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Ellagitannins

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Handbook of Food Bioactive Ingredients

Abstract

Ellagitannins (ET) are phytochemicals with potent antioxidant properties found in many natural foods. In particular, ETs have been studied extensively in pomegranate juice, extracts, and supplements. In this book chapter we provide details on the sources of ETs, ET digestion and metabolism into ellagic acid (EA) which are further metabolized into different urolithins via the gut microbiota. The chapter then expands on the bioavailability of ETs, EA, and urolithins followed by a review of their main health benefits, particularly in relation to cardiovascular disease, type 2 diabetes, and cancer with a focus on antioxidant activity. We review the toxicology data from human and in vivo studies which highlight the safety of ET foods and supplements even at high doses. Finally, we report on ET’s current and future applications in the nutraceutical and functional food ingredients industries, including potential carrier systems and quality control for product development.

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Ahmed Nasef, N., Rosendale, D., McKeen, S. (2022). Ellagitannins. In: Jafari, S.M., Rashidinejad, A., Simal-Gandara, J. (eds) Handbook of Food Bioactive Ingredients. Springer, Cham. https://doi.org/10.1007/978-3-030-81404-5_11-1

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