Skip to main content

Food Allergy and Intolerance: Diagnosis and Nutritional Management

  • Chapter
  • First Online:
Nutrition Guide for Physicians and Related Healthcare Professions

Part of the book series: Nutrition and Health ((NH))

  • 1622 Accesses

Abstract

Nontoxic food hypersensitivity is categorized as reactions that are either immune-mediated (food allergy; FA) or nonimmune-mediated (food intolerances). FA and food intolerances are growing public health concerns worldwide. Diagnosis of FA consists of clinical history combined with diagnostic testing (through skin prick testing or serum-specific immunoglobulin E [IgE] testing). Further investigation can be done using oral food challenge (OFC) and component-resolved diagnostics. Nutritional management of FA involves avoidance of exposure to the allergen and establishing through OFC whether baked forms of the allergen are tolerated. Oral immunotherapy can be considered for peanut allergy. Food intolerance is diagnosed with a clinical history, elimination diet, symptom improvement, and OFC, while breath tests can be performed to guide the elimination diet. Nutritional management of food intolerance does not usually require complete avoidance of the offending food(s), but determining tolerable amounts. Referral to a dietitian is necessary to help educate patients and plan nutritionally balanced and individualized elimination diets.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Turnbull JL, Adams HN, Gorard DA. Review article: the diagnosis and management of food allergy and food intolerances. Aliment Pharmacol Ther. 2015;41:3–25.

    Article  CAS  PubMed  Google Scholar 

  2. Anvari S, Miller J, Yeh CY, Davis CM. IgE-mediated food allergy. Clin Rev Allergy Immunol. 2019;57(2):244–60. https://doi.org/10.1007/s12016-018-8710-3.

    Article  CAS  PubMed  Google Scholar 

  3. Seth D, Poowutikul P, Pansare M, Kamat D. Food allergy: a review. Pediatr Ann. 2020;49(1):e50–8. https://doi.org/10.3928/19382359-20191206-01.

    Article  PubMed  Google Scholar 

  4. Ho MH, Wong WH, Chang C. Clinical spectrum of food allergies: a comprehensive review. Clin Rev Allergy Immunol. 2014;46:225–40.

    Article  CAS  PubMed  Google Scholar 

  5. Oriel RC, Wang J. Diagnosis and Management of Food Allergy. Pediatr Clin N Am. 2019;66(5):941–54. https://doi.org/10.1016/j.pcl.2019.06.002.

    Article  Google Scholar 

  6. Food Allergy Research and Education (FARE). Food allergy facts and statistics for the US. https://www.foodallergy.org/resources/food-allergy-facts-and-statistics-us.

  7. Tuck CJ, Biesiekierski JR, Schmid-Grendelmeier P, Pohl D. Food intolerances. Nutrients. 2019;11(7):1684. https://doi.org/10.3390/nu11071684.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Abrams EM, Chan ES. Prevention of non-peanut food allergies. Curr Allergy Asthma Rep. 2019;19(12):60. https://doi.org/10.1007/s11882-019-0891-1.

    Article  PubMed  Google Scholar 

  9. Barni S, Liccioli G, Sarti L, Giovannini M, Novembre E, Mori F. Immunoglobulin E (IgE)-mediated food allergy in children: epidemiology, pathogenesis, diagnosis, prevention, and management. Medicina (Kaunas). 2020;56(3):111. https://doi.org/10.3390/medicina56030111.

    Article  PubMed  Google Scholar 

  10. Bartuzi Z, Kaczmarski M, Czerwionka-Szaflarska M, Małaczyńska T, Krogulska A. The diagnosis and management of food allergies. Position paper of the food allergy section the polish Society of Allergology. Postepy Dermatol Alergol. 2017;34(5):391–404. https://doi.org/10.5114/ada.2017.71104.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Iweala OI, Choudhary SK, Commins SP. Food allergy. Curr Gastroenterol Rep. 2018;20(5):17. https://doi.org/10.1007/s11894-018-0624-y.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Labrosse R, Graham F, Caubet JC. Non-IgE-mediated gastrointestinal food allergies in children: an update. Nutrients. 2020;12(7):2086. https://doi.org/10.3390/nu12072086.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Muraro A, Werfel T, Hoffmann-Sommergruber K, et al. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy. Allergy. 2014;69:1008–25.

    Article  CAS  PubMed  Google Scholar 

  14. Wright BL, Walkner M, Vickery BP, Gupta RS. Clinical management of food allergy. Pediatr Clin N Am. 2015;62:1409–24.

    Article  Google Scholar 

  15. Venter C, Groetch M, Netting M, Meyer R. A patient-specific approach to develop an exclusion diet to manage food allergy in infants and children. Clin Exp Allergy. 2018;48(2):121–37. https://doi.org/10.1111/cea.13087.

    Article  CAS  PubMed  Google Scholar 

  16. Robinson ML, Lanser BJ. The role of baked egg and Milk in the diets of allergic children. Immunol Allergy Clin N Am. 2018;38(1):65–76. https://doi.org/10.1016/j.iac.2017.09.007.

    Article  Google Scholar 

  17. Togias A, Cooper SF, Acebal ML, et al. Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017;139:29–44.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Kim EH, Burks AW. Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy. Allergy. 2020;75(6):1337–46. https://doi.org/10.1111/all.14220.

    Article  PubMed  Google Scholar 

  19. Mehtab W, Agarwal A, Singh N, Malhotra A, Makharia GK. All that a physician should know about FODMAPs. Indian J Gastroenterol. 2019;38(5):378–90. https://doi.org/10.1007/s12664-019-01002-0.

    Article  PubMed  Google Scholar 

  20. Andreozzi L, Giannetti A, Cipriani F, Caffarelli C, Mastrorilli C, Ricci G. Hypersensitivity reactions to food and drug additives: problem or myth? Acta Biomed. 2019;90(3-S):80–90. https://doi.org/10.23750/abm.v90i3-S.8168.

    Article  CAS  PubMed  Google Scholar 

  21. Facioni MS, Raspini B, Pivari F, Dogliotti E, Cena H. Nutritional management of lactose intolerance: the importance of diet and food labelling. J Transl Med. 2020;18(1):260. https://doi.org/10.1186/s12967-020-02429-2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Suggested Further Readings

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Janetta Harbron .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Harbron, J. (2022). Food Allergy and Intolerance: Diagnosis and Nutritional Management. In: Wilson, T., Temple, N.J., Bray, G.A. (eds) Nutrition Guide for Physicians and Related Healthcare Professions. Nutrition and Health. Humana, Cham. https://doi.org/10.1007/978-3-030-82515-7_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-82515-7_20

  • Published:

  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-82514-0

  • Online ISBN: 978-3-030-82515-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics