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Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision

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GeNeDis 2020

Abstract

Precision medicine, also known as personalized medicine, is concerned with finding the right treatment for the right patient at the right time. It is a way of thinking focused on parsing heterogeneity ultimately down to the level of the individual. Its main mission is to identify characteristics of heterogeneous clinical conditions so as to target tailored therapies to individuals. Precision Medicine however is not an agnostic collection of all manner of clinical, genetic and other biologic data in select cohorts. This is an important point. Simply collecting as much information as possible on individuals without applying this way of thinking should not be considered Precision Medicine.

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Acknowledgments

We are grateful to the many supporters of the Richman Center and to Jiaxin Li for the development of Fig. 5. Dr. Kapogiannis’ effort is supported in part by the Intramural Research Program, National Institute on Aging (NIA/NIH).

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Correspondence to Constantine G. Lyketsos .

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Avramopoulos, D. et al. (2021). Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision. In: Vlamos, P. (eds) GeNeDis 2020. Advances in Experimental Medicine and Biology, vol 1339. Springer, Cham. https://doi.org/10.1007/978-3-030-78787-5_49

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