Abstract
Breast cancer is the commonest malignancy in women with one in eight women developing this disease during their lifetime. The impact of this very common disease on healthcare systems is enormous, affecting a major part of the population, with significant socioeconomic consequences. During the last decade, we have seen many advances in the treatment of this disease, with the introduction of newer and innovative drugs especially in the metastatic setting. The overall survival rate of this disease has climbed significantly, not only as a result of screening being implemented in many countries, but also because patient awareness of symptoms has increased and research funding and disease understanding have helped to establish earlier diagnosis and better treatment. Despite the better prognosis and survival, this disease can severely compromise the quality of life of the patients and their carers. This chapter will try to analyse the importance of understanding patient and disease characteristics like age, stage and disease heterogeneity, the different treatment pathways, and how this affect differently the quality of life.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ferlay J, Colombet M, Soerjomataram I, Parkin DM, Piñeros M, Znaor A, et al. Cancer statistics for the year 2020: an overview. Int J Cancer. 2021 https://doi.org/10.1002/ijc.33588. Online ahead of print
Rojas K, Stuckey A. Breast cancer epidemiology and risk factors. Clin Obstet Gynecol. 2016;59:651–72.
Holm J, Eriksson L, Ploner A, Eriksson M, Rantalainen M, Li J, et al. Assessment of breast cancer risk factors reveals subtype heterogeneity. Cancer Res. 2017;77:3708–17.
Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence. Lancet. 2019;394:1159–68.
Neibergs H. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Women’s Oncol Rev. 2004;4:59–60.
Liu Y, Nguyen N, Colditz GA. Links between alcohol consumption and breast cancer: a look at the evidence. Womens Health. 2015;11:65–77.
Figueroa JD, Gierach GL, Duggan MA, Fan S, Pfeiffer RM, Wang Y, et al. Risk factors for breast cancer development by tumor characteristics among women with benign breast disease. Breast Cancer Res. 2021;23
Waks AG, Winer EP. Breast cancer treatment: a review. JAMA. 2019;321:288.
Eisen MB, Jeffreyk SS, Rees CA, Pergamenschikov A, Williams C, Botstein D. Molecular portraits of human breast tumours. Nature. 2000;533:747–52.
Campbell-Enns H, Woodgate R. The psychosocial experiences of women with breast cancer across the lifespan: a systematic review protocol. JBI Database System Rev Implement Rep. 2015;13:112–21.
Syrowatka A, Motulsky A, Kurteva S, Hanley JA, Dixon WG, Meguerditchian AN, et al. Predictors of distress in female breast cancer survivors: a systematic review. Breast Cancer Res Treat. 2017;165:229–45.
Miaja M, Platas A, Martinez-Cannon BA. Psychological impact of alterations in sexuality, fertility, & body image in young breast cancer patients & their partners. Revista de Investigacion Clinica. 2017;69:204–9.
Kedde H, Van De Wiel HBM, Weijmar Schultz WCM, Wijsen C. Sexual dysfunction in young women with breast cancer. Support Care Cancer. 2013;21:271–80.
Sharma N, Purkayastha A. Factors affecting quality of life in breast cancer patients: a descriptive and cross-sectional study with review of literature. J Mid-Life Health. 2017;8:75–83.
Mokhatri-Hesari P, Montazeri A. Health-related quality of life in breast cancer patients: review of reviews from 2008 to 2018. Health Qual Life Outcomes. 2020;18:338.
Scotté F, Bossi P, Carola E, Cudennec T, Dielenseger P, Gomes F, et al. Addressing the quality of life needs of older patients with cancer: a SIOG consensus paper and practical guide. Ann Oncol. 2018;29:1718–26.
Valachis A, Tsali L, Pesce LL, Polyzos NP, Dimitriadis C, Tsalis K, et al. Safety of pregnancy after primary breast carcinoma in young women: a meta-analysis to overcome bias of healthy mother effect studies. Obstet Gynecol Surv. 2010;65:786–93.
Deshpande NA, Braun IM, Meyer FL. Impact of fertility preservation counseling and treatment on psychological outcomes among women with cancer: a systematic review. Cancer. 2015;121:3938–47.
Müller V, Nabieva N, Häberle L, Taran FA, Hartkopf AD, Volz B, et al. Impact of disease progression on health-related quality of life in patients with metastatic breast cancer in the PRAEGNANT breast cancer registry. Breast. 2018;37:154–60.
Ng ET, Ang RZ, Tran BX, Ho CS, Zhang Z, Tan W, et al. Comparing quality of life in breast cancer patients who underwent mastectomy versus breast-conserving surgery: a meta-analysis. Int J Environ Res Public Health. 2019;16:4970.
Dominick SA, Natarajan L, Pierce JP, Madanat H, Madlensky L. The psychosocial impact of lymphedema-related distress among breast cancer survivors in the WHEL study. Psycho-Oncology. 2014;23:1049–56.
Laroche F, Perrot S, Medkour T, Cottu PH, Pierga JY, Lotz JP, et al. Quality of life and impact of pain in women treated with aromatase inhibitors for breast cancer. A multicenter cohort study. PLoS One. 2017;12:e0187165.
Saha P, Regan MM, Pagani O, Francis PA, Walley BA, Ribi K, et al. Treatment efficacy, adherence, and quality of life among women younger than 35 years in the international breast cancer study group TEXT and SOFT adjuvant endocrine therapy trials. J Clin Oncol. 2017;35:3113.
Richard A, Harbeck N, Wuerstlein R, Wilhelm FH. Recover your smile: effects of a beauty care intervention on depressive symptoms, quality of life, and self-esteem in patients with early breast cancer. Psychooncology. 2019;28(2):401–7.
Williams R, Müller M, Harewood R, Stanway S, Bhaskaran K, Carreira H. Associations between breast cancer survivorship and adverse mental health outcomes: a systematic review. J Natl Cancer Inst. 2018;110:1311.
Vadaparampil ST, Christie J, Donovan KA, Kim J, Augusto B, Kasting ML, et al. Health-related quality of life in Black breast cancer survivors with and without triple-negative breast cancer (TNBC). Breast Cancer Res Treat. 2017;163(2):331–42.
Hu Y, Liu T, Li F. Association between dyadic interventions and outcomes in cancer patients: a meta-analysis. Support Care Cancer. 2019;27:745–61.
Krug K, Miksch A, Peters-Klimm F, Engeser P, Szecsenyi J. Correlation between patient quality of life in palliative care and burden of their family caregivers: a prospective observational cohort study. BMC Palliat Care. 2016;15:4.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Marcou, Y. (2022). Quality of Life in Breast Cancer. In: Kassianos, A.P. (eds) Handbook of Quality of Life in Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-84702-9_22
Download citation
DOI: https://doi.org/10.1007/978-3-030-84702-9_22
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-84701-2
Online ISBN: 978-3-030-84702-9
eBook Packages: MedicineMedicine (R0)