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Evaluation of Clinical Significance in Intervention Research

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Contemporary Obstetrics and Gynecology for Developing Countries

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Abstract

Intervention research has been an essential part of medicine since the eighteenth century. Still, its application for the betterment of human conditions is contemporary, and much remained unknown. The importance of intervention research cannot be overemphasised because it forms the centrepiece of one of the three fundamental pillars of evidence-based practice. Most high- impact scientific journals now require authors of intervention studies to assess the clinical relevance of any observed statistically significant difference associated with treatment. This chapter explores the fundamentals of the clinical significance concept and provides a step-by-step illustration of how to compute and interpret Cohen-d and η2 estimates. It also examines web-based resources for calculating clinical significance estimates for different experimental research designs. Additionally, the chapter offer insights on how to assess the underlying assumptions associated with the parametric tests. Applying the concepts presented in this chapter will open the floodgate for improved evidence-based intervention studies in medicine and allied health. The more researchers take part in intervention research, the faster we can answer essential clinical questions that will help us prevent emerging diseases and find more effective treatments.

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Author information

Authors and Affiliations

  1. Chicago State University, Chicago, IL, USA

    Joseph A. Balogun

  2. University of Medical Sciences, Ondo City, Nigeria

    Joseph A. Balogun

  3. Centre of Excellence in Reproductive Health Innovation, University of Benin, Benin City, Nigeria

    Joseph A. Balogun

Authors
  1. Joseph A. Balogun
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Correspondence to Joseph A. Balogun .

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Editors and Affiliations

  1. Centre of Excellence in Reproductive Health Innovation, Department of Obstetrics and Gynaecology, University of Benin, Benin City, Nigeria

    Friday Okonofua

  2. College of Health Sciences, Chicago State University, Chicago, IL, USA

    Joseph A. Balogun

  3. Roswell Park Cancer Institute, Buffalo, NY, USA

    Kunle Odunsi

  4. Clinical Obstetrics and Gynaecology, Weil Cornell Medicine, Doha, Qatar

    Victor N. Chilaka

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Balogun, J.A. (2021). Evaluation of Clinical Significance in Intervention Research. In: Okonofua, F., Balogun, J.A., Odunsi, K., Chilaka, V.N. (eds) Contemporary Obstetrics and Gynecology for Developing Countries . Springer, Cham. https://doi.org/10.1007/978-3-030-75385-6_67

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  • DOI: https://doi.org/10.1007/978-3-030-75385-6_67

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-75384-9

  • Online ISBN: 978-3-030-75385-6

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