Abstract
Total pancreatectomy is an operation which can be used for both benign and malignant diseases of the pancreas. Because of the resulting complete exocrine and endocrine insufficiency, this surgery is reserved for patients who have failed medical management or are not candidates for less extensive surgery. Although historically associated with high risk, recent reports have demonstrated that modern post-operative treatment regimens can result in morbidity and mortality rates comparable with those of partial pancreatectomy patients. This chapter concentrates on the additional features necessary to complete the pancreatic resection and should be read in conjunction with Chap. 96.
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Further Reading
Almond M, Roberts KJ, Hodson J, et al. Changing indications for total pancreatectomy: perspectives over a quarter of a century. HPB (Oxford). 2015;17(5):416–21.
Dresler CM, Fortner JG, McDermott K, et al. Metabolic consequences of (regional) total pancreatectomy. Ann Surg. 1991;214(2):131–40.
Hartwig W, Gluth A, Hinz U, et al. Total pancreatectomy for primary pancreatic neoplasms: renaissance of an unpopular operation. Ann Surg. 2015;261(3):537–46.
Heidt DG, Burant C, Simeone DM. Total pancreatectomy: indications, operative technique, and postoperative sequelae. J Gastrointest Surg. 2007;11(2):209–16.
Kulu Y, Schmied BM, Werner J, et al. Total pancreatectomy for pancreatic cancer: indications and operative technique. HPB (Oxford). 2009;11(6):469–75.
Müller MW, Friess H, Kleeff J, et al. Is there still a role for total pancreatectomy? Ann Surg. 2007;246(6):966–74; discussion 974–5
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Feferman, Y., Sarpel, U. (2022). Total Pancreatoduodenectomy. In: Scott-Conner, C.E.H., Kaiser, A.M., Nguyen, N.T., Sarpel, U., Sugg, S.L. (eds) Chassin's Operative Strategy in General Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-81415-1_97
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DOI: https://doi.org/10.1007/978-3-030-81415-1_97
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