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Origin and Structural Biology of Novel Coronavirus (SARS-CoV-2)

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Coronavirus Therapeutics – Volume I

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Abbreviations

AA:

amino acid

ACE2:

Angiotensin-converting enzyme 2

COVID-19:

Coronavirus disease 2019

E:

Envelope protein

FAO:

Food and Agriculture Organization of the United Nations

FP:

Fusion peptide

HR1/2:

Heptad repeat 1/2

IFP:

Internal fusion peptide

IFN:

Interferon

LFA-1:

Lymphocyte function-associated antigen 1

M:

Membrane protein

MERS-CoV:

Middle East respiratory syndrome-related coronavirus

NSP:

Non-structural protein

NF-κB:

Nuclear factor-kappa B

NLRP:

NOD-like receptor

NTD:

N-terminal domain

N:

Nucleocapsid protein

ORF:

Open reading frame

RBD:

Receptor binding domain

SP:

Signal peptide

S:

Spike protein

SARS-CoV:

Severe acute respiratory syndrome-related coronavirus

SARS-CoV-2:

Severe acute respiratory syndrome-related coronavirus 2

TD:

Transmembrane domain

WHO:

World Health Organization

2019-nCoV:

2019-novel coronavirus

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Acknowledgment

This study was supported in part by the Faculty of Medicine, University of Oslo.

Conflict of Interest

The authors report no conflict of interest.

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Correspondence to Asim K. Duttaroy .

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© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Mallick, R., Duttaroy, A.K. (2021). Origin and Structural Biology of Novel Coronavirus (SARS-CoV-2). In: Asea, A.A.A., Kaur, P. (eds) Coronavirus Therapeutics – Volume I. Advances in Experimental Medicine and Biology, vol 1352. Springer, Cham. https://doi.org/10.1007/978-3-030-85109-5_1

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