Skip to main content

Circadian Rhythm Sleep-Wake Disorders: An Overview

  • Chapter
  • First Online:
Sleep Medicine and Physical Therapy

Abstract

The sleep-wake cycle is an example of a biological rhythm that is considered circadian. Understanding these rhythms and monitoring them are important not only to understand their functions but also to describe the occurrence of various diseases from a circadian nature. The control of circadian rhythms presents components of internal and external temporal order. Both influence the consolidation of sleep and waking episodes – essential for restorative sleep, as well as for the homeostatic functioning of all other organic systems. The objective of this chapter is to provide an overview of the pathophysiology, characteristics, and clinical approaches of circadian rhythm disorders with an emphasis on the sleep-wake cycle.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Menna-Barreto L, Wey D. Ontogênese do sistema de temporização: a construção e as reformas dos ritmos biológicos ao longo da vida humana. Psicológica. 2007;18:133–53.

    Google Scholar 

  2. Potter GD, et al. Circadian rhythm and sleep disruption: causes, metabolic consequences, and countermeasures. Endocr Rev. 2016;37(6):584–608.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Dibner C, Schibler U, Albrecht U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol. 2010;72:517–49.

    Article  CAS  PubMed  Google Scholar 

  4. Patke A, Young MW, Axelrod S. Molecular mechanisms and physiological importance of circadian rhythms. Nat Rev Mol Cell Biol. 2020;21(2):67–84.

    Article  CAS  PubMed  Google Scholar 

  5. Brown AJ, Pendergast JS, Yamazaki S. Peripheral circadian oscillators. Yale J Biol Med. 2019;92(2):327–35.

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Dijk DJ, Czeisler CA. Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans. Neurosci Lett. 1994;166(1):63–8.

    Article  CAS  PubMed  Google Scholar 

  7. Skene DJ, Arendt J. Human circadian rhythms: physiological and therapeutic relevance of light and melatonin. Ann Clin Biochem. 2006;43(Pt 5):344–53.

    Article  CAS  PubMed  Google Scholar 

  8. Ulhoa MA, et al. When does stress end? Evidence of a prolonged stress reaction in shiftworking truck drivers. Chronobiol Int. 2011;28(9):810–8.

    Article  PubMed  Google Scholar 

  9. Haus E, Smolensky M. Biological clocks and shift work: circadian dysregulation and potential long-term effects. Cancer Causes Control. 2006;17(4):489–500.

    Article  PubMed  Google Scholar 

  10. Smolensky MH, et al. Clinical chronobiology and chronotherapeutics with applications to asthma. Chronobiol Int. 1999;16(5):539–63.

    Article  CAS  PubMed  Google Scholar 

  11. AASM, International Classification of Sleep Disorders (ICSD-3). 3rd ed. 2014; American Academy of Sleep Medicine.

    Google Scholar 

  12. Lu BS, Zee PC. Circadian rhythm sleep disorders. Chest. 2006;130(6):1915–23.

    Article  PubMed  Google Scholar 

  13. Auger RR, et al. Clinical practice guideline for the treatment of intrinsic circadian rhythm sleep-wake disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An update for 2015: an american academy of sleep medicine clinical practice guideline. J Clin Sleep Med. 2015;11(10):1199–236.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Peixoto CA, et al. Adolescents living in homes without electric lighting have earlier sleep times. Behav Sleep Med. 2009;7(2):73–80.

    Article  PubMed  Google Scholar 

  15. Wittmann M, et al. Social jetlag: misalignment of biological and social time. Chronobiol Int. 2006;23(1–2):497–509.

    Article  PubMed  Google Scholar 

  16. Karlsson BH, et al. Metabolic disturbances in male workers with rotating three-shift work. Results of the WOLF study. Int Arch Occup Environ Health. 2003;76(6):424–30.

    Article  PubMed  Google Scholar 

  17. Lindstrom M, Malmo G. Shoulder-neck study, psychosocial work conditions, social participation and social capital: a causal pathway investigated in a longitudinal study. Soc Sci Med. 2006;62(2):280–91.

    Article  PubMed  Google Scholar 

  18. Costa G. Shift work and occupational medicine: an overview. Occup Med (Lond). 2003;53(2):83–8.

    Article  PubMed  Google Scholar 

  19. Glina DMR, ROCHA LE. Prevenção para a saúde mental no trabalho. In: Saúde Mental no Trabalho: Desafios e Soluções. São Paulo: Editora VK; 2000. p. 17–52.

    Google Scholar 

  20. Harma M, Kompier MA, Vahtera J. Work-related stress and health--risks, mechanisms and countermeasures. Scand J Work Environ Health. 2006;32(6):413–9.

    Article  PubMed  Google Scholar 

  21. Chida Y, Steptoe A. Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis. Biol Psychol. 2009;80(3):265–78.

    Article  PubMed  Google Scholar 

  22. Akerstedt T. Work hours, sleepiness and the underlying mechanisms. J Sleep Res. 1995;4(S2):15–22.

    Article  CAS  PubMed  Google Scholar 

  23. Wyatt J. Overview of circadian sleep-wake rhythm disorders. Post TW UpToDate. 2020.

    Google Scholar 

  24. Lewy AJ, Sack RL. The dim light melatonin onset as a marker for circadian phase position. Chronobiol Int. 1989;6(1):93–102.

    Article  CAS  PubMed  Google Scholar 

  25. Burgess HJ, et al. Home dim light melatonin onsets with measures of compliance in delayed sleep phase disorder. J Sleep Res. 2016;25(3):314–7.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Ulhôa, M.A., Moreno, C.R.C. (2022). Circadian Rhythm Sleep-Wake Disorders: An Overview. In: Frange, C., Coelho, F.M.S. (eds) Sleep Medicine and Physical Therapy. Springer, Cham. https://doi.org/10.1007/978-3-030-85074-6_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-85074-6_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-85073-9

  • Online ISBN: 978-3-030-85074-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics