability in COVID-19-associated acute respiratory distress syndrome: a single-center observational study. Am J Respir Crit Care Med. 201(10):1294–1297

    Article  CAS  Google Scholar 

  • Peng QY, Wang XT, Zhang LN (2020) Chinese Critical Care Ultrasound Study Group (CCUSG). Findings of lung ultrasonography of novel coronavirus pneumonia during the 2019–2020 epidemic. Intensive Care Med. 46(5):849–850

    Article  CAS  Google Scholar 

  • Phua J, Weng L, Ling L et al (2020) Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. Lancet Respir Med. 8(5):506–517

    Article  CAS  Google Scholar 

  • Ranucci M, Ballotta A, Di Dedda U et al (2020) The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome. J Thromb Haemost. https://doi.org/10.1111/jth.14854

  • Richardson S, Hirsch JS, Narasimhan M et al (2020) Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 323(20):2052–2059

    Article  CAS  Google Scholar 

  • Schünemann HJ, Khabsa J, Solo K et al (2020) Ventilation techniques and risk for transmission of coronavirus disease, including COVID-19: a living systematic review of multiple streams of evidence. Ann Intern Med 173(3):204–216. https://doi.org/10.7326/M20-2306

    Article  PubMed  Google Scholar 

  • Sud S, Friedrich JO, Taccone P et al (2010) Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med. 36(4):585–599

    Article  Google Scholar 

  • Wang D, Hu B, Hu C et al (2020a) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 323(11):1061–1069

    Article  CAS  Google Scholar 

  • Wang M, Cao R, Zhang L et al (2020b) Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 30(3):269–271

    Article  CAS  Google Scholar 

  • Wu Z, McGoogan JM (2020) Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 Cases from the Chinese Center for Disease Control and Prevention. JAMA. https://doi.org/10.1001/jama.2020.2648

  • Yang X, Yu Y, Xu J et al (2020) Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 8(5):475–481

    Article  CAS  Google Scholar 

  • Yao X, Ye F, Zhang M et al (2020) Vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clin Infect Dis:ciaa237

    Google Scholar 

  • Zhou F, Yu T, Du R et al (2020) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 395(10229):1054–1062

    Article  CAS  Google Scholar 

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Acknowledgment

The authors thank all the healthcare professionals who died during the fight against the corona pandemic worldwide.

Funding

This work was not supported financially by any institution or organization.

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (Ethical Committees of the Yıldırım Beyazıt University) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Ağababaoğlu, İ., İnci, K. (2021). Management of COVID-19 in the Intensive Care Unit. In: Asea, A.A.A., Kaur, P. (eds) Coronavirus Therapeutics – Volume II. Advances in Experimental Medicine and Biology, vol 1353. Springer, Cham. https://doi.org/10.1007/978-3-030-85113-2_5

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