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Patellar Tendinopathy: Biologics

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Orthobiologics

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Abstract

Patellar tendinopathy is a common cause of anterior knee pain characterized by the degeneration of the proximal patellar tendon. It is often an overuse injury caused by excessive activities that require jumping, running, or rapid changes in direction. The mainstay of treatment for patellar tendinopathy is conservative management, consisting of physical therapy, extracorporeal shock wave therapy, and dry needling. There are multiple studies evaluating the effect of injectable biologics in patients with patellar tendinopathy. Injectable biologics include hyaluronic acid, autologous bone marrow stem/stromal cells, and platelet-rich plasma (PRP). Injectable PRP is the most studied biologic with promising results for the treatment of patellar tendinopathy. The majority of these studies specifically look at the effect of PRP on patellar tendinopathy and the level of evidence ranges from case series to randomized control trials to systematic reviews/meta-analyses. Numerous high-quality studies show improvement in symptoms, and many show a significant improvement compared to other conservative options. There is room for improvement with regard to uniformity of administration protocols, and more high-quality controlled studies are needed to determine its true efficacy.

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Authors and Affiliations

  1. The Orthopedic Group, Leesburg, VA, USA

    Rahman Kandil

  2. Department of Orthopaedic Surgery, University of Colorado, Denver, CO, USA

    Jason Dragoo

Authors
  1. Rahman Kandil
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  2. Jason Dragoo
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Correspondence to Jason Dragoo .

Editor information

Editors and Affiliations

  1. Rizzoli Orthopaedic Institute, Bologna, Italy

    Giuseppe Filardo

  2. Orthopaedic & Sports Medicine Group, Santa Monica Orthopaedic & Sports Medicine, Santa Monica, CA, USA

    Bert R. Mandelbaum

  3. Orthopaedic Surgery and Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA

    George F. Muschler

  4. Hospital for Special Surgery, New York, NY, USA

    Scott A. Rodeo

  5. Institute for Medical Science in Sports, Osaka Health Science University, Osaka, Japan

    Norimasa Nakamura

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Kandil, R., Dragoo, J. (2022). Patellar Tendinopathy: Biologics. In: Filardo, G., Mandelbaum, B.R., Muschler, G.F., Rodeo, S.A., Nakamura, N. (eds) Orthobiologics. Springer, Cham. https://doi.org/10.1007/978-3-030-84744-9_17

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  • DOI: https://doi.org/10.1007/978-3-030-84744-9_17

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-84743-2

  • Online ISBN: 978-3-030-84744-9

  • eBook Packages: MedicineMedicine (R0)

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