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Adversities of Nanoparticles in Elderly Populations

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Free Radical Biology and Environmental Toxicity

Part of the book series: Molecular and Integrative Toxicology ((MOLECUL))

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Abstract

In literature, several studies on nanotoxicity have been published which proved that nanoparticle entry inside the cell leads to many biochemical events, ultimately causing free radical generation, mitochondrial damage, cell injury, and cell death. Many in vivo and in vitro studies have proved that the use of nanoparticles in various fields requires prior safety and toxicology evaluation. In this study, the possible toxic effects of nanoparticles on different diseases are explored and various side effects of different types of nanoparticles have been reviewed. After doing a literature study, it has been found that nanoparticles affect elderly and susceptible population more as compared to young and adults.

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Acknowledgments

The authors thank the fraternity of University Institute of Biotechnology and also the University Center for Research and Development (UCRD) at Chandigarh University (CU) for support. All the authors have equally contributed to the manuscript and revised the manuscript. The institute to which the authors are currently affiliated, however, has no role in shaping the manuscript. All the authors declare no conflict of interest.

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Authors and Affiliations

  1. University Institute of Biotechnology, Chandigarh University, Mohali, Punjab, India

    Arti Devi & Gaurav Mudgal

  2. Faculty of Science, Baba Farid Group of Institutions,, Bathinda, Punjab, India

    Zaved Ahmed Khan

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  1. Arti Devi
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  2. Gaurav Mudgal
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Editors and Affiliations

  1. Department of Applied Physics and Department of Bioproducts and Biosystems School of Science, Aalto University, Espoo, Finland

    Kavindra Kumar Kesari

  2. Department of Biotechnology School of Engineering and Technology, Sharda University, Greater Noida, Uttar Pradesh, India

    Niraj Kumar Jha

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Devi, A., Mudgal, G., Khan, Z.A. (2021). Adversities of Nanoparticles in Elderly Populations. In: Kesari, K.K., Jha, N.K. (eds) Free Radical Biology and Environmental Toxicity. Molecular and Integrative Toxicology. Springer, Cham. https://doi.org/10.1007/978-3-030-83446-3_5

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