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Osteoporosis in the Elderly

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Osteoporosis

Abstract

Osteoporosis in the elderly population presents unique diagnostic and therapeutic challenges. Assessment of fracture risk goes beyond measurement of bone density to include evaluation for sarcopenia, frailty, and falls. In addition, investigating comorbid conditions and risk factors provides significant insights into the musculoskeletal consequences of aging. Therefore, the management plan to reduce the risk of future fractures should include practical recommendations and achievable goals that fit with the individual patient’s preferences and overall health span.

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References

  1. Cruz-Jentoft AJ, et al. Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412–23.

    Article  Google Scholar 

  2. Studenski S, et al. Gait speed and survival in older adults. JAMA. 2011;305(1):50–8.

    Article  CAS  Google Scholar 

  3. Bischoff HA, et al. Identifying a cut-off point for normal mobility: a comparison of the timed “up and go” test in community-dwelling and institutionalised elderly women. Age Ageing. 2003;32(3):315–20.

    Article  Google Scholar 

  4. Alley DE, et al. Grip strength cutpoints for the identification of clinically relevant weakness. J Gerontol A Biol Sci Med Sci. 2014;69(5):559–66.

    Article  Google Scholar 

  5. Dodds RM, et al. Grip strength across the life course: normative data from twelve British studies. PLoS One. 2014;9(12):e113637.

    Article  Google Scholar 

  6. Kiely DK, et al. Identifying nursing home residents at risk for falling. J Am Geriatr Soc. 1998;46(5):551–5.

    Article  CAS  Google Scholar 

  7. Lawlor DA, Patel R, Ebrahim S. Association between falls in elderly women and chronic diseases and drug use: cross sectional study. BMJ. 2003;327(7417):712–7.

    Article  Google Scholar 

  8. Ensrud KE, et al. Central nervous system-active medications and risk for falls in older women. J Am Geriatr Soc. 2002;50(10):1629–37.

    Article  Google Scholar 

  9. Wu Q, et al. Selective serotonin reuptake inhibitor treatment and risk of fractures: a meta-analysis of cohort and case-control studies. Osteoporos Int. 2012;23(1):365–75.

    Article  CAS  Google Scholar 

  10. Rabenda V, et al. Relationship between use of antidepressants and risk of fractures: a meta-analysis. Osteoporos Int. 2013;24(1):121–37.

    Article  CAS  Google Scholar 

  11. Muir SW, Gopaul K, Montero Odasso MM. The role of cognitive impairment in fall risk among older adults: a systematic review and meta-analysis. Age Ageing. 2012;41(3):299–308.

    Article  Google Scholar 

  12. Brown JS, et al. Urinary incontinence: does it increase risk for falls and fractures? Study of Osteoporotic Fractures Research Group. J Am Geriatr Soc. 2000;48(7):721–5.

    Article  CAS  Google Scholar 

  13. Kanis JA, et al. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008;19(4):385–97.

    Article  CAS  Google Scholar 

  14. Berry SD, et al. Fracture risk assessment in long-term care (FRAiL): development and validation of a prediction model. J Gerontol A Biol Sci Med Sci. 2018;73(6):763–9.

    Article  Google Scholar 

  15. Visser M, Deeg DJ, Lips P. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab. 2003;88(12):5766–72.

    Article  CAS  Google Scholar 

  16. Cauley JA, et al. Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med. 2008;149(4):242–50.

    Article  Google Scholar 

  17. Zhao JG, et al. Association between calcium or vitamin D supplementation and fracture incidence in community-dwelling older adults: a systematic review and meta-analysis. JAMA. 2017;318(24):2466–82.

    Article  CAS  Google Scholar 

  18. Bischoff-Ferrari HA, et al. Effect of vitamin D on falls: a meta-analysis. JAMA. 2004;291(16):1999–2006.

    Article  CAS  Google Scholar 

  19. Uusi-Rasi K, et al. Exercise and vitamin D in fall prevention among older women: a randomized clinical trial. JAMA Intern Med. 2015;175(5):703–11.

    Article  Google Scholar 

  20. Reid IR. Osteoporosis: evidence for vitamin D and calcium in older people. Drug Ther Bull. 2020;58(8):122–5.

    Article  Google Scholar 

  21. Guirguis-Blake JM, et al. Interventions to prevent falls in older adults: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018;319(16):1705–16.

    Article  Google Scholar 

  22. Sherrington C, et al. Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2019;1(1):CD012424.

    PubMed  Google Scholar 

  23. Troy KL, et al. Exercise early and often: effects of physical activity and exercise on women’s bone health. Int J Environ Res Public Health. 2018;15(5):878.

    Article  Google Scholar 

  24. Dent E, et al. International Clinical Practice Guidelines for Sarcopenia (ICFSR): screening, diagnosis and management. J Nutr Health Aging. 2018;22(10):1148–61.

    Article  CAS  Google Scholar 

  25. WHO Guidelines Approved by the Guidelines Review Committee. Global recommendations on physical activity for health. Geneva: World Health Organization; 2010.

    Google Scholar 

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Correspondence to Jad G. Sfeir .

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Samakkarnthai, P., Sfeir, J.G. (2021). Osteoporosis in the Elderly. In: Cusano, N.E. (eds) Osteoporosis. Springer, Cham. https://doi.org/10.1007/978-3-030-83951-2_8

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  • DOI: https://doi.org/10.1007/978-3-030-83951-2_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-83950-5

  • Online ISBN: 978-3-030-83951-2

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